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Nicola Ciliberti et al.
Phytopathology, 105(3), 325-333 (2014-10-30)
The effect of temperature and wetness duration on infection of Vitis vinifera inflorescences (from "inflorescence clearly visible" to "end of flowering" stages) and young berry clusters (at "fruit swelling" and "berries groat-sized" stages) by Botrytis cinerea was investigated. Artificial inoculations
Daniela Michlmayr et al.
Journal of virology, 88(17), 9553-9567 (2014-06-06)
The encephalitic response to viral infection requires local chemokine production and the ensuing recruitment of immune and inflammatory leukocytes. Accordingly, chemokine receptors present themselves as plausible therapeutic targets for drugs aimed at limiting encephalitic responses. However, it remains unclear which
V P Stankov-Jovanović et al.
Journal of pharmaceutical and biomedical analysis, 111, 78-90 (2015-04-12)
Extracts of different polarity obtained from various plant parts (root, leaf, flower and fruit) of Seseli rigidum were studied by different antioxidant assays: DPPH and ABTS radical scavenging activity, by total reducing power method as well as via total content
Mehdi Mirzaei et al.
Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging, 17(6), 770-776 (2015-04-29)
Early stage prostate cancer diagnosis is of high global interest. Magnetic resonance imaging (MRI) is a non-invasive modality for early cancer diagnosis, in particular for prostate cancer detection. The research aim is to synthesize a nanodendrimer and its conjugate with
Jingming Li et al.
Journal of diabetes research, 2015, 963289-963289 (2015-04-14)
NADPH oxidase 4 (Nox4) is a major isoform of NADPH oxidase in retinal endothelial cells. Our previous study suggests that upregulation of Nox4 in retinal endothelial cells contributes to retinal vascular leakage in diabetes. In the current study, we investigated
Ganapathi Raj Murugesan et al.
Journal of the science of food and agriculture, 95(12), 2521-2527 (2014-11-05)
Efficacy of a multi-strain direct-fed microbial product (PoultryStar(®) ME; PS) and a xylanase enzyme product on the dietary energy utilization efficiency and resulting performance in broiler chickens was evaluated. Apart from performance parameters, cecal and serum metabolites and activities of
Takumi Yamane et al.
Bioscience, biotechnology, and biochemistry, 79(2), 185-189 (2014-11-25)
The effects of modern dressings on inflammation, which represent the earliest phase of wound healing, are poorly understood. We investigated the effects of modern hydrocellular foam dressings (HCFs) on wound healing and on the gene expression levels of the inflammatory
Danielle E Fortune et al.
Infection and immunity, 82(8), 3186-3198 (2014-05-21)
Decorin-binding protein A (DbpA) of Borrelia burgdorferi mediates bacterial adhesion to heparin and dermatan sulfate associated with decorin. Lysines K82, K163, and K170 of DbpA are known to be important for in vitro interaction with decorin, and the DbpA structure
Liang Ma et al.
Cell research, 25(1), 24-38 (2014-10-25)
Cells communicate with each other through secreting and releasing proteins and vesicles. Many cells can migrate. In this study, we report the discovery of migracytosis, a cell migration-dependent mechanism for releasing cellular contents, and migrasomes, the vesicular structures that mediate
Abderrahmane Kaidi et al.
Nature, 498(7452), 70-74 (2013-05-28)
The detection of DNA lesions within chromatin represents a critical step in cellular responses to DNA damage. However, the regulatory mechanisms that couple chromatin sensing to DNA-damage signalling in mammalian cells are not well understood. Here we show that tyrosine
Erika L Pfaunmiller et al.
Journal of chromatography. A, 1366, 92-100 (2014-09-30)
One-site immunometric assays that utilize affinity microcolumns were developed and evaluated for the analysis of protein biomarkers. This approach used labeled antibodies that were monitored through on-line fluorescence or near-infrared (NIR) fluorescence detection. Human serum albumin (HSA) was utilized as
Nicholas A Bedard et al.
The Journal of arthroplasty, 29(10), 1961-1969 (2014-06-19)
Long term total hip arthroplasty follow-up has demonstrated bearing surface wear and failure of fixation as the major modes of failure. The purpose of this study was to evaluate the minimum 10year results of a third generation cementless acetabular component
Dan-ju Tso et al.
Journal of molecular biology, 426(10), 2112-2129 (2014-03-25)
The G-loop is a 10-residue glycine-rich loop that protrudes from the surface of the mature bacteriophage HK97 capsid at the C-terminal end of the long backbone helix of major capsid protein subunits. The G-loop is essential for assembly, is conserved
Oday Alsarraf et al.
Experimental eye research, 127, 124-131 (2014-07-30)
Neuroretinal ischemic injury contributes to several degenerative diseases in the eye and the resulting pathogenic processes involving a series of necrotic and apoptotic events. This study investigates the time and extent of changes in acetylation, and whether this influences function
Augusta Pisanu et al.
Neuropharmacology, 89, 398-411 (2014-12-03)
Microdialysis during i.v. drug self-administration (SA) have implicated nucleus accumbens (NAc) shell DA in cocaine and heroin reinforcement. However, this correlative evidence has not been yet substantiated by experimental evidence obtained by studying the effect of selective manipulation of NAc
Raquel Liébana et al.
Biofouling, 31(1), 71-82 (2015-01-15)
The yeast community was studied in a municipal full-scale membrane bioreactor wastewater treatment plant (MBR-WWTP). The unexpectedly high diversity of yeasts indicated that the activated sludge formed a suitable environment for them to proliferate, with cellular concentrations of 2.2 ±
Song P Seto et al.
Bioconjugate chemistry, 26(2), 286-293 (2015-01-27)
Bone morphogenetic protein-2 (BMP-2) plays an important role in bone and cartilage formation and is of interest in regenerative medicine. Heparin can interact electrostatically with BMP-2 and thus has been explored for controlled release and potential stabilization of this growth
Wenying Fan et al.
Journal of chromatography. A, 1418, 36-44 (2015-10-05)
Graphene oxide (GO) is an ideal adsorbent for polar and less polar compounds due to its hexagonal carbon network structure with oxygen-containing groups, while its strong hydrophilicity and water solubility limited its application in sample pretreatment techniques. Herein, GO was
Zhaoxia Qian et al.
ACS nano, 9(2), 1263-1270 (2015-01-27)
We report a synthetic approach to produce raspberry-like plasmonic nanostructures with unusually strong magnetic resonances, termed raspberry-like metamolecules (raspberry-MMs). The synthesis based on the surfactant-assisted templated seed-growth method allows for the simultaneous one-step synthesis and assembly of well-insulated gold nanoparticles.
Toshie Takahashi et al.
Lipids, 49(9), 905-917 (2014-08-12)
It has been recognized that human hair lipids play crucial roles in the integrity of cells and matrices, while the details of distribution and structure of the minor lipids are hardly known. Here we investigated the lipids at the hair
Jennifer A Hetz et al.
Molecular and cellular endocrinology, 411, 38-48 (2015-04-22)
Maturation of the mammalian growth axis is thought to be linked to the transition from fetal to post-natal life at birth. However, in an altricial marsupial, the tammar wallaby (Macropus eugenii), this process occurs many months after birth but at
Jyrki Heinämäki et al.
International journal of pharmaceutics, 489(1-2), 91-99 (2015-05-06)
We showed that the addition of suberin fatty acids (SFAs) even at small concentrations significantly improves the water vapor barrier properties of hydroxypropyl methylcellulose (HPMC) films. SFAs were isolated from the outer birch bark using extractive hydrolysis. The effects of
Brian K Jones et al.
Journal of biomechanics, 48(14), 3945-3949 (2015-10-17)
The frictional response of whole human joints over durations spanning activities of daily living has not been reported previously. This study measured the friction of human glenohumeral joints during 24 h of reciprocal loading in a pendulum testing device, at
Amira M El-Kosasy et al.
Talanta, 143, 402-413 (2015-06-17)
Four native fluorescence methods were suggested for simultaneous determination of amlodipine (AML) and valsartan (VAL). These methods were based on excitation of both drugs at λ(ex) 300 nm, in one step, to give maximum emission at λ(em) 378 and 496
Qingqing Cao et al.
PloS one, 10(7), e0134713-e0134713 (2015-08-01)
Wetland ecosystems are represented as a significant reservoir of organic carbon and play an important role in mitigating the greenhouse effect. In order to compare the compositions and distribution of organic carbon in constructed and natural river wetlands, sediments from
Wei Chen et al.
Molecular medicine reports, 12(5), 7712-7720 (2015-10-16)
A previous nationwide Chinese epidemiological study revealed through isolation of A‑B+ Clostridium difficile strains, which produce toxin B (TcdB), but not toxin A TcdA, that the strains are widespread and more frequent in east Asian countries,. The development of a
Jee-Yeon Hwang et al.
Journal of molecular biology, 426(20), 3454-3466 (2014-08-12)
The gene silencing transcription factor REST [repressor element 1 silencing transcription factor]/NRSF (neuron-restrictive silencer factor) actively represses a large array of coding and noncoding neuron-specific genes important to synaptic plasticity including miR-132. miR-132 is a neuron-specific microRNA and plays a
Siqingaowa Suo et al.
Virus genes, 51(1), 51-56 (2015-05-28)
The spike (S) protein of porcine transmissible gastroenteritis virus (TGEV) is located within the viral envelope and is the only structural protein that possesses epitopes capable of inducing virus-neutralizing antibodies. Among the four N-terminal antigenic sites A, B, C, and
Kai Wang et al.
Journal of biomedical materials research. Part A, 103(9), 2839-2846 (2015-02-19)
Bovine serum albumin has been PEGylated and glycosylated to create mimetic materials for the extracellular matrix (ECM) with potential tissue engineering applications. Different surfaces for cell adhesion were achieved by crosslinking the initial albumin product and forming either a coating
Marzieh Rashidipour et al.
Journal of AOAC International, 97(4), 1109-1113 (2014-08-26)
Matrix solid-phase dispersion (MSPD) methodology as a quick and easy extraction method has been developed to extract oleuropein from Olea europaea leaves. This method has been compared with conventional maceration and Soxhlet extraction (SOXE) methods. Variables affecting MSPD, such as
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