跳转至内容
Merck
CN
  • Comparison of the bioavailability and intestinal absorption sites of phytoene, phytofluene, lycopene and β-carotene.

Comparison of the bioavailability and intestinal absorption sites of phytoene, phytofluene, lycopene and β-carotene.

Food chemistry (2019-07-29)
Paula Mapelli-Brahm, Marielle Margier, Charles Desmarchelier, Charlotte Halimi, Marion Nowicki, Patrick Borel, Antonio J Meléndez-Martínez, Emmanuelle Reboul
摘要

The mechanisms of main tomato carotenes (phytoene, phytofluene, lycopene and β-carotene) intestinal absorption are still only partly understood. We thus compared carotene bioavailability in mice after gavage with carotene-rich oil-in-water emulsions. We also determined each carotene absorption profile along the duodenal-ileal axis of the intestine to identify their respective absorption sites and compared these profiles with the gene expression sites of their identified transporters, i.e. SR-BI and CD36. Our data show that phytofluene presented a significantly higher bioavailability compared to lycopene and β-carotene (areas under the curve of 0.76 ± 0.09 vs. 0.30 ± 0.05, 0.09 ± 0.05 and 0.08 ± 0.01 μmol/L·h for phytofluene, phytoene, lycopene and β-carotene, respectively). β-Carotene was mostly converted in the proximal and median intestine. Phytoene and phytofluene accumulation tended to be more important in the distal intestine, which did not correlate with the proximal expression of both Scarb1 and CD36. Overall, these results highlight the high bioavailability of phytofluene.

材料
Product Number
品牌
产品描述

Sigma-Aldrich
松果菊酮, ≥95.0% (HPLC)
登录查看公司和协议定价
货号包装规格是否有货价格数量
1 mg
请联系客服了解存货情况
新价格,新优惠!
CN¥8,248.46