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SAB1404625

Sigma-Aldrich

Monoclonal Anti-TNFRSF18 antibody produced in mouse

clone 2H4, purified immunoglobulin, buffered aqueous solution

别名:
GITR-D, AITR, GITR
NACRES:
NA.41

质量水平

100

生物来源

mouse

偶联物

unconjugated

抗体形式

purified immunoglobulin

antibody product type

primary antibodies

克隆

2H4, monoclonal

形式

buffered aqueous solution

分子量

antigen ~36.01 kDa

species reactivity

mouse, human

technique(s)

indirect ELISA: suitable
western blot: 1-5 μg/mL

同位素/亚型

IgG2bκ

NCBI登记号

UniProt登记号

运输

dry ice

储存温度

−20°C

Gene Information

human ... TNFRSF18(8784)

一般描述

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. (provided by RefSeq)

免疫原

TNFRSF18 (NP_004186, 26 a.a. ~ 115 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Sequence
QRPTGGPGCGPGRLLLGTGTDARCCRVHTTRCCRDYPGEECCSEWDCMCVQPEFHCGDPCCTTCRHHPCPPGQGVQSQGKFSFGFQCIDC

外形

Solution in phosphate buffered saline, pH 7.4

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存分类代码

13 - Non Combustible Solids

WGK

WGK 1

闪点(F)

Not applicable

闪点(C)

Not applicable

分析证书

原产地证书 (CofO)

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