InChI key
LWZFANDGMFTDAV-WYDSMHRWSA-N
InChI
1S/C18H34O6/c1-2-3-4-5-6-7-8-9-10-11-16(21)23-13-15(20)18-17(22)14(19)12-24-18/h14-15,17-20,22H,2-13H2,1H3/t14-,15?,17+,18+/m0/s1
SMILES string
CCCCCCCCCCCC(=O)OC[C@@H](O)[C@H]1OC[C@H](O)[C@H]1O
description
non-ionic
mol wt
346.47 g/mol
greener alternative product characteristics
Use of Renewable Feedstocks
Learn more about the Principles of Green Chemistry.
sustainability
Greener Alternative Product
concentration
≥44% (GC)
greener alternative category
, Aligned
Quality Level
General description
我们致力于为您提供更环保的替代产品，以符合“绿色化学的 12 项原则”的一项或多项原则要求。本产品是100%的生物基非离子表面活性剂，因此符合“使用可再生原料”原则，属于我们绿色替代产品中的“12原则产品”。
Span 20是辅助表面活性剂。
Application
Span 20已用于评估伊曲康唑的增溶性和口服生物利用度的研究。 其还可用于研究水包油乳液中不饱和脂质的氧化。
Other Notes
脂肪酸组成：月桂酸（C12：0）≥44％；平衡主要是肉豆蔻酸（C14：0）、棕榈酸（C16：0）和亚麻酸（C18：3）酸。
Legal Information
Span is a registered trademark of Croda International PLC
存储类别
10 - Combustible liquids
wgk
WGK 1
flash_point_f
>300.2 °F - closed cup
flash_point_c
> 149 °C - closed cup
ppe
Eyeshields, Gloves, type N95 (US)
Claire Berton et al.
Journal of colloid and interface science, 377(1), 244-250 (2012-04-25)
The development of lipid oxidation in oil-in-water (O/W) emulsions is widely influenced by the properties of the interfacial layer, which separates the oil and water phases. In this work, the effect of the structure of the interface on the oxidative
Pao-Chu Wu et al.
Drug development and industrial pharmacy, 36(12), 1398-1403 (2010-06-16)
Nicardipine hydrochloride has been used widely for the treatment of angina pectoris and hypertension. Because of its extensive first pass metabolism after oral administration, the transdermal administration of nicardipine microemulsions was developed in this study. Microemulsions consisted of isopropyl myristate
Sinead Hickey et al.
International journal of pharmaceutics, 388(1-2), 213-222 (2009-12-17)
High-resolution ultrasonic spectroscopy was applied to analyse a pseudo-ternary phase diagram for a mixture consisting of water/ethyl oleate/Tween 80 and Span 20 at 25 degrees C. The measured changes in the ultrasonic velocity and attenuation with concentration of water in
Ingunn Tho et al.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 40(1), 25-32 (2010-02-23)
The objective of the study was to characterise the aqueous dispersions of ritonavir melt extrudates. More specifically to look into the particular system formed when melt extrudate of a poorly soluble drug dissolved in a hydrophilic polymer matrix containing a
Gabriela Calderó et al.
Journal of colloid and interface science, 353(2), 406-411 (2010-10-26)
Formation of polymeric O/W nano-emulsions has been studied in the water/polyoxyethylene 4 sorbitan monolaurate/ethylcellulose solution system by the phase inversion composition (PIC) method. These nano-emulsions were used for the preparation of nanoparticles by solvent evaporation. Composition variables such as O/S
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