Merck
CN

CHRM4

cholinergic receptor, muscarinic 4

别名:
HM4, M4R
物种:
UniProtKB ID:
基因ID:
  • Human(1132) Summary: The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The clinical implications of this receptor are unknown; however, mouse studies link its function to adenylyl cyclase inhibition. [provided by RefSeq, Jul 2008]
  • Mouse(12672) cholinergic receptor, muscarinic 4
  • Rat(25111) cholinergic receptor, muscarinic 4
  • domestic guinea pig(100714736) cholinergic receptor, muscarinic 4
  • naked mole-rat(101726411) cholinergic receptor, muscarinic 4
  • Domestic Rabbit(100008791) cholinergic receptor, muscarinic 4
  • dog(611314) cholinergic receptor, muscarinic 4
  • cow(512928) cholinergic receptor, muscarinic 4
  • sheep(101114554) cholinergic receptor, muscarinic 4
  • domestic cat(101088360) cholinergic receptor, muscarinic 4
  • chicken(423195) cholinergic receptor, muscarinic 4

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Small Molecule - Agonist

货号
说明
物种
乙酰基-β-氯化甲基胆碱, ≥98% (TLC), powder,
物种
human
氧化震颤素M, solid,
物种
human
卡巴胆碱, ≥98% (titration), crystalline,
物种
human, mouse, rat

Small Molecule - Antagonist

货号
说明
物种
比沙可啶, analytical standard, for drug analysis,
物种
human
托吡卡胺, solid,
物种
human
溴丙胺太林, ≥97% (TLC), powder,
物种
human
Dicyclomine hydrochloride, ≥99% (TLC), powder,
物种
human
盐酸奥昔布宁, ≥98% (TLC), powder,
物种
human

Antibodies

货号
说明
物种反应性
应用
Anti-CHRM4 Antibody, clone 18C7.2 ZooMAb® Mouse Monoclonal, recombinant, expressed in HEK 293 cells,
物种反应性
human
应用
ELISA
affinity binding assay

immunocytochemistry

western blot
Anti-CHRM4 antibody produced in rabbit, affinity isolated antibody,
物种反应性
human, mouse, rat
应用
western blot
Anti-Muscarinic Acetylcholine Receptor m4 Antibody, clone 18C7.2, clone 18C7.2, Chemicon®, from mouse,
物种反应性
monkey
应用
immunohistochemistry
immunoprecipitation (IP)

western blot
Anti-Muscarinic Acetylcholine Receptor m4 Antibody, clone 17F10.2, purified antibody, clone 17F10.2, Chemicon®,
物种反应性
monkey, mouse, rat
应用
immunocytochemistry
immunoprecipitation (IP)

western blot

Small Molecule - Inhibitor

货号
说明
物种
盐酸阿米替林 盐酸盐, ≥98% (TLC), powder,
物种
human

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting mouse Chrm4,
物种
mouse