SMB00073
岩白菜素
≥95% (LC/MS-ELSD)
别名:
Cuscutin, Ardisic acid B, Vakerin
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关于此项目
经验公式（希尔记法）:
C14H16O9
化学文摘社编号:
分子量:
328.27
UNSPSC Code:
12352205
PubChem Substance ID:
NACRES:
NA.25
MDL number:
产品名称
岩白菜素, ≥95% (LC/MS-ELSD)
SMILES string
O1[C@@H]2[C@H](OC(=O)c3c2c(c(c(c3)O)OC)O)[C@H]([C@@H]([C@H]1CO)O)O
InChI
1S/C14H16O9/c1-21-11-5(16)2-4-7(9(11)18)12-13(23-14(4)20)10(19)8(17)6(3-15)22-12/h2,6,8,10,12-13,15-19H,3H2,1H3/t6-,8-,10+,12+,13-/m1/s1
InChI key
YWJXCIXBAKGUKZ-HJJNZUOJSA-N
assay
≥95% (LC/MS-ELSD)
form
solid
application(s)
metabolomics
vitamins, nutraceuticals, and natural products
storage temp.
−20°C
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Biochem/physiol Actions
Bergenin displays antinociceptive and anti-inflammatory properties, in addition to its use in folk medicines as a potent hepatoprotective agent. Bergenin acts by inhibiting the formation of interleukin 1beta and TNF-α, which suggests its potential use for controling inflammatory pain.
General description
Natural product derived from plant source.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
Heitor A De Abreu et al.
Organic & biomolecular chemistry, 6(15), 2713-2718 (2008-07-18)
(+)-Bergenin (1) was isolated from Sacoglottis uchi, a species of vegetable found in the Amazon region and popularly used for the treatment of several hepatic problems. The structure of 1 was fully characterized using IR, GC-MS and NMR (1D and
Dong Wang et al.
Bioorganic & medicinal chemistry letters, 15(18), 4073-4075 (2005-07-05)
A novel C-C-coupled dimer derivative of bergenin was produced by the biotransformation of cultured mycelia of white rot fungus Pleurotus ostreatus. Its structure was elucidated by detailed spectroscopic analysis.
B Nyasse et al.
Die Pharmazie, 59(6), 492-494 (2004-07-14)
The presence of bergenin in substantial amounts in the methanol leaves extract of Flueggea virosa (Euphorbiaceae) was established as a strong chemotaxomic point of differentiation between Flueggea virosa and Securinega virosa. Bergenin showed an inhibitory effect on the growth of
Yan-Bin Shi et al.
Biomedical chromatography : BMC, 20(10), 1065-1070 (2006-04-04)
A validated reversed-phase high-performance liquid chromatographic (RP-HPLC) method was developed for the determination of bergenin in rat plasma. Bergenin in rat plasma was extracted with methanol, which also acted as a deproteinization agent. Chromatographic separation of bergenin was performed on
Shuang He et al.
Drug development and industrial pharmacy, 38(10), 1280-1288 (2011-12-31)
A novel coated gastric floating drug-delivery system (GFDDS) of bergenin (BN) and cetirizine dihydrochloride (CET) was developed. First, the pharmacodynamic studies were performed and the results revealed that the new compounds of bergenin/cetirizine dihydrochloride had comparative efficacy as commercial products
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