P7903
吡哌酸
别名:
8-乙基-5,8-二氢-5-氧-2-(1-哌嗪基)吡啶并(2,3-d)嘧啶-6-羧酸
登录查看公司和协议定价
关于此项目
经验公式（希尔记法）:
C14H17N5O3
CAS Number:
分子量:
303.32
EC 号:
MDL编号:
UNSPSC代码:
51282938
PubChem化学物质编号:
NACRES:
NA.85
表单
powder
抗生素抗菌谱
Gram-negative bacteria
Gram-positive bacteria
作用机制
DNA synthesis | interferes
cell wall synthesis | interferes
enzyme | inhibits
SMILES字符串
CCN1C=C(C(O)=O)C(=O)c2cnc(nc12)N3CCNCC3
InChI
1S/C14H17N5O3/c1-2-18-8-10(13(21)22)11(20)9-7-16-14(17-12(9)18)19-5-3-15-4-6-19/h7-8,15H,2-6H2,1H3,(H,21,22)
InChI key
JOHZPMXAZQZXHR-UHFFFAOYSA-N
基因信息
human ... CYP1A2(1544)
一般描述
化学结构：喹诺酮
应用
吡哌酸被用于研究DNA损伤和诱变活性。它已被用于诱导新生小鼠的关节病变，并用于研究人淋巴细胞胚细胞生成和干扰素的产生。
生化/生理作用
吡哌酸可调节（抑制）细菌DNA促旋酶依赖性过程，如DNA聚合、（ATP依赖性）DNA超螺旋和染色体断裂。已有研究显示，吡哌酸可诱导淋巴细胞DNA合成的抑制。
分析说明
在水中极微溶解。它溶于酸和碱金属氢氧化物的稀释溶液。
其他说明
10g,100g
保持容器密封，存放在干燥，通风良好的地方。保持干燥
警示用语：
Danger
危险声明
危险分类
Resp. Sens. 1 - Skin Sens. 1
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
Xiao X Han et al.
Analytical chemistry, 81(9), 3350-3355 (2009-04-14)
For surface-enhanced Raman scattering (SERS)-based protein identification, immunoassay, and drug screening, metal sandwich substrates bridged by proteins have been created in the present study. The sandwich architectures are fabricated based on a layer-by-layer (LbL) technique. The first gold monolayer is
Quinolone-Induced Arthropathy in the Neonatal Mouse: Morphological Analysis of Articular Lesions Produced by Pipemidic Acid and Ciprofloxacin1
DANIEL A. LINSEMAN, LAURIE A. HAMPTON, et al.
Toxicological Sciences, 28, 59-64 (1995)
I Grabnar et al.
International journal of pharmaceutics, 322(1-2), 52-59 (2006-06-30)
Intravesical administration of cytotoxic agents is commonly used in urological practice for treatment of superficial bladder cancer. The leading motive is optimisation of drug delivery near the site of action and reduction of systemic toxicity. Bladder pharmacokinetics is complicated by
Adrián Jaén-Gil et al.
Journal of chromatography. A, 1568, 57-68 (2018-06-19)
The evaluation of wastewater treatment capabilities in terms of removal of water pollutants is crucial when assessing water mitigation issues. Not only the monitoring of target pollutants becomes a critical point, but also the transformation products (TPs) generated. Since these
Margherita Lavorgna et al.
International journal of molecular sciences, 20(2) (2019-01-24)
Pipemidic acid (HPPA) is a quinolone antibacterial agent used mostly to treat gram-negative infections of the urinary tract, but its therapeutic use is limited because of its low solubility. Thus, to improve drug solubility, natural cyclodextrins (CDs) are used for
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持