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HomeGas Chromatography (GC) Selecting GC Columns by Industry or Application

Selecting GC Columns by Industry or Application

Gas chromatography, first established in the 1950′s, is a mature analytical technique with many established applications. Therefore, it is probable that documented methods or journal articles exist stating which stationary phases have successfully been used for a given application. Today, GC is the preferred chromatographic technique in the environmental, petroleum, chemical, flavor & fragrance, and forensic industries. In the biofuel, agriculture, food & beverage, cosmetic and personal care/cleaning product, and clinical industries, its frequency of use is equal to other chromatographic techniques. It is used for specific chromatographic applications in the industrial hygiene, pharmaceutical, and life science industries.

We have identified the GC columns that are routinely used in the various industries. These are conveniently arranged by industry, and then application within that industry, to simplify the process of selecting the proper phase.



Environmental Industry

The environmental columns offered here can be used with many specific methods for the analyses of volatiles, semivolatiles, pesticides, PCBs, herbicides, PAHs, and dioxins.

* Includes: organochlorine pesticides, PCBs as Aroclors, herbicides, organophosporus pesticides, nitrosamines, phenols, phthalate esters, haloacetic acids, disinfection by-products and solvents, and PAHs.

Industrial Hygiene

These columns can be used with methodologies designed to monitor workplace air quality.

  • For US EPA Method IP-8, choose SLB®-5ms
  • For NIOSH Method 1003, choose VOCOL®
  • For NIOSH Method 1403, choose Equity®-1
  • For NIOSH Method 1500/1501, choose Equity®-1
  • For NIOSH Method 2530, choose SLB®-5ms
  • For NIOSH Method 2542, choose Equity®-1
  • For NIOSH Method 5503, choose SLB®-5ms
  • For OSHA Method 52, choose SUPELCOWAX® 10
  • For OSHA Method 53, choose Equity®-1
  • For OSHA Method 56, choose Equity®-1
  • For OSHA Method 62, choose SLB®-5ms
  • For OSHA Method 80, choose SUPELCOWAX® 10

Petroleum Industry

This family of columns can be used for methods to measure purity, determine composition, and identify impurities in petroleum products.

Biofuels

These columns can be used to measure purity and to monitor for impurities in biofuels.

  • For bioethanol (ethanol content), choose Petrocol® DH 150
  • For biodiesel (FAME profile), choose Omegawax®, SLB®-IL60i, and SLB®-IL111i
  • For biodiesel (glycerin impurity), choose MET-Biodiesel and SPB®-Biodiesel
  • For biodiesel (methanol impurity), choose Equity®-1

Chemical Industry

These special purpose columns can be selected for analyses such as solvents, aromatics, light hydrocarbons, fluorocarbons, sulfur-containing compounds, glycols, basic compounds, and much more.

  • For solvents, choose SLB®-5ms, SUPELCOWAX® 10, and SLB®-IL60i
  • For C1-C5 alkanes, alkenes, and alkynes, choose Alumina sulfate PLOT, Alumina KCl PLOT, and Silica PLOT
  • For impurities in ethylene, choose Alumina sulfate PLOT
  • For impurities in propylene, choose Alumina sulfate PLOT
  • For aromatics, choose SUPELCOWAX® 10, SLB®-IL59, SLB®-IL60i, SLB®-IL111i, SLB®-ILD3606, and Bentone 34/DNDP SCOT
  • For impurities in toluene, choose TCEP, SLB®-IL100, and TCEP SCOT
  • For xylene isomers, choose SUPELCOWAX® 10, SLB®-IL59, SLB®-IL60i, and Bentone 34/DNDP SCOT
  • For mineral spirits, choose TCEP and TCEP SCOT
  • For chlorinated solvents, choose SLB®-5ms, SUPELCOWAX® 10, and SLB®-IL60i
  • For pesticides, choose SLB®-5ms and chiral
  • For fluorocarbons, choose Supel-Q™ PLOT, Alumina KCl PLOT, and Silica PLOT
  • For alcohols, choose Equity®-1, SLB®-5ms, SUPELCOWAX® 10, SLB®-IL60i, and chiral
  • For glycol ethers (cellosolves), diols, and glycols, choose SPB®-1000, Nukol™, SLB®-IL60i, and chiral
  • For formalin, choose Carboxen® 1006 PLOT
  • For ketones, choose Equity®-1, SLB®-5ms, SUPELCOWAX® 10, SLB®-IL60i, and chiral
  • For carboxylic acids as methyl esters, choose SP®-2380, SLB®-IL111i, and chiral
  • For dicarboxylic acids as dimethyl esters, choose SP®-2380 and SLB®-IL111i
  • For tall oil fatty acid as methyl esters, choose SP®-2380 and SLB®-IL111i
  • For esters and ethers, choose SPB®-1000, Nukol™, SLB®-IL60i, and chiral
  • For impurities in MTBE, choose Petrocol® DH Octyl, Petrocol® DH 50.2, Petrocol® DH, and Petrocol® DH 150
  • For terpenes, choose Equity®-1, SLB®-5ms, SLB®-IL59, SLB®-IL60i, SLB®-IL111i, and chiral
  • For amines, choose PTA-5, Carbowax® Amine, SLB®-IL59, and SLB®-IL60i
  • For aromatic amines (anilines), choose PTA-5, Carbowax® Amine, SLB®-IL59, and SLB®-IL60i
  • For sulfur compounds, choose SPB®-1 SULFUR, SLB®-IL59, SLB®-IL60i, Supel-Q™ PLOT, and Silica PLOT
  • For dissolved gas analysis (DGA), choose Carboxen® 1010 PLOT
  • For gases and light hydrocarbons, choose Carboxen® 1010 PLOT, Carboxen® 1006 PLOT, Supel-Q™ PLOT, Alumina sulfate PLOT, Alumina KCl PLOT, Silica PLOT, and Mol Sieve 5A PLOT
  • For process analyzers, choose Bentone 34/DNDP SCOT, TCEP SCOT, BMEA SCOT, and Squalane SCOT

Agricultural Industry

These columns are suitable for purity and contaminant detection applications performed by grain growers, edible oil producers, and agrochemical manufacturers.

  • For edible oils, choose SLB®-5ms, SAC™-5, Omegawax®, SLB®-IL59, SLB®-IL60i, SP®-2380, SP®-2560, and SLB®-IL111i
  • For free fatty acids, choose Nukol™ and SPB®-1000
  • For FAMEs by boiling point elution, choose Equity®-1
  • For FAMEs by degree of unsaturation, choose SPB®-PUFA, Omegawax®, SLB®-IL59, and SLB®-IL60i
  • For omega 3 and omega 6 FAMEs, choose SPB®-PUFA, Omegawax®, SLB®-IL59, and SLB®-IL60i
  • For cis/trans FAME isomers, choose SP®-2380, SP®-2560, and SLB®-IL111i
  • For mono-, di-, and triglycerides, choose MET-Biodiesel and SLB®-35ms
  • For pesticides, choose SLB®-5ms, SLB®-35ms, Equity®-1701, SPB®-608, and chiral
  • For dioxins, choose SLB®-5ms, SPB®-225, and SP®-2331
  • For flavors, fragrances, and aroma, choose Equity®-1, SLB®-5ms, SUPELCOWAX® 10, SLB®-IL60i, and chiral

Food and Beverage Industry

These columns are suitable for food composition/nutrition applications, as well as for food safety applications.

  • For sugars as alditol acetates, choose SPB®-624 and Equity®-1701
  • For free fatty acids, choose Nukol™ and SPB®-1000
  • For FAMEs by boiling point elution, choose Equity®-1
  • For FAMEs by degree of unsaturation, choose SPB®-PUFA, Omegawax®, SLB®-IL59, and SLB®-IL60i
  • For omega 3 and omega 6 FAMEs, choose SPB®-PUFA, Omegawax®, SLB®-IL59, and SLB®-IL60i
  • For cis/trans FAME isomers, choose SP®-2380, SP®-2560, and SLB®-IL111i
  • For fatty acid ethyl esters (FAEEs), choose SLB®-5ms, Omegawax®, SLB®-IL59, SLB®-IL60i, SP®-2380, SP®-2560, and SLB®-IL111i
  • For mono-, di-, and triglycerides, choose MET-Biodiesel and SLB®-35ms
  • For sterols, aliphatic alcohols, and waxes, choose MET-Biodiesel and SAC™-5
  • For amino acids, choose SLB®-5ms and chiral
  • For nutraceuticals and antioxidants, choose SLB®-5ms
  • For organic acids, choose SLB®-5ms, Nukol™, SPB®-1000, SUPELCOWAX® 10, and SLB®-IL60i
  • For flavors, fragrances, and aroma, choose Equity®-1, SLB®-5ms, SLB®-35ms, SUPELCOWAX® 10, SLB®-IL60i, and chiral
  • For preservatives, choose SLB®-5ms
  • For pesticide residues, choose SLB®-5ms, SLB®-35ms, Equity®-1701, SPB®-608, and chiral
  • For veterinary drug residues, choose SLB®-5ms, SLB®-35ms,Equity®-1701, and SPB®-608
  • For allergens, choose SLB®-5ms
  • For dioxins, furans, and PCBs, choose SPB®-Octyl, SLB®-5ms, SPB®-225, and SP®-2331
  • For phthalate esters, choose SLB®-5ms and SLB®-35ms
  • For bisphenol A, BADGE, BFDGE, and NOGE, choose SLB®-5ms
  • For benzene, choose SPB®-624, VOCOL®, SLB®-IL59, SLB®-IL60i, and SLB®-IL111i
  • For nitrosamines, choose SLB®-5ms, SLB®-35ms,SLB®-IL59, and SLB®-IL60i
  • For furans, choose Carboxen® 1010 PLOT, Carboxen® 1006 PLOT, Supel-Q™ PLOT, Alumina sulfate PLOT, Alumina chloride PLOT, and Mol Sieve 5A PLOT
  • For PAHs, choose SLB®-ILPAH or SLB®-PAHms
  • For acrylamide, choose SUPELCOWAX® 10
  • For 3-MCPD, choose SLB®-5ms
  • For disinfection by-products and solvents, choose SLB®-5ms, SLB®-35ms, and Equity®-1701
  • For adulterants, choose SLB®-5ms and SUPELCOWAX® 10
  • For beverage analysis, choose SLB®-5ms, SLB®-35ms, SPB®-20, Equity®-1701, SPB®-35, SPB®-50, Nukol™, SPB®-1000, SUPELCOWAX® 10, SLB®-IL60i, and Supel-Q™ PLOT
  • For sulfur compounds in beverages, choose SPB®-1 SULFUR, SLB®-IL59, SLB®-IL60i, and Supel-Q™ PLOT

Flavor and Fragrance Industry

Volatiles, essential oils, and small chiral molecules of interest to this industry can be analyzed using the following columns.

  • For volatiles, choose Equity®-1, SLB®-5ms, SLB®-35ms, SUPELCOWAX® 10, SLB®-IL60i, and chiral
  • For essential oils, choose Equity®-1, SLB®-5ms, SLB®-35ms, SUPELCOWAX® 10, SLB®-IL60i, and chiral

Cosmetics/Cleaning Products

Commercial products, such as shampoos, cosmetics, and rug cleaners, are tested to confirm correct composition, and to ensure that they do not contain items hazardous to the user. These columns can be used for this purpose.

  • For alkalis, choose PTA-5 and Carbowax® Amine
  • For allergens, choose SLB®-5ms
  • For coloring compounds, choose SLB®-5ms, SLB®-35ms, SPB®-1000, Nukol™, and SUPELCOWAX® 10
  • For fragrance compounds, choose Equity®-1, SLB®-5ms, SLB®-35ms, SUPELCOWAX® 10, SLB®-IL60i, and chiral
  • For glycols, choose SPB®-1000, Nukol™, and SLB®-IL60i
  • For preservatives, choose SLB®-5ms
  • For solvents in cleaning products, choose SLB®-5ms, SLB®-35ms, SPB®-1000, Nukol™, and SUPELCOWAX® 10
  • For surfactants: anionic, choose SPB®-1000 and Nukol™
  • For surfactants: nonionic, choose Equity®-1 and SLB®-5ms

Pharma Industry (biopharma and small molecule pharmaceuticals)

Use these columns for analyses of residual solvents, basic drugs, small chiral molecules of interest to this industry, and for methods following specific monographs.

  • For residual solvents, choose Equity®-5, OVI-G43, and SUPELCOWAX® 10
  • For active pharmaceutical ingredients (APIs), choose SLB®-5ms, PTA-5, Carbowax® Amine, and chiral
  • For preservatives, choose SLB®-5ms
  • For heptafluoropropanes, choose Alumina chloride PLOT

Clinical Industry

Use these columns for the analyses of analytes from biological fluids.

  • For antidepressants, choose Equity®-1701
  • For antiepileptics, choose SPB®-20 and Equity®-1701
  • For antihistamines, choose PTA-5, Carbowax® Amine, SLB®-IL59, and SLB®-IL60i
  • For bacterial acid methyl esters (BAMEs), choose SLB®-5ms, Omegawax®, SLB®-IL59, SLB®-IL60i, SP®-2380, SP®-2560, and SLB®-IL111i
  • For basic drug screen, choose SLB®-5ms, PTA-5, SLB®-35ms, SPB®-35, Carbowax® Amine, SLB®-IL59, and SLB®-IL60i
  • For benzodiazepines as acetic anhydride derivatives, choose Equity®-1
  • For benzodiazepines as TBDMS derivatives, choose SLB®-35ms, SPB®-35, SLB®-IL59, and SLB®-IL60ii
  • For carboxylic acids as methyl esters, choose SP®-2380, SP®-2560, SLB®-IL111i, and chiral
  • For cold and sinus medications, choose PTA-5, Carbowax® Amine, SLB®-IL59, and SLB®-IL60i
  • For Deprenyl (Selegiline), choose chiral
  • For estrogens, choose SLB®-5ms
  • For free fatty acids, choose Nukol™ and SPB®-1000
  • For FAMEs by boiling point elution, choose Equity®-1
  • For FAMEs by degree of unsaturation, choose SPB®-PUFA, Omegawax®, SLB®-IL59, and SLB®-IL60i
  • For omega 3 and omega 6 FAMEs, choose SPB®-PUFA, Omegawax®, SLB®-IL59, and SLB®-IL60i
  • For cis/trans FAME isomers, choose SP®-2380, SP®-2560, and SLB®-IL111i
  • For mono-, di-, and triglycerides, choose MET-Biodiesel and SLB®-35ms
  • For NSAIDs, choose chiral
  • For phenothiazines, choose SLB®-5ms
  • For psychostimulants, choose chiral
  • For steroids, choose Equity®-1, SLB®-5ms, and SAC™-5
  • For sympathomimetic amines, choose PTA-5, Carbowax® Amine, and SLB®-IL59
  • For sympathomimetic amines as HFBA derivatives, choose SLB®-5ms
  • For sympathomimetic amines as TFAA derivatives, choose SLB®-5ms

Forensics Industry

Use these columns for the analyses of accelerants from arson samples, or for blood alcohols and drugs of abuse from biological fluids.

  • For accelerants, choose Equity®-1 and SLB®-5ms
  • For blood alcohols, choose Equity®-1 and VOCOL®
  • For explosives, use SLB®-5ms
  • For glycols, choose SPB®-1000 and Nukol™
  • For drugs of abuse: drug screen as TBDMS derivatives, choose SLB®-5ms, SLB®-35ms, and SPB®-35
  • For drugs of abuse: drug screen as TMS derivatives, choose SLB®-5ms, SLB®-35ms, and SPB®-35
  • For drugs of abuse: basic drug screen, choose SLB®-5ms, PTA-5, SLB®-35ms, SPB®-35, Carbowax® Amine, and SLB®-IL59
  • For drugs of abuse: amphetamines, choose SLB®-5ms, SLB®-35ms, SPB®-35, and chiral
  • For drugs of abuse: antidepressants, choose Equity®-1701
  • For drugs of abuse: barbiturates, choose SLB®-5ms, Equity®-1701, SLB®-35ms, and SPB®-35
  • For drugs of abuse: cannabis, choose Equity®-1
  • For drugs of abuse: cannabinoids as TMS derivatives, choose SLB®-5ms, SLB®-35ms, and SPB®-35
  • For drugs of abuse: cocaine as TMS derivatives, choose SLB®-5ms, SLB®-35ms, and SPB®-35
  • For drugs of abuse: GHB as MTBSTFA derivatives, choose SLB®-5ms
  • For drugs of abuse: inhalants, choose Equity®-5 and VOCOL®
  • For drugs of abuse: ketamines as MBTFA derivatives, choose SLB®-5ms
  • For drugs of abuse: LSD as TMS derivatives, choose SLB®-5ms. SLB®-35ms, and SPB®-35
  • For drugs of abuse: MDMA (Ecstasy) as HFBPC derivatives, choose SLB®-5ms
  • For drugs of abuse: opiates as TMS derivatives, choose SLB®-5ms, SLB®-35ms, and SPB®-35
  • For drugs of abuse: phencyclidine (PCP), choose SLB®-5ms
  • For drugs of abuse: psychostimulants, choose chiral
  • For drugs of abuse: steroids, choose SAC™-5 and Equity®-5
  • For drugs of abuse: tryptamines, choose SLB®-5ms

Life Science Industry

Proteins, peptides, and amino acids are of importance to the life science industry.

  • For amino acids, choose SLB®-5ms and chiral
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