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Building Regional Cell Culture Media Supply Chains

Ensure reliable cell culture media supply with our continuously expanding global network of regional sites for resilient biopharma manufacturing.

PROTAC Synthesis Kits for Targeted Protein Degradation

Discover QuicTPD™ Acid/Amine Screening Sets for rapid, high-throughput PROTAC® synthesis, streamlining targeted protein degradation research.

Developing and Manufacturing Attenuated Viral Vaccines

Learn more one the attenuated viral vaccines manufacturing process: cell culture, clarification, nuclease treatment, chromatography, and sterile filtration.

Manufacturing Strategies for mRNA Vaccines and Therapeutics

mRNA technology offers therapeutic versatility; its delivery systems induce protein production for various applications.

Transforming the Biopharma Supply Chain and Analytics Capabilities with eData

An essential step in the progress towards Pharma 4.0 is the conversion of paper-based data to an electronic format, allowing it to be transferred, received, and available at the right time, in the right place, by those who need it.

mRNA 疫苗和疗法的生产策略

mRNA 技术具有多种治疗功能；其输送系统可诱导蛋白质的产生，从而实现各种应用。

Workflow for the Analysis of Polysorbate 80 in Erbitux® Formulation

A complete reversed phase HPLC-ELSD workflow, including sample preparation for the analysis of Polysorbate 80 in a monoclonal antibody formulation.

An Introduction to Antibodies: Antibody-Antigen Interaction

The strength of interaction between antibody and antigen at single antigenic sites can be described by the affinity of the antibody for the antigen.

Antibody Standard Validation

Explore antibody validation, including antibody and target, species validation, lot validation, application validation, storage and handling, citations, and quality control, in detail.

An Introduction to Antibodies: Antigens, Epitopes and Antibodies

Antibodies combine with specific antigens to generate an exclusive antibody-antigen complex. Learn about the nature of this bond and its use as a molecular tag for research.

Protein Conformation Array Multiplexing

Monoclonal antibodies (mAbs) lead biologics growth, predicted $125 billion worldwide sales by 2020, emphasizing their therapeutic significance.

Conferma^® ELISAs: Designed for Sample Detection & Lot Consistency

Learn about the Conferma® ELISA development and manufacturing methods that provide strong sample detection and long-term assay and lot consistency, giving you confidence in your research.

ELISA Troubleshooting Guide

Troubleshoot and optimize ELISAs using this guide that includes solutions to some of the most common sources of problems for assay development.

ELISpot Assay: Functional Cellular Immunology

ELISpot assay provides qualitative and quantitative information on immune responses, visualizing multiple secretory products from single responding cells.

Antibody Generation | Monoclonal vs Polyclonal Antibodies

Learn differences in monoclonal vs polyclonal antibodies including how antibodies are generated, clone numbers, and antibody formats.

A Highly Sensitive IFN-γ ELISpot Assay to Quantify Cellular Immune Responses to Previous Viral Infection

This study presents an example of a typical ELISpot assay for quantifying the number of pre-existing, antigen-reactive T cells from peripheral blood mononuclear cell (PBMC) samples obtained from donors previously infected with cytomegalovirus (CMV).

Secondary Antibodies, Conjugates, and Kits

Technical Support for Secondary Antibodies, Conjugates, and Kits

How to Work with Enzymes Supplied as Ammonium Sulfate Suspensions

Instructions for working with enzymes supplied as ammonium sulfate suspensions

Aprotinin

While aprotinin and bovine pancreatic trypsin inhibitor (BPTI) are the same protein sequence, the term aprotinin is typically used when describing the protein derived from bovine lung.

Enzymatic Method for Determining Branched Chain Amino Acids (BCAA Assay)

Assay protocol for the colorimetric detection of Branched Chain Amino Acids (BCAA) in biological samples using the alanine assay kit.

Glycobiology - Carbohydrate Enzymes and Proteins

Explore our complex carbohydrate proteins, enzyme products and kits for investigating oligosaccharides, polysaccharides, and numerous additional aspects of your carbohydrate workflow.

Cholesterol Esterification

Cholesterol esterification enhances transport efficiency in lipoproteins for increased blood stream transport.

Coenzyme A

Enzyme Reagent Coenzyme A (CoA, CoASH or HSCoA) is the key cofactor in first step of the TCA cycle, responsible for transferring the acetyl group from pyruvate oxidation to oxaloacetate yielding citrate. Available through Sigma-Aldrich online.

LOPAC^®1280 Small Molecules Screening

Explore compound library screening options with our Pharmacologically Active Compounds portfolio.

Decorin

Decorin's role in connective tissues underscores its importance in skeletal system extracellular matrix composition.

Dipeptidyl Peptidase IV

Native DPPIV, a type II transmembrane glycoprotein, functions as a serine protease in the S9 prolyl-oligopeptidase family.

Drug Conjugate Analysis using β-Glucuronidases

Drug conjugate analysis and the enzymatic hydrolysis of glucuronides

Enzyme Commission Numbers

Complete List of Enzyme Commission Numbers for metabolics research.

Enzymes for Alternative Energy

Explore the hurdles in unlocking glucose energy from lignocellulosic biomass, surpassing challenges compared to starch.

Fibrinogen/Fibrin

Fibrinogen, an acute phase glycoprotein, plays a vital role in the coagulation cascade of proteins.

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