质量水平
技术
cell based assay: suitable
cell culture | mammalian: suitable
mp
>210 °C (dec.) (lit.)
适用性
suitable for molecular biology
SMILES字符串
CS(=N)(=O)CC[C@H](N)C(O)=O
InChI
1S/C5H12N2O3S/c1-11(7,10)3-2-4(6)5(8)9/h4,7H,2-3,6H2,1H3,(H,8,9)/t4-,11?/m0/s1
InChI key
SXTAYKAGBXMACB-DPVSGNNYSA-N
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应用
使用高水平的 MSX 可以提高多种重组 GS CHO 细胞系和 GS–CHOK1SV 细胞系的生产率和生产稳定性，而不会影响产品质量。这些发现对于提高生物制品生产中使用的工业细胞培养过程的效率和可靠性具有重要意义。
MSX 是一种强效惊厥剂，已显示出对原代皮质星形胶质细胞培养物中谷氨酰胺动态具有特定且显著的影响。这使其成为研究和调节细胞培养中谷氨酰胺相关过程的有价值的化合物。
生化/生理作用
警示用语：
Warning
危险分类
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
分析证书(COA)
输入产品批号来搜索 分析证书(COA) 。批号可以在产品标签上"批“ （Lot或Batch）字后找到。
难以找到您所需的产品或批次号码？
如何查找产品货号
在网站页面上，产品编号会附带包装尺寸/数量一起显示（例如：T1503-25G）。请确保 在“产品编号”字段中仅输入产品编号 (示例: T1503).
示例
其它示例：
705578-5MG-PW
PL860-CGA/SHF-1EA
MMYOMAG-74K-13
1000309185
输入内容 1.000309185)
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如何查找COA批号
批号可以在产品标签上"批“ （Lot或Batch）字后面找到。
Aldrich 产品
如果您查询到的批号为 TO09019TO 等，请输入去除前两位字母的批号：09019TO。
如果您查询到的批号含有填充代码（例如05427ES-021），请输入去除填充代码-021的批号：05427ES。
如果您查询到的批号含有填充代码（例如 STBB0728K9），请输入去除填充代码K9的批号：STBB0728。
未找到您寻找的产品？
部分情况下，可能未在线提供COA。如果搜索不到COA，可在线索取。
Which document(s) contains shelf-life or expiration date information for a given product?
If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.
How do I get lot-specific information or a Certificate of Analysis?
The lot specific COA document can be found by entering the lot number above under the "Documents" section.
How do I find price and availability?
There are several ways to find pricing and availability for our products. Once you log onto our website, you will find the price and availability displayed on the product detail page. You can contact any of our Customer Sales and Service offices to receive a quote. USA customers: 1-800-325-3010 or view local office numbers.
What is the Department of Transportation shipping information for this product?
Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.
What is the solubility of Product M5379, L-Methionine sulfoximine?
We test the solubility at 50 mg/mL (0.277 M) in water; heat and/or sonication may be required.
What is the solution stability of Product M5379, L-Methionine sulfoximine?
We do not have any information available on solution stability. The following references may provide some helpful information:1. Proc. Roy. Soc., 138, 265 (1951).2. Weisbrod, R. E., and Meister, A., Studies on Glutamine Synthetase from Escherichia Coli. Formation of Pyrrolidone Carboxylate and Inhibition by Methionine Sulfoximine. J.Biol. Chem., 248(11), 3997-4002 (1973).3. Richman, P. G., et al., Inhibition of Gamma-glutamylcysteine Synthetase by L-methionine-S-sulfoximine. J. Biol. Chem., 248(19), 6684-6690 (1973).
How is Product M5379, L-Methionine sulfoximine, used?
This product has been reported as an inhibitor of glutamine synthetase by Weisbrod, R. E., et al., J.Biol. Chem., 248(11), 3997-4002 (1973). It has also been reported as an inhibitor of γ-glutamylcysteine synthetase by Richman, P. G., et al., J. Biol. Chem., 248(19), 6684-6690 (1973).
My question is not addressed here, how can I contact Technical Service for assistance?
Ask a Scientist here.
实验方案
LC/MS Analysis of L-Methionine Sulfoximine and Sulfone on Ascentis® Express OH5
Separation of L-Methionine sulfone; L-Methionine sulfoximine; L-Methionine sulfoxide
Chromatograms
application for HPLCapplication for HPLC我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
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