O6754
1-油酰基-2-乙酰基-sn-丙三醇
≥97% (TLC), oil
别名:
1-(顺-9-油酰基)-2-乙酰基-sn-甘油, 2-乙酰基-1-油酰基-sn-甘油, DG (18:1 (9 Z )/2:0/0:0), OAG
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关于此项目
经验公式（希尔记法）:
C23H42O5
CAS Number:
分子量:
398.58
Beilstein:
8168731
MDL编号:
UNSPSC代码:
12352211
PubChem化学物质编号:
NACRES:
NA.25
生物来源
synthetic (organic)
质量水平
方案
≥97% (TLC)
表单
oil
溶解性
ethanol: 20 mg/mL (lit.)(lit.)
DMSO: soluble (lit.)(lit.)
官能团
ketone
脂质类型
neutral glycerides
运输
dry ice
储存温度
−20°C
SMILES字符串
CCCCCCCC\C=C/CCCCCCCC(=O)OC[C@H](CO)OC(C)=O
InChI
1S/C23H42O5/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-23(26)27-20-22(19-24)28-21(2)25/h10-11,22,24H,3-9,12-20H2,1-2H3/b11-10-/t22-/m0/s1
InChI key
PWTCCMJTPHCGMS-YRBAHSOBSA-N
基因信息
human ... PRKCA(5578)
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生化/生理作用
1-油酰-2-乙酰基- 锡 -甘油是一种合成的、细胞渗透性的甘油二酯类似物。常作为钙依赖性蛋白激酶 C (PKC) 的激活剂。
免责声明
储存中或成溶液时可能发生异构化。
储存分类代码
10 - Combustible liquids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
Christian Feisst et al.
Cellular and molecular life sciences : CMLS, 66(16), 2759-2771 (2009-07-07)
We previously showed that, in vitro, hyperforin from St. John's wort (Hypericum perforatum) inhibits 5-lipoxygenase (5-LO), the key enzyme in leukotriene biosynthesis. Here, we demonstrate that hyperforin possesses a novel and unique molecular pharmacological profile as a 5-LO inhibitor with
Nao Nishida-Aoki et al.
Metabolites, 10(2) (2020-02-20)
Extracellular vesicles (EVs) are lipid bilayer nanovesicles secreted from almost all cells including cancer. Cancer-derived EVs contribute to cancer progression and malignancy via educating the surrounding normal cells. In breast cancer, epidemiological and experimental observations indicated that lipids are associated
Meng Zhu et al.
Nature communications, 8(1), 921-921 (2017-10-17)
Establishment of cell polarity in the mammalian embryo is fundamental for the first cell fate decision that sets aside progenitor cells for both the new organism and the placenta. Yet the sequence of events and molecular mechanism that trigger this
Saifur Rahman et al.
Scientific reports, 7(1), 12881-12881 (2017-10-19)
The store-operated calcium entry (SOCE) pathway is an important route for generating cytosolic Ca
Tom Litjens et al.
The Biochemical journal, 405(2), 269-276 (2007-04-17)
Repetitive hormone-induced changes in concentration of free cytoplasmic Ca2+ in hepatocytes require Ca2+ entry through receptor-activated Ca2+ channels and SOCs (store-operated Ca2+ channels). SOCs are activated by a decrease in Ca2+ concentration in the intracellular Ca2+ stores, but the molecular
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