N8000
丁酸 1-萘酯
esterase substrate, ≥99% (GC), liquid
别名:
丁酸-1-萘基酯, 丁酸-1-萘酯
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线性分子式:
CH3CH2CH2CO2C10H7
化学文摘社编号:
分子量:
214.26
NACRES:
NA.32
PubChem Substance ID:
UNSPSC Code:
12352204
EC Number:
221-500-7
MDL number:
Beilstein/REAXYS Number:
2558646
产品名称
丁酸 1-萘酯, esterase substrate
InChI
1S/C14H14O2/c1-2-6-14(15)16-13-10-5-8-11-7-3-4-9-12(11)13/h3-5,7-10H,2,6H2,1H3
InChI key
XIVJNRXPRQKFRZ-UHFFFAOYSA-N
SMILES string
CCCC(=O)Oc1cccc2ccccc12
description
esterase substrate
assay
≥99% (GC)
form
liquid
refractive index
n20/D 1.571 (lit.)
bp
125-130 °C/1 mmHg (lit.)
solubility
ethanol: 100 mg/mL, clear, colorless to faintly yellow
density
1.091 g/mL at 20 °C (lit.)
storage temp.
−20°C
Quality Level
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Application
1-丁酸萘酯已被作为酯酶活性的底物，用于绵羊体虱 Bovicola ovis以及龙利鱼样本显色染色中。
Biochem/physiol Actions
1-丁酸萘酯又称为α-丁酸萘酯，是酯酶的底物。α-丁酸萘酯有助于评估单核细胞和淋巴细胞中的α-丁酸萘酯酶活性。
General description
酯酶底物。
存储类别
10 - Combustible liquids
wgk
WGK 3
flash_point_f
143.6 °F - closed cup
flash_point_c
62 °C - closed cup
ppe
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
M S Levine et al.
Journal of occupational medicine. : official publication of the Industrial Medical Association, 28(3), 207-211 (1986-03-01)
A cross-sectional review of routine employee health status examinations has identified an undercounting of circulating monocytes associated with an inhibition of a surface monocyte esterase, alpha-naphthyl butyrate esterase. It is postulated that this inhibition is associated with an organophosphate used
T Honda et al.
Histochemistry, 77(3), 299-302 (1983-01-01)
The proteases of human leukocytes were cytochemically studied by use of new alpha-naphthyl esters, tosyl-L-lysine-alpha-naphthyl ester (TLNE) and acetyl-L-tyrosine-alpha-naphthyl ester (ATNE). The hydrolytic activities were strong only in neutrophils, with both substrates. They were inhibited completely by DFP and chymostatin
Identification of alpha-naphthyl butyrate esterase as a plasma membrane ectoenzyme of monocytes and as a discrete intracellular membrane-bounded organelle in lymphocytes.
Bozdech MJ and Bainton DF
The Journal of Experimental Medicine, 153(1), 182-195 (1981)
R B Miller et al.
Journal of biochemical and biophysical methods, 3(6), 345-354 (1980-12-01)
We have developed a spectrophotometric assay method which continuously records esterase activity at 510 nm by monitoring absorbance changes due to the formation of a diazo dye complex. In our method, alpha-naphthyl ester substrates are hydrolyzed by enzymatic action to
Esterases of the flounder (Platichthys flesus, Pleuronectidae, Teleostei): development of an identification protocol using starch gel electrophoresis and characterization of loci
Berrebi P, et al.
Experientia, 46(8), 863-867 (1990)
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