Merck
CN

O5250

Sigma-Aldrich

D-鸟氨酸 单盐酸盐

~98%

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别名:
(R)-2,5-二氨基戊酸 单盐酸盐
经验公式(希尔记法):
C5H12N2O2 · HCl
CAS号:
分子量:
168.62
Beilstein:
4153339
EC 号:
MDL编号:
PubChem化学物质编号:

检测方案

~98%

形式

powder

颜色

white

mp

239 °C

SMILES string

Cl[H].NCCC[C@@H](N)C(O)=O

InChI

1S/C5H12N2O2.ClH/c6-3-1-2-4(7)5(8)9;/h4H,1-3,6-7H2,(H,8,9);1H/t4-;/m1./s1

InChI key

GGTYBZJRPHEQDG-PGMHMLKASA-N

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相关类别

生化/生理作用

D-鸟氨酸在半胱氨酸残基处裂解蛋白质。

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)


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Susan E Cellitti et al.
Nature chemical biology, 7(8), 528-530 (2011-04-29)
D-ornithine has previously been suggested to enhance the expression of pyrrolysine-containing proteins. We unexpectedly discovered that uptake of D-ornithine results in the insertion of a new amino acid, pyrroline-carboxy-lysine (Pcl) instead of the anticipated pyrrolysine (Pyl). Our feeding and biochemical
Nicole Berthold et al.
Antimicrobial agents and chemotherapy, 57(1), 402-409 (2012-11-02)
Proline-rich antimicrobial peptides (PrAMPs) from insects and mammals have recently been evaluated for their pharmaceutical potential in treating systemic bacterial infections. Besides the native peptides, several shortened, modified, or even artificial sequences were highly effective in different murine infection models.
Isabel Araque et al.
Food microbiology, 33(1), 107-113 (2012-11-06)
The accumulation of citrulline and ornithine in wine or beer as a result of the arginine catabolism of some lactic acid bacteria (LAB) species increases the risk of ethyl carbamate and putrescine formation, respectively. Several LAB species, which are found
Sherry Dadsetan et al.
Biochemical pharmacology, 85(1), 115-123 (2012-10-30)
Combined administration of ornithine and phenylacetate (OP) is proposed as a novel treatment of hyperammonemia and hepatic encephalopathy. Ornithine is believed to increase ammonia fixation into glutamine in muscle tissue and glutamine is subsequently thought to react with phenylacetate forming
Manami Oya et al.
The Journal of biological chemistry, 288(7), 4513-4521 (2012-12-28)
Although amino acids are dietary nutrients that evoke the secretion of glucagon-like peptide 1 (GLP-1) from intestinal L cells, the precise molecular mechanism(s) by which amino acids regulate GLP-1 secretion from intestinal L cells remains unknown. Here, we show that

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