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关键词:'S6324'
显示 1-11 共 11 条结果 关于 "S6324" 范围 论文
Ian J McGough et al.
Nature communications, 9(1), 3737-3737 (2018-09-15)
Wntless transports Wnt morphogens to the cell surface and is required for Wnt secretion and morphogenic gradients formation. Recycling of endocytosed Wntless requires the sorting nexin-3 (SNX3)-retromer-dependent endosome-to-Golgi transport pathway. Here we demonstrate the essential role of SNX3-retromer assembly for
Defining a holoprosencephaly locus on human chromosome 14q13 and characterization of potential candidate genes
Kamnasaran D, et al.
Genomics, 85(5), 608-621 (2005)
Sorting nexin 6 interacts with breast cancer metastasis suppressor-1 and promotes transcriptional repression
Rivera J, et al.
Journal of Cellular Biochemistry, 111(6), 1464-1472 (2010)
Proteomic identification of sorting nexin 6 as a negative regulator of BACE1-mediated APP processing
Okada H, et al.
Faseb Journal, 24(8), 2783-2794 (2010)
Sorting nexin 6 enhances lamin a synthesis and incorporation into the nuclear envelope
Gonzalez-Granado JM, et al.
PLoS ONE, 9(12) (2014)
Ana Jimenez-Orgaz et al.
The EMBO journal, 37(2), 235-254 (2017-11-22)
Retromer is an endosomal multi-protein complex that organizes the endocytic recycling of a vast range of integral membrane proteins. Here, we establish an additional retromer function in controlling the activity and localization of the late endosomal small GTPase RAB7. Surprisingly
Akshay Bareja et al.
The Journal of biological chemistry, 293(17), 6449-6459 (2018-03-14)
The insulin-like growth factor 1 receptor (IGF1R) is a receptor tyrosine kinase with critical roles in various biological processes. Recent results from clinical trials targeting IGF1R indicate that IGF1R signaling pathways are more complex than previously thought. Moreover, it has
Boris Simonetti et al.
The Journal of cell biology, 216(11), 3695-3712 (2017-09-25)
Endosomal recycling of transmembrane proteins requires sequence-dependent recognition of motifs present within their intracellular cytosolic domains. In this study, we have reexamined the role of retromer in the sequence-dependent endosome-to-trans-Golgi network (TGN) transport of the cation-independent mannose 6-phosphate receptor (CI-MPR).
Arunas Kvainickas et al.
The Journal of cell biology, 216(11), 3677-3693 (2017-09-25)
The retromer complex, which recycles the cation-independent mannose 6-phosphate receptor (CI-MPR) from endosomes to the trans-Golgi network (TGN), is thought to consist of a cargo-selective VPS26-VPS29-VPS35 trimer and a membrane-deforming subunit of sorting nexin (SNX)-Bin, Amphyphysin, and Rvs (BAR; SNX-BAR)
Florian Steinberg et al.
Nature cell biology, 15(5), 461-471 (2013-04-09)
The PDZ-domain-containing sorting nexin 27 (SNX27) promotes recycling of internalized transmembrane proteins from endosomes to the plasma membrane by linking PDZ-dependent cargo recognition to retromer-mediated transport. Here, we employed quantitative proteomics of the SNX27 interactome and quantification of the surface
The proximity-labeling technique BioID identifies sorting nexin 6 as a member of the insulin-like growth factor 1 (IGF1)-IGF1 receptor pathway
Bareja A, et al.
Test, 293(17), 6449-6459 (2018)
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