Merck
CN

COL1A2

collagen, type I, alpha 2

别名:
OI4
物种:
UniProtKB ID:
基因ID:
  • Human(1278) Summary: This gene encodes the pro-alpha2 chain of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIB, recessive Ehlers-Danlos syndrome Classical type, idiopathic osteoporosis, and atypical Marfan syndrome. Symptoms associated with mutations in this gene, however, tend to be less severe than mutations in the gene for the alpha1 chain of type I collagen (COL1A1) reflecting the different role of alpha2 chains in matrix integrity. Three transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene. [provided by R. Dalgleish, Feb 2008]
  • Mouse(12843) collagen, type I, alpha 2
  • Rat(84352) collagen, type I, alpha 2
  • chicken(396243) collagen, type I, alpha 2
  • domestic guinea pig(100719158) collagen, type I, alpha 2
  • domestic cat(101089428) collagen, type I, alpha 2
  • Horse(100051715) collagen, type I, alpha 2
  • Zebrafish(336471) collagen, type I, alpha 2
  • Domestic Rabbit(100008997) collagen, type I, alpha 2
  • dog(403824) collagen, type I, alpha 2
  • naked mole-rat(101722393) collagen, type I, alpha 2
  • cow(282188) collagen, type I, alpha 2

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Antibodies

货号
说明
物种反应性
应用
抗I型胶原蛋白抗体 兔抗, affinity isolated antibody,
物种反应性
human, mouse, rat
应用
ELISA
immunofluorescence

immunohistochemistry
Anti-Collagen I α2 antibody produced in rabbit, affinity isolated antibody,
物种反应性
human
应用
ELISA
immunofluorescence

immunohistochemistry

western blot
Anti-COL1A2 antibody produced in rabbit, ,
物种反应性
mouse, rat
应用
immunohistochemistry
western blot
Anti-COL1A2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
物种反应性
human
应用
immunofluorescence

Proteins

货号
说明
物种
胶原 人, Bornstein and Traub Type I, acid soluble, powder, ~95% (SDS-PAGE),
物种
human

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting human COL1A2,
物种
human