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45690
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PloS one, 7(4), e34475-e34475 (2012-04-10)
Photodynamic Therapy (PDT) involves the administration of a tumor localizing photosensitizing agent, which upon activation with light of an appropriate wavelength leads to the destruction of the tumor cells. The aim of the present study was to determine the efficacy
Journal of molecular recognition : JMR, 26(4), 181-189 (2013-03-05)
The present study aims to elucidate aspects of the protein binding ability of erythrosine B (ErB), a poly-iodinated xanthene dye and an FDA-approved food colorant (FD&C Red No. 3), which we have identified recently as a promiscuous inhibitor of protein-protein
Journal of the American Chemical Society, 133(51), 20680-20683 (2011-12-03)
We report the use of a simple complex assembled from Ni(II) salt and 2-mecaptoethanol in one step in water as the efficient catalyst in a molecular hydrogen system which can be sensitized by a low-cost xanthene dye, Erythrosin B. An
Bioscience, biotechnology, and biochemistry, 76(5), 870-874 (2012-06-29)
The xanthene dyes, erythrosine, phloxine, and rose bengal, were adsorbed to charred cellulose granules. The charred cellulose granules were preliminarily steeped in ionic (NaOH, NaCl, KOH, KCl, and sodium dodecyl sulfate (SDS)), nonionic (glucose, sucrose, and ethanol), and amphipathic sucrose
Biochimica et biophysica acta, 1828(2), 568-576 (2012-11-13)
Combination of fluorescence techniques and molecular docking was used to monitor interaction of Na,K-ATPase and its large cytoplasmic loop connecting fourth and fifth transmembrane helices (C45) with fluorone dyes (i.e. eosin Y, 5(6)-carboxyeosin, rose bengal, fluorescein, and erythrosine B). Our
Oral health & preventive dentistry, 10(3), 219-224 (2012-10-25)
To evaluate the efficacy of plaque removal of four different toothbrushes in visually disabled children. Three manual toothbrushes with different bristle designs (Oral-B CrossAction 40-regular, Oral-B ShinyClean 40-soft, Oral-B Advantage 40-soft) were compared with an electric toothbrush with an oscillating
BMC biotechnology, 11, 114-114 (2011-11-26)
Hemophilia A is a bleeding disorder caused by deficiency in coagulation factor VIII. Recombinant factor VIII (rFVIII) is an alternative to plasma-derived FVIII for the treatment of hemophilia A. However, commercial manufacturing of rFVIII products is inefficient and costly and
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 79(5), 889-897 (2011-05-10)
Xanthenes form to an important class of dyes which are widely used. Most of them present three acid-base groups: two phenolic sites and one carboxylic site. Therefore, the pKa determination and the attribution of each group to the corresponding pKa
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 50(10), 3447-3451 (2012-08-01)
Erythrosine (ErB) is a xanthene and an US Food and Drug Administration approved dye used in foods, drugs and cosmetics. Although its utilization is permitted, ErB is described as inhibitor of enzymes and protein-protein interactions and is toxic to pituitary
Biodegradation, 23(5), 725-737 (2012-03-23)
Biodegradation of a xanthene dyes was investigated for the first time using anaerobic granular sludge. On a first screening, biomass was able to decolorize, at different extents, six azo dye solutions: acid orange 7, direct black 19, direct blue 71
Photochemistry and photobiology, 88(3), 570-576 (2012-01-31)
The growing resistance to antibiotics has rendered antimicrobial photodynamic inactivation (PDI) an attractive alternative treatment modality for infectious diseases. Chitosan (CS) was shown to further potentiate the PDI effect of photosensitizers and was therefore used in this study to investigate
PloS one, 6(10), e25752-e25752 (2011-10-15)
Alzheimer's disease (AD) is the most common form of dementia. AD is a degenerative brain disorder that causes problems with memory, thinking and behavior. It has been suggested that aggregation of amyloid-beta peptide (Aβ) is closely linked to the development
Chemical & pharmaceutical bulletin, 60(7), 846-853 (2012-07-14)
The photodegradation of environmental mutagens, such as 3-amino-1,4-dimethyl-5H-pyrido[4,3-b]indole (Trp-P-1), 3-amino-1-methyl-5H-pyrido[4,3-b]indole (Trp-P-2), 2-amino-3-methyl-9H-pyrido[2,3-b]indole (MeAαC), and 2-amino-3-methyl-imidazo[4,5-f]quinoline (IQ), was investigated by visible irradiation in the presence of xanthene dyes as photosensitizers. Although the environmental mutagens themselves were very stable during visible irradiation
International journal of oral science, 4(4), 196-201 (2012-12-12)
The purpose of our study was to evaluate the effect of photodynamic therapy (PDT), using erythrosine as a photosensitizing agent and a dental halogen curing unit as a light source, on Streptococcus mutans in a biofilm phase. The S. mutans
ChemMedChem, 7(4), 571-577 (2012-02-23)
SecA is a central component of the general secretion system that is essential for bacterial growth and thus an ideal target for antimicrobial agents. A series of fluorescein analogues were first screened against the ATPase activity using the truncated unregulated
Reproductive biology and endocrinology : RB&E, 13, 64-64 (2015-06-19)
Bovine BSP5 is a multifunctional protein primarily involved in sperm capacitation. BSP5 consists of long N-terminal part followed by two similar and highly conserved fibronectin type II domains designated A and B. In order to assess the role of these
International journal of pharmaceutics, 423(1), 26-36 (2011-07-21)
Nanocrystalline calcium phosphate apatites constitute the mineral part of hard tissues, and the synthesis of biomimetic analogs is now well-mastered at the lab-scale. Recent advances in the fine physico-chemical characterization of these phases enable one to envision original applications in
Journal of photochemistry and photobiology. B, Biology, 106, 40-46 (2011-11-11)
Several photosensitizers have been used against oral bacteria without standardization. Singlet oxygen ((1)O(2)) is an aggressive chemical species that can kill cells through apoptosis or necrosis. to compare the antimicrobial activity of photodynamic therapy (PDT) with different photosensitizers at the
Pharmacology, 95(1-2), 78-86 (2015-01-31)
To evaluate antileishmanial activity of crotamine, a toxin isolated from Crotalus durissus terrificus, in solution form and encapsulated in biodegradable microparticles in vitro. Particles were analyzed on-chip by surface plasmon resonance and characterized by testing their diameters, zeta potential and
Carbohydrate research, 361, 120-126 (2012-09-29)
The effect of glycerol on molecular mobility and hydrogen bonding in amorphous glucose matrix was studied. Phosphorescence from erythrosin B (Ery B) was used to characterize the temperature dependence of mobility in glucose/glycerol films over the temperature range from 100
Chemosphere, 88(8), 974-979 (2012-04-10)
In this study, different concentrations of five food dyes (amaranth, patent blue, carminic acid, indigotine and erythrosine) have been evaluated for genotoxicity in the Somatic Mutation and Recombination Test (SMART) of Drosophila melanogaster. Standard cross was used in the experiment.
Mycoses, 55(1), 56-63 (2011-06-15)
The aim of this study was to evaluate the effects of photodynamic therapy (PDT) using rose bengal or erythrosine with light emitting diode (LED) on Candida albicans planktonic cultures and biofilms. Seven C. albicans clinical strains and one standard strain
Archives of oral biology, 56(11), 1299-1305 (2011-06-28)
The effect of erythrosine- and LED-mediated photodynamic therapy (PDT) on planktonic cultures and biofilms of Candida albicans and Candida dubliniensis was evaluated. Planktonic cultures of standardized suspensions (10(6)cells/mL) of C. albicans and C. dubliniensis were treated with erythrosine concentrations of
Journal of molecular biology, 413(3), 584-592 (2011-09-14)
The contractile and enzymatic activities of myosin VI are regulated by calcium binding to associated calmodulin (CaM) light chains. We have used transient phosphorescence anisotropy to monitor the microsecond rotational dynamics of erythrosin-iodoacetamide-labeled actin with strongly bound myosin VI (MVI)
Cytotechnology, 67(6), 1073-1084 (2014-05-07)
The aim of the study was to obtain the highest number of multipotent adipose-derived mesenchymal stem cells (ADMSCs) by using culture conditions which favour cell expansion without loss of mesenchymal stem cells (MSC)-like properties. Based on the assumption that stem
Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology, 11(6), 1010-1017 (2012-02-18)
In recent years, different methods and techniques have been applied to study the primary photophysical processes occurring in dye-loaded light-scattering powdered samples. In spite of this, there are still no reliable methods for the determination of triplet quantum yields for
PloS one, 9(10), e109901-e109901 (2014-10-22)
The gold(I) mixed-ligand complexes involving O-substituted derivatives of 9-deazahypoxanthine (HLn) and triphenylphosphine (PPh3) with the general formula [Au(Ln)(PPh3)] (1-5) were prepared and thoroughly characterized by elemental analysis, FT-IR and multinuclear NMR spectroscopy, ESI+ mass spectrometry, single crystal X-ray (HL5 and
Clinica chimica acta; international journal of clinical chemistry, 413(13-14), 1087-1091 (2012-04-03)
In spite of the urgent necessity for a screening test of urinary protein for the early diagnosis of kidney diseases, a rapid, accurate and cost-effective method for their detection has yet to be developed. A solution containing a buffer agent
Oral surgery, oral medicine, oral pathology and oral radiology, 114(1), 67-74 (2012-06-26)
This study evaluated the effects of photodynamic therapy (PDT) on buccal candidiasis in mice and on the adherence of yeast to buccal epithelial cells (BECs) in vitro. A total of 56 immunosuppressed mice with buccal candidiasis were subjected to PDT
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