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Claudia Eberle et al.
PloS one, 7(9), e45361-e45361 (2012-10-03)
Maternal immunization with oxidized lipoproteins prior to pregnancy protects against atherogenic in utero programming by gestational hypercholesterolemia and enhances beneficial lymphocyte-dependent immune responses in offspring. To determine whether in utero programming and immunomodulation also affect insulin resistance (IR) and type
Effects of A2BR on the biological behavior of mouse renal fibroblasts during hypoxia
Tang Jin, et al.
Molecular Medicine Reports, 11(6), 4397-4402 (2015)
Koen Kole et al.
GigaScience, 6(10), 1-6 (2017-10-13)
Experience-dependent plasticity (EDP) is essential for anatomical and functional maturation of sensory circuits during development. Although the principal synaptic and circuit mechanisms of EDP are increasingly well studied experimentally and computationally, its molecular mechanisms remain largely elusive. EDP can be
Karen K McKee et al.
The Journal of biological chemistry, 284(13), 8984-8994 (2009-02-05)
Laminins that possess three short arms contribute to basement membrane assembly by anchoring to cell surfaces, polymerizing, and binding to nidogen and collagen IV. Although laminins containing the alpha4 and alpha5 subunits are expressed in alpha2-deficient congenital muscular dystrophy, they
Fuqiang Chen et al.
Bio-protocol, 7(15), e2432-e2432 (2017-08-05)
Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) and CRISPR-associated (Cas) systems function as an adaptive immune system in bacteria and archaea for defense against invading viruses and plasmids (Barrangou and Marraffini, 2014). The effector nucleases from some class 2 CRISPR-Cas
Alex J McCarthy et al.
Infection and immunity, 87(5) (2019-03-06)
Gastrointestinal (GI) colonization of 2-day-old (P2) rat pups with Escherichia coli K1 results in translocation of the colonizing bacteria across the small intestine, bacteremia, and invasion of the meninges, with animals frequently succumbing to lethal infection. Infection, but not colonization
Jin Tang et al.
Molecular medicine reports, 11(6), 4397-4402 (2015-02-13)
Fibroblasts are the effector cells of collagen secretion in renal interstitial fibrosis (RIF), and their proliferation and activation are essential for the development of RIF. Hypoxic ischemia in local tissues has been identified in chronic kidney diseases (CKDs), with adenosine
Diego Ottaviani et al.
Genome research, 18(11), 1778-1786 (2008-10-14)
The folding of chromatin into topologically constrained loop domains is essential for genomic function. We have identified genomic anchors that define the organization of chromatin loop domains across the human major histocompatibility complex (MHC). This locus contains critical genes for
An efficient mannose selection protocol for tomato that has no adverse effect on the ploidy level of transgenic plants
Sigareva M, et al.
Plant Cell Reports, 23(4), 236-245 (2004)
Patrick Caspers et al.
Antimicrobial agents and chemotherapy, 53(9), 3620-3627 (2009-06-24)
Racemic 2,4-diaminopyrimidine dihydrophthalazine derivatives BAL0030543, BAL0030544, and BAL0030545 exhibited low in vitro MICs toward small, selected panels of Enterococcus faecalis, Enterococcus faecium, Streptococcus pneumoniae, Moraxella catarrhalis, and Mycobacterium avium, though the compounds were less active against Haemophilus influenzae. The constellation
S Kwok et al.
Nature, 339(6221), 237-238 (1989-05-18)
The exquisite sensitivity of the polymerase chain reaction means DNA contamination can ruin an entire experiment. Tidiness and adherence to a strict set of protocols can avoid disaster.
Bini Mathew et al.
European journal of medicinal chemistry, 210, 112952-112952 (2020-11-04)
ALS is a rare type of progressive neurological disease with unknown etiology. It results in the gradual degeneration and death of motor neurons responsible for controlling the voluntary muscles. Identification of mutations in the superoxide dismutase (SOD) 1 gene has
Jana Goldová et al.
BMC genomics, 12, 437-437 (2011-09-02)
The genome of Pseudomonas aeruginosa contains at least three genes encoding eukaryotic-type Ser/Thr protein kinases, one of which, ppkA, has been implicated in P. aeruginosa virulence. Together with the adjacent pppA phosphatase gene, they belong to the type VI secretion
Long-range jumping of incompletely extended polymerase chain fragments generates unexpected products.
L M Huang et al.
BioTechniques, 16(2), 242-244 (1994-02-01)
Madhavi A Naik et al.
International journal of surgical pathology, 28(4), 371-381 (2019-12-25)
Cystic neutrophilic granulomatous mastitis (CNGM) is a histologically characterized variant of granulomatous lobular mastitis that is associated with lipophilic Corynebacterium species. It remains a largely underrecognized entity in India. Our aim was to study CNGM in the Asian Indian population
'Touchdown' PCR to circumvent spurious priming during gene amplification.
R H Don et al.
Nucleic acids research, 19(14), 4008-4008 (1991-07-25)
Daniel Fil et al.
Neurobiology of disease, 177, 105996-105996 (2023-01-14)
Friedreich's ataxia (FRDA) is a neurodegenerative disease caused by reduced expression of the mitochondrial protein frataxin (FXN). Most FRDA patients are homozygous for large expansions of GAA repeats in intron 1 of FXN, while some are compound heterozygotes with an
Valerie F Boltz et al.
Retrovirology, 13(1), 87-87 (2016-12-22)
Although next generation sequencing (NGS) offers the potential for studying virus populations in unprecedented depth, PCR error, amplification bias and recombination during library construction have limited its use to population sequencing and measurements of unlinked allele frequencies. Here we report
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