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Merck
CN

S1013

(−)-东莨菪碱 盐酸盐

≥90% (HPLC), powder

别名:

天仙子碱 盐酸盐, 莨菪胺

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关于此项目

经验公式(希尔记法):
C17H21NO4 · HCl
化学文摘社编号:
分子量:
339.81
EC Number:
200-225-6
UNSPSC Code:
12352200
PubChem Substance ID:
Beilstein/REAXYS Number:
4168778
MDL number:
Assay:
≥90% (HPLC)
Form:
powder
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assay

≥90% (HPLC)

form

powder

optical activity

[α]25/D ~−27°, c = 1 in H2O(lit.)

color

white

solubility

H2O: 50 mg/mL

SMILES string

Cl.[H][C@]12C[C@H](C[C@]([H])(N1C)[C@]3([H])O[C@]23[H])OC(=O)[C@H](CO)c4ccccc4

InChI

1S/C17H21NO4.ClH/c1-18-13-7-11(8-14(18)16-15(13)22-16)21-17(20)12(9-19)10-5-3-2-4-6-10;/h2-6,11-16,19H,7-9H2,1H3;1H/t11-,12-,13-,14+,15-,16+;/m1./s1

InChI key

KXPXJGYSEPEXMF-MOUKNHLCSA-N

Gene Information

human ... CHRM1(1128)

Biochem/physiol Actions

竞争性非选择性毒蕈碱型乙酰胆碱拮抗剂。
竞争性非选择性毒蕈碱型乙酰胆碱拮抗剂。东莨菪碱所致的实验室动物记忆障碍是常用的记忆缺陷模型。

Disclaimer

The powder is stable at least four years stored at room temperature.


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pictograms

Skull and crossbonesCorrosion

signalword

Danger

Hazard Classifications

Acute Tox. 1 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - Eye Dam. 1 - Skin Sens. 1

存储类别

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk

WGK 3

flash_point_f

170.6 °F - closed cup

flash_point_c

77 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

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Stacey J Sukoff Rizzo et al.
Current protocols in mouse biology, 8(2), e45-e45 (2018-06-21)
The relationship between chronological age (lifespan) and biological age (healthspan) varies amongst individuals. Understanding the normal trajectory and characteristic traits of aging mice throughout their lifespan is important for selecting the most reliable and reproducible measures to test hypotheses. The
X Bian et al.
Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society, 21(9), 969-977 (2009-04-21)
Neuromuscular transmission is crucial for normal gut motility but little is known about its postnatal maturation. This study investigated excitatory/inhibitory neuromuscular transmission in vitro using ileal nerve-muscle preparations made from neonatal (< or =48 h postnatal) and adult ( approximately
Sunjoo Joo et al.
Nature communications, 13(1), 1133-1133 (2022-03-05)
Most sexual organisms inherit organelles from one parent, commonly by excluding organelles from the smaller gametes. However, post-mating elimination of organelles derived from one gamete ensures uniparental inheritance, where the underlying mechanisms to distinguish organelles by their origin remain obscure.



全球贸易项目编号

货号GTIN
S1013-5G04061836844691
S1013-1G04061836831356