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77367
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关键词:'77367'
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Mayumi Bowen et al.
Journal of pharmaceutical sciences, 101(12), 4433-4443 (2012-09-25)
Developing high-concentration monoclonal antibody (mAb) liquid formulations for subcutaneous (s.c.) administration is challenging because increased viscosity makes injection difficult. To overcome this obstacle, we investigated a nonaqueous powder suspension approach. Three IgG1 mAbs were spray dried and suspended at different
Kelley A Distel et al.
Bioresource technology, 96(5), 617-623 (2004-10-27)
Proleather from Bacillus sp. was chemically modified with decanoyl chloride for enhanced activity for the preparation of poly(lactic acid) in organic solvents. The modified enzyme was highly soluble (up to 44 mg-protein/ml) and active in various organic solvents including chloroform
Chiaki Inaba et al.
Applied microbiology and biotechnology, 83(5), 859-864 (2009-03-17)
The whole-cell biocatalyst displaying Candida antarctica lipase B (CALB) on the yeast cell surface with alpha-agglutinin as the anchor protein was easy to handle and possessed high stability. The lyophilized CALB-displaying yeasts showed their original hydrolytic activity and were applied
Yuanyuan Sun et al.
Journal of environmental quality, 38(4), 1591-1597 (2009-06-25)
A new approach using aqueous ethyl lactate-modified [S,S]-ethylenediaminedisuccinic acid (EDDS) washing solutions was examined in the laboratory for the simultaneous removal of phenanthrene, pyrene, and Cu from contaminated soils. Ethyl lactate demonstrated greater solubilization efficiency for phenanthrene and pyrene than
Reductive dechlorination of tetrachloroethene by a mixed bacterial culture growing on ethyl lactate.
Jayashree Jayaraj et al.
Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering, 39(6), 1399-1414 (2004-07-13)
Chloroethenes like tetrachloroethene (PCE) are the most prevalent groundwater contaminants in the USA. Their presence as nonaqueous phase liquids (NAPLs) makes remediation difficult. Among options for NAPL cleanup, co-solvent injection has demonstrated success. However, the process has the potential to
Elisabetta Ranucci et al.
Macromolecular bioscience, 4(8), 706-713 (2004-10-07)
1-Vinyl-2-pyrrolidinone (VP) oligomers bearing a lactate group at one end (PVP-L) were obtained by chain-transfer controlled radical polymerisation carried out in the presence of ethyl L-lactate as chain-transfer agent (CTA). Their number-average molecular weights were in the range 1500-4000 with
Jun Liu et al.
The Journal of organic chemistry, 77(21), 9718-9723 (2012-10-12)
The efficient and concise synthesis of (-)-orthodiffenes A and C has been accomplished for the first time in eight steps from readily available chiral synthons, D-mannose and D-ethyl lactate. Our work confirmed the complete structure of orthodiffenes A and C
L Zhong et al.
Journal of hazardous materials, 244-245, 160-170 (2012-12-19)
Xanthan gum solutions are shear thinning fluids which can be used as delivery media to improve the distribution of remedial amendments injected into heterogeneous subsurface environments. The rheological behavior of the shear thinning solution needs to be known to develop
O Dudeck et al.
AJNR. American journal of neuroradiology, 27(9), 1900-1906 (2006-10-13)
The organic solvent dimethyl-sulfoxide (DMSO), as a commonly used vehicle for nonadhesive liquid embolics, is not devoid of local angiotoxic effects. We compared microvascular toxicities of superselective infusions of DMSO with potentially more compatible solvents in swine rete mirabile. Fourteen
Eduardo S P Nascimento et al.
Journal of agricultural and food chemistry, 56(14), 5488-5493 (2008-06-24)
An analytical procedure for the separation and quantification of ethyl acetate, ethyl butyrate, ethyl hexanoate, ethyl lactate, ethyl octanoate, ethyl nonanoate, ethyl decanoate, isoamyl octanoate, and ethyl laurate in cachaca, rum, and whisky by direct injection gas chromatography-mass spectrometry was
Ya-xin Lu et al.
Yao xue xue bao = Acta pharmaceutica Sinica, 42(4), 445-449 (2007-07-18)
To study the rheological properties of sucrose acetate isobutyrate (SAIB) in situ gel and the influencing factors. Measurements of shear stress and viscosity were carried out at different shear rate. The rheological properties of SAIB solution were similar to those
Roberto Rodríguez Madrera et al.
Journal of the science of food and agriculture, 91(5), 797-804 (2011-03-09)
Fresh cider spirits are alcoholic beverages mainly constituted by volatile compounds from apples that are formed during fermentation or generated during distillation. In this study the chemical and sensory changes that take place during the maturation of fresh cider spirits
Marcus Hollenbach et al.
Biochemical pharmacology, 76(5), 631-644 (2008-07-16)
Esters of alpha-oxo-carbonic acids such as ethyl pyruvate (EP) have been demonstrated to exert inhibitory effects on the production of anti-inflammatory cytokines. So far, there is no information about effects, if any, of ethyl lactate (EL), an obviously inactive analogue
Hongyan Guo et al.
Journal of hazardous materials, 174(1-3), 59-63 (2009-09-29)
A new approach using aqueous ethyl lactate-modified [S,S]-ethylenediaminedisuccinic acid (EDDS) washing solutions for the removal of Cu from field-contaminated soils was examined in the laboratory. At pH 7 the maximum extraction efficiencies of Cu were about 41% by EDDS solution
Colin Bonduelle et al.
Chemistry (Weinheim an der Bergstrasse, Germany), 14(17), 5304-5312 (2008-05-01)
Model reactions for the 4-dimethylaminopyridine (DMAP)-catalyzed ring-opening polymerization of lactide and the corresponding lactic O-carboxylic anhydride (lacOCA) have been studied computationally at the B3LYP/6-31G(d) level of theory. The solvent effect of dichloromethane was taken into account through PCM/SCRF single-point calculations
Sulette Malherbe et al.
Journal of industrial microbiology & biotechnology, 39(3), 477-494 (2011-11-29)
In this research work we investigated changes in volatile aroma composition associated with four commercial Oenococcus oeni malolactic fermentation (MLF) starter cultures in South African Shiraz and Pinotage red wines. A control wine in which MLF was suppressed was included.
Jimmy T Liang et al.
The Journal of organic chemistry, 72(22), 8243-8250 (2007-09-25)
Development of efficient, scalable routes for the synthesis of (S)-3-[5-(3,4-dichlorophenyl)-1-(4-methoxyphenyl)-1H-pyrazol-3-yl]-2-m-tolyl propionic acid, a selective cholecystokinin 1 (CCK 1) receptor antagonist, is described. A key feature of the scale-up route is a concise construction of the complete pyrazole framework in a
Francisco Pérez-Mendoza et al.
FEMS yeast research, 5(6-7), 685-690 (2005-03-23)
Thirty-nine yeasts isolated from apple, grape and cane juices were screened for their oxidoreductase activity. The two strains of Pichia, one isolated from apple and one from cane juices, appear to be promising strains for oxidoreductase activity on alpha-oxoesters. They
Salvatore Guarino et al.
Pest management science, 67(1), 77-81 (2010-10-19)
The red palm weevil (RPW), Rhynchophorus ferrugineus Olivier, accidentally introduced into the European countries facing the Mediterranean basin, is becoming the most serious pest for ornamental palms in the urban environment. In the present work, tests were conducted on the
Filip de Clippel et al.
Journal of the American Chemical Society, 134(24), 10089-10101 (2012-05-04)
A novel catalyst design for the conversion of mono- and disaccharides to lactic acid and its alkyl esters was developed. The design uses a mesoporous silica, here represented by MCM-41, which is filled with a polyaromatic to graphite-like carbon network.
Chiew Lin Yap et al.
Journal of environmental sciences (China), 24(6), 1064-1075 (2012-01-01)
Solubility data of recalcitrant contaminants in cosolvents is essential to determine their potential applications in enhanced soil remediation. The solubilities of phenanthrene, anthracene, fluoranthene and benzo[a]pyrene in ethyl lactate/water and ethanol/water mixtures were measured using equilibrium techniques. The cosolvency powers
Marc R Elie et al.
Journal of hazardous materials, 248-249, 150-158 (2013-01-29)
The present study evaluates the capability of an activated-magnesium metal and protic co-solvents to promote the reductive degradation of three different polycyclic aromatic hydrocarbons, specifically pyrene, benzo[k]fluoranthene and benzo[g,h,i]perylene. Multivariate analyses demonstrated that the kinetics of degradation was affected by
Riccardo Levato et al.
Macromolecular bioscience, 12(4), 557-566 (2012-03-01)
PLA MPs are prepared via a novel and toxic-chemical-free fabrication route using ethyl lactate, a green solvent and FDA-approved aroma. MPs are obtained by a solution jet break-up and solvent displacement method. Adjusting flow parameters allows the tuning of MPs
Betty K Ishida et al.
Journal of agricultural and food chemistry, 57(3), 1051-1059 (2009-01-14)
Few environmentally friendly solvents are available to extract carotenoids for use in foods. The most effective known solvents are products of the petroleum industry and toxic for human consumption. Yet carotenoid extracts are desirable for use in dietary supplements and
Jiahua Li et al.
Journal of hazardous materials, 181(1-3), 673-678 (2010-06-18)
In order to explore a practical approach to the remediation of the cadmium (Cd)-contaminated soil in the lower reaches of the Yangtze River, we evaluated the effects of a local willow (Salix x aureo-pendula CL 'J1011') of absorbing, accumulating, and
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