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Merck
CN

N3002

双(对硝基苯基)磷酸盐 钠盐

chromogenic, ≥99% (TLC), powder

别名:

BNPP sodium salt, Sodium bis(4-nitrophenyl) phosphate

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关于此项目

线性分子式:
C12H8O8N2PNa
化学文摘社编号:
分子量:
362.16
NACRES:
NA.32
PubChem Substance ID:
UNSPSC Code:
12352204
EC Number:
223-739-2
MDL number:
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产品名称

双(对硝基苯基)磷酸盐 钠盐, ≥99% (TLC)

InChI key

NXXNKMXTNUUECE-UHFFFAOYSA-N

InChI

1S/C12H9N2O8P.Na.H/c15-13(16)9-1-5-11(6-2-9)21-23(19,20)22-12-7-3-10(4-8-12)14(17)18;;/h1-8H,(H,19,20);;

SMILES string

[Na].OP(=O)(Oc1ccc(cc1)N(=O)=O)Oc2ccc(cc2)N(=O)=O

assay

≥99% (TLC)

form

powder

impurities

≤0.05% free p-nitrophenol

solubility

water: 20 mg/mL, clear to very slightly hazy

storage temp.

−20°C

Quality Level

General description

磷酸二酯酶底物

Application

双( p -硝基苯基)磷酸钠盐已被用作磷酸二酯酶 (PDE) 活性估计的底物。 在 PDE 抑制试验中也用作底物。

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


历史批次信息供参考:

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Soper AS and Aird SD
Journal of Chromatography A, 1154(1-2), 308-318 (2007)
6-Nitrobenzimidazole derivatives: Potential phosphodiesterase inhibitors: Synthesis and structure-activity relationship
Khan KM, et al.
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Nucleotidase and DNase activities in Brazilian snake venoms
Sales PB, et al.
Comparative Biochemistry and Physiology. Toxicology & Pharmacology : CBP, 147(1), 85-95 (2008)
Nele Steens et al.
Dalton transactions (Cambridge, England : 2003), (2)(2), 585-592 (2009-12-22)
Hydrolysis of 4-nitrophenyl phosphate (NPP) and bis-4-nitrophenyl phosphate (BNPP), two commonly used DNA model substrates, was examined in vanadate solutions by means of (1)H, (31)P and (51)V NMR spectroscopy. The hydrolysis of the phosphoester bond in NPP at 50 degrees
M-C Chang et al.
Acta biomaterialia, 8(3), 1380-1387 (2011-09-29)
Biocompatibility of dentin bonding agents (DBA) and composite resin may affect the treatment outcome (e.g., healthy pulp, pulpal inflammation, pulp necrosis) after operative restoration. Bisphenol-glycidyl methacrylate (BisGMA) is one of the major monomers present in DBA and resin. Prior studies

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