P6155
吡哆醛 盐酸盐
BioReagent, suitable for cell culture, suitable for insect cell culture
别名:
3-羟基-5-(羟甲基)-2-甲基-4-吡啶甲醛 盐酸盐, PL HCl
产品线
BioReagent
质量水平
方案
≥99% (HPLC)
表单
powder
分子量
Mw 203.62 g/mol
技术
cell culture | insect: suitable
cell culture | mammalian: suitable
颜色
white to off-white
mp
173 °C (dec.) (lit.)
溶解性
water: soluble 50 mg/mL, clear, colorless to light greenish-yellow
储存温度
−20°C
SMILES字符串
Cl[H].[H]C(=O)c1c(CO)cnc(C)c1O
InChI
1S/C8H9NO3.ClH/c1-5-8(12)7(4-11)6(3-10)2-9-5;/h2,4,10,12H,3H2,1H3;1H
InChI key
FCHXJFJNDJXENQ-UHFFFAOYSA-N
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一般描述
吡哆醛是一种杂环化合物,分子量为167.2 Da。它是维生素B6的天然形式之一。已发现吡哆醛的稳定性低于吡哆醇,因此,加热可能会导致其作用丧失。吡哆醛来源广泛,存在于动植物中。吡哆醛可作为有效的辅酶前体:磷酸吡哆醛和磷酸吡哆胺。
应用
吡哆醛盐酸盐已被用于研究其对鼠类黑色素瘤细胞的增殖和黑色素生成的影响。
用于标记氨基酸及其皮摩尔量的检测;辅酶和辅因子,第一卷:维生素 B6,磷酸吡哆醛
储存分类代码
11 - Combustible Solids
WGK
WGK 2
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
David C Nieman and Robert D lee
Nutritional Assessment (2016)
Berdanier CD and Berdanier LA et al.
Advanced nutrition: macronutrients, micronutrients, and metabolism (2015)
The effects of vitamin B6 compounds on cell proliferation and melanogenesis in B16F10 melanoma cells
Matsuo T, et al.
Oncology Letters, 15(4), 5181-5184 (2018)
Gerta Hoxhaj et al.
Science (New York, N.Y.), 363(6431), 1088-1092 (2019-03-09)
Nicotinamide adenine dinucleotide phosphate (NADP+) is essential for producing NADPH, the primary cofactor for reductive metabolism. We find that growth factor signaling through the phosphoinositide 3-kinase (PI3K)-Akt pathway induces acute synthesis of NADP+ and NADPH. Akt phosphorylates NAD kinase (NADK)
Lucia Carrano et al.
BioMed research international, 2015, 419383-419383 (2015-09-09)
With the increasing need of effective antibiotics against multi-drug resistant pathogens, lantibiotics are an attractive option of a new class of molecules. They are ribosomally synthetized and posttranslationally modified peptides possessing potent antimicrobial activity against aerobic and anaerobic Gram-positive pathogens
商品
该页面针对维生素B6、吡哆醛和吡哆醇如何影响无血清、无蛋白细胞培养系统(用于包括单克隆抗体在内的异源蛋白的生物制造)的性能提供了全面的分析。本页介绍吡哆醛、吡哆醇的体外化学和生物化学。
Vitamin B6's impact on serum-free cell culture systems is explored for protein manufacturing.
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