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Yuebiao Zhou et al.
Journal of the American Chemical Society, 140(48), 16842-16854 (2018-11-18)
The first broadly applicable strategy for SN2″-selective and enantioselective catalytic substitution is disclosed. Transformations are promoted by 5.0 mol% of a sulfonate-containing NHC-Cu complex (NHC = N-heterocyclic carbene), and are carried out in the presence of commercially available allenyl-B(pin) (pin
Sarawut Oo-Puthinan et al.
Biochimica et biophysica acta, 1780(2), 89-100 (2007-12-07)
Binding specificities of mouse macrophage galactose-type C-type lectin 1 (MGL1/CD301a) and 2 (MGL2/CD301b) toward various oligosaccharides were compared by frontal affinity chromatography. MGL1 preferentially bound oligosaccharides containing Lewis(X) (Le(X)) trisaccharides among 111 oligosaccharides tested, whereas MGL2 preferentially bound globoside Gb4.
Maria J Garcia-Velloso et al.
European radiology, 27(8), 3190-3198 (2016-12-23)
Our aim was to evaluate the diagnostic accuracy of magnetic resonance imaging (MRI) fused with prone 2-[fluorine-18]-fluoro-2-deoxy-D-glucose (FDG) positron emission tomography (PET) in primary tumour staging of patients with breast cancer. This retrospective study evaluated 45 women with 49 pathologically
J Hall et al.
Biochemistry, 28(6), 2568-2571 (1989-03-21)
The reaction of Rhodobacter sphaeroides cytochrome c2 with the Rb. sphaeroides cytochrome bc1 complex was studied by using singly labeled cytochrome c2 derivatives. Cytochrome c2 was treated with chlorodinitrobenzoic acid to modify lysine amino groups to negatively charged carboxydinitrophenyllysines and
Wendy Pollock et al.
Journal of immunological methods, 347(1-2), 19-23 (2009-06-06)
Most laboratories screen for antineutrophil cytoplasmic antibodies (ANCA) with indirect immunofluorescence (IIF) and confirm cytoplasmic (C-ANCA) and perinuclear (P-ANCA) staining with ELISAs for proteinase 3 (PR3) and myeloperoxidase (MPO) specificities. This study determined the concordance of ANCA test results from
Loreta Levinskaite
Annals of agricultural and environmental medicine : AAEM, 19(1), 85-89 (2012-04-03)
Microscopic fungi are able to contaminate and deteriorate various food products and can subsequently cause health problems. Long usage of the same preservatives and disinfectants against spoilage fungi may lead to the development of fungal resistance to those chemicals. The
Tasneem Asghar et al.
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 20(2), 59-63 (2005-04-13)
Endometriosis is a complex trait, which means that multiple susceptibility genes interact with one another and the environment to produce the phenotype. One of the genes previously implicated in the disease is CYP17; this encodes the enzyme P450c17alpha, which plays
Blady Lopez-Alvarez et al.
Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering, 47(13), 2141-2150 (2012-08-09)
The degradation of the pesticide carbofuran (CBF) using solar photo-Fenton treatment, at both the laboratory and the pilot scale, was evaluated. At the laboratory scale, in a suntest reactor, the Fe(2+) concentration and H(2)O(2) concentration were evaluated and optimized using
K E Snider et al.
The Journal of clinical endocrinology and metabolism, 98(2), E355-E363 (2013-01-01)
Hypoglycemia due to congenital hyperinsulinism (HI) is caused by mutations in 9 genes. Our objective was to correlate genotype with phenotype in 417 children with HI. Mutation analysis was carried out for the ATP-sensitive potassium (KATP) channel genes (ABCC8 and
Hemin Chin et al.
Experimental & molecular medicine, 38(2), 144-152 (2006-05-05)
We have previously isolated a novel protein "B/K" that contains two C2-like domains. Here, we report the isolation and mRNA distribution of a human B/K isoform, and protein kinase A (PKA)-dependent phosphorylation of the B/K protein. The 1.5 kb human
H M Lamb et al.
Drugs, 56(6), 1047-1052 (1999-01-08)
Pexiganan acetate (MSI 78) is a synthetic cationic peptide (22 amino acids) with antibacterial activity. It is an analogue of magainin 2, which is a host defence peptide isolated from frog skin. The drug is thought to act by disturbing
Yi-Jun Zhang et al.
EBioMedicine, 28, 62-69 (2018-02-06)
SATB2 (Special AT-rich sequence-binding protein 2) has recently been shown to be a specific biomarker of colorectal cancer (CRC). The aim of this study was to investigate the diagnostic potential of SATB2 as a means of detecting a CRC origin
Babasaheb P Bandgar et al.
Bioorganic & medicinal chemistry letters, 20(7), 2292-2296 (2010-03-09)
A series of nitrogen-containing benzophenone analogues were synthesized by Mannich reaction and evaluated for the inhibition of pro-inflammatory cytokines, TNF-alpha and IL-6. DPPH (1,1-diphenyl-2-picryl hydrazine) radical scavenging activity and its kinetics were studied to determine the antioxidant potential of the
Eun-Kyung Kim et al.
Journal of agricultural and food chemistry, 52(2), 196-200 (2004-01-22)
Corn silage was dried, ground, and then extracted with 0.1 M ethylenediaminetetraacetic acid. The filtrate was applied to a FumoniTest immunoaffinity column. Fumonisins were derivatized with naphthalene-2,3-dicarboxaldehyde, separated on a C(18) liquid chromatographic column, and detected by fluorescence. The detection
Sabine C Glöckner et al.
Cancer research, 69(11), 4691-4699 (2009-05-14)
We have used a gene expression array-based strategy to identify the methylation of tissue factor pathway inhibitor 2 (TFPI2), a potential tumor suppressor gene, as a frequent event in human colorectal cancers (CRC). TFPI2 belongs to the recently described group
G E Hanks et al.
International journal of radiation oncology, biology, physics, 13(4), 499-505 (1987-04-01)
This report extends the follow-up of patients studied in the Patterns of Care Survey of Prostate Cancer treated in the United States between 1973 and 1975 from a maximum of 5 years to a maximum of 10 years. Survival for
Chia-Yuan Chang et al.
Bioresource technology, 102(9), 5325-5330 (2010-12-31)
This study investigated the feasibility and the treatment efficiency of a cyclic anoxic/aerobic two-stage MBR for treating polymeric industrial wastewater. The anoxic/aerobic hybrid MBR was operated without sludge withdrawal except sampling during the study. The results showed that the highest
Michelangelo Pascale et al.
Journal of food protection, 74(10), 1700-1707 (2011-10-19)
The effect of processing on mycotoxin content in milling fractions has been investigated in 10 samples of durum wheat contaminated with T-2 and HT-2 toxins at levels ranging from 97 to 5,954 μg/kg (sum of T-2 and HT-2 toxins). Either
Luis Pedro Coelho et al.
Bioinformatics (Oxford, England), 31(14), 2364-2370 (2015-03-21)
Neutrophil extracellular traps (NETs) are believed to be essential in controlling several bacterial pathogens. Quantification of NETs in vitro is an important tool in studies aiming to clarify the biological and chemical factors contributing to NET production, stabilization and degradation.
Punit Sharma et al.
Clinical nuclear medicine, 40(7), e351-e356 (2015-03-19)
The aim of this study was to evaluate the role of ⁶⁸Ga DOTANOC PET/CT imaging in patients with multiple endocrine neoplasia (MEN) syndromes. Data of 33 patients (age, 33.5 [13.8] years; male 14/female 19) with MEN syndromes (MEN 1, 9;
J Lourtet-Hascoët et al.
International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 51, 56-61 (2016-10-26)
The aim of this study was to assess the characteristics of periprosthetic joint infection (PJI) due to Staphylococcus lugdunensis and to compare these to the characteristics of PJI due to Staphylococcus aureus and Staphylococcus epidermidis. A retrospective multicentre study including
Angela Beaton et al.
Cell and tissue research, 311(2), 207-215 (2003-02-22)
The protein synthesis inhibitor cycloheximide (Chx) suppresses prolactin-induced beta-casein gene expression in the mammary epithelial cell line COMMA-D. As the mechanism underlying this effect is unclear, the effects of protein synthesis inhibitors on interactions of transcription factors with the beta-casein
K J Elliott et al.
Journal of molecular neuroscience : MN, 7(3), 217-228 (1996-10-01)
cDNA clones encoding human neuronal nicotinic acetylcholine receptor alpha 2, alpha 3, alpha 4, alpha 5, alpha 6, alpha 7, beta 2, beta 3, and beta 4 subunits were isolated from brainstem, hippocampus, prefrontal cortex, substantia nigra, thalamus, and IMR32
C Kaiser et al.
Journal of medicinal chemistry, 25(6), 697-703 (1982-06-01)
Resolution of the unique dopamine receptor agonist 2,3,4,5-tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine (1) was achieved by a stereospecific multistep conversion of the readily separated enantiomers of its O,O,N-trimethylated precursor 2. The absolute stereochemistry of the antipodes of 2-MeI was determined by single-crystal X-ray diffractometric
Ling Yeung et al.
Acta ophthalmologica, 88(7), 753-758 (2009-11-03)
This study aimed to examine the correlation between glycosylated haemoglobin (HbA1c) level and macular volume in diabetes patients without diabetic macular oedema (DMO). We carried out an observational, cross-sectional study. Patients who had diabetes mellitus (DM) of ≥ 10 years
María Ibáñez et al.
Journal of chromatography. A, 1081(2), 145-155 (2005-07-26)
This paper describes a method for the sensitive and selective determination of glyphosate, glufosinate and aminomethylphosphonic acid (AMPA) residues in water and soil samples. The method involves a derivatization step with 9-fluorenylmethylchloroformate (FMOC) in borate buffer and detection based on
Yun Liu et al.
International journal of nanomedicine, 11, 1147-1158 (2016-04-05)
To compare the direct osteogenic effect between placental growth factor-2 (PlGF-2) and bone morphogenic protein-2 (BMP-2). Three groups of PlGF-2/BMP-2-loaded heparin-N-(2-hydroxyl) propyl-3-trimethyl ammonium chitosan chloride (HTCC) nanocomplexes were prepared: those with 0.5 μg PlGF-2; with 1.0 μg BMP-2; and with
Yoshiaki Oshima et al.
Masui. The Japanese journal of anesthesiology, 54(8), 875-880 (2005-08-18)
Continuous epidural administration of droperidol at 2.5 mg x day(-1) or less was performed in 837 patients after surgery. In 4 of these patients, an extrapyramidal reaction occurred. Patient 1 was a 10-year-old girl who developed the symptom 29 hours
Barbara Wusk et al.
European journal of clinical pharmacology, 60(1), 5-10 (2004-02-27)
More than 11% of the Caucasian population are heterozygous or homozygous carriers of thiopurine S-methyltransferase (TPMT) mutants and are at risk for toxic side effects when treated with thiopurine drugs. Therefore, screening for TPMT polymorphisms in a patient prior to
Sylwia Mozia et al.
Materials (Basel, Switzerland), 13(11) (2020-06-14)
This paper describes the investigations on the possibilities of treatment of wastewater generated in an industrial laundry with application of a combined biological-photooxidation- membrane system aimed at water recycle and reuse. The two treatment schemes were compared: 1) scheme A
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