Merck
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CDK1

cyclin-dependent kinase 1

别名:
CDC2, CDC28A, P34CDC2
物种:
UniProtKB ID:
基因ID:
  • Human(983) Summary: The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF), which is essential for G1/S and G2/M phase transitions of eukaryotic cell cycle. Mitotic cyclins stably associate with this protein and function as regulatory subunits. The kinase activity of this protein is controlled by cyclin accumulation and destruction through the cell cycle. The phosphorylation and dephosphorylation of this protein also play important regulatory roles in cell cycle control. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
  • Mouse(12534) cyclin-dependent kinase 1
  • Rat(54237) cyclin-dependent kinase 1
  • dog(488997) cyclin-dependent kinase 1
  • Zebrafish(80973) cyclin-dependent kinase 1
  • chicken(396252) cyclin-dependent kinase 1
  • naked mole-rat(101717463) cyclin-dependent kinase 1
  • domestic guinea pig(100735946) cyclin-dependent kinase 1
  • Goat(100861361) cyclin-dependent kinase 1
  • cow(281061) cyclin-dependent kinase 1
  • sheep(100216432) cyclin-dependent kinase 1

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Antibodies

货号
说明
物种反应性
应用
Anti-Phospho-CDK1-T14 antibody produced in rabbit, ,
物种反应性
human, mouse, rat
应用
immunofluorescence
western blot
Anti-CDK1 antibody produced in rabbit, ,
物种反应性
human, mouse, rat
应用
immunohistochemistry
western blot
Rabbit anti-CDK1 Antibody, Affinity Purified, Powered by Bethyl Laboratories, Inc.,
物种反应性
human
应用
immunoprecipitation (IP)
western blot
Anti-Phospho-CDK1-T161 antibody produced in rabbit, ,
物种反应性
human, mouse
应用
immunofluorescence
immunohistochemistry

immunoprecipitation (IP)

western blot
Anti-CDK1 antibody produced in rabbit, ,
物种反应性
human, mouse, rat
应用
immunofluorescence
immunohistochemistry

western blot

Small Molecule - Inhibitor

货号
说明
物种
R547, ≥98% (HPLC),
物种
human
核抑制剂, ≥98% (TLC),
物种
human, mouse, rat

Proteins

货号
说明
物种
CDK1/CyclinA1, active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
物种
human
CDK1/CyclinB1, active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
物种
human
CDK1/细胞周期蛋白 A2,活性,GST 标记 人, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
物种
human

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting human CDK1,
物种
human