Merck
CN

CNR1

cannabinoid receptor 1 (brain)

别名:
CANN6, CB-R, CB1, CB1A, CB1K5, CB1R, CNR
物种:
UniProtKB ID:
基因ID:
  • Human(1268) Summary: This gene encodes one of two cannabinoid receptors. The cannabinoids, principally delta-9-tetrahydrocannabinol and synthetic analogs, are psychoactive ingredients of marijuana. The cannabinoid receptors are members of the guanine-nucleotide-binding protein (G-protein) coupled receptor family, which inhibit adenylate cyclase activity in a dose-dependent, stereoselective and pertussis toxin-sensitive manner. The two receptors have been found to be involved in the cannabinoid-induced CNS effects (including alterations in mood and cognition) experienced by users of marijuana. Multiple transcript variants encoding two different protein isoforms have been described for this gene. [provided by RefSeq, May 2009]
  • Mouse(12801) cannabinoid receptor 1 (brain)
  • Rat(25248) cannabinoid receptor 1 (brain)
  • Zebrafish(404209) cannabinoid receptor 1
  • Horse(100065681) cannabinoid receptor 1 (brain)
  • naked mole-rat(101697935) cannabinoid receptor 1 (brain)
  • domestic guinea pig(100169690) cannabinoid receptor 1 (brain)
  • cow(100299449) cannabinoid receptor 1 (brain)
  • sheep(101111639) cannabinoid receptor 1 (brain)
  • domestic cat(493926) cannabinoid receptor 1 (brain)
  • dog(481913) cannabinoid receptor 1 (brain)
  • chicken(428633) cannabinoid receptor 1 (brain)

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Small Molecule - Agonist

货号
说明
物种
花生四烯酸乙醇胺, ≥97.0% (TLC), oil,
物种
rat
( R )-(+)-WIN 55,212-2 甲磺酸盐, ≥98% (HPLC),
物种
human
花生四烯酸-2′-氯乙酰胺 水合物, ≥97% (HPLC), oil,
物种
rat, mouse
油酰单乙醇胺, ~98% (TLC),
物种
human, mouse, rat

Small Molecule - Antagonist

货号
说明
物种
硬脂酰乙醇酰胺, ≥98%, crystalline,
物种
rat
AM281, ≥98% (HPLC),
物种
rat
AM251, >98% (HPLC), solid,
物种
mouse, rat
棕榈酸异丙酯, technical grade, 90%,
物种
human, rat
棕榈酸异丙酯, ≥90%,
物种
human, rat

Antibodies

货号
说明
物种反应性
应用
Anti-Cannabinoid Receptor 1 Antibody, CT, Chemicon®, from rabbit,
物种反应性
mouse, rat
应用
ELISA
western blot
Monoclonal Anti-CNR1 antibody produced in mouse, clone 2F9, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
ELISA
western blot
Anti-CNR1 (N-terminal) antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
物种反应性
human, mouse
应用
ELISA
western blot
Anti-CNR1 antibody produced in rabbit, affinity isolated antibody,
物种反应性
human, mouse, rat
应用
ELISA
immunofluorescence

immunohistochemistry

western blot
Anti-Cannabinoid Receptor 1 Antibody, Chemicon®, from rabbit,
物种反应性
human, monkey, rat
应用
immunocytochemistry
immunohistochemistry

Small Molecule - Mixed Agonist/Antagonist

货号
说明
物种
棕榈酰, ,
物种
human, rat
CP-55940, >98% (HPLC), powder,
物种
human, rat

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting human CNR1,
物种
human
MISSION® esiRNA, targeting mouse Cnr1,
物种
mouse