CN
CAMK2A
calcium/calmodulin-dependent protein kinase II alpha
别名:
CAMKA
物种:
Human CAMK2A (815), Mouse Camk2a (12322), Rat Camk2a (25400), Zebrafish camk2a (550436), Domestic Rabbit CAMK2A (100341507), dog CAMK2A (612941), domestic cat CAMK2A (101084342), cow CAMK2A (530719), naked mole-rat Camk2a (101722229), domestic guinea pig Camk2a (100727059) ...展开
UniProtKB ID:
基因ID:
- Human(815) Summary: The product of this gene belongs to the serine/threonine protein kinases family, and to the Ca(2+)/calmodulin-dependent protein kinases subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. This calcium calmodulin-dependent protein kinase is composed of four different chains: alpha, beta, gamma, and delta. The alpha chain encoded by this gene is required for hippocampal long-term potentiation (LTP) and spatial learning. In addition to its calcium-calmodulin (CaM)-dependent activity, this protein can undergo autophosphorylation, resulting in CaM-independent activity. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Nov 2008]
- Mouse(12322) calcium/calmodulin-dependent protein kinase II alpha
- Rat(25400) calcium/calmodulin-dependent protein kinase II alpha
- Zebrafish(550436) calcium/calmodulin-dependent protein kinase (CaM kinase) II alpha
- Domestic Rabbit(100341507) calcium/calmodulin-dependent protein kinase II alpha
- dog(612941) calcium/calmodulin-dependent protein kinase II alpha
- domestic cat(101084342) calcium/calmodulin-dependent protein kinase II alpha
- cow(530719) calcium/calmodulin-dependent protein kinase II alpha
- naked mole-rat(101722229) calcium/calmodulin-dependent protein kinase II alpha
- domestic guinea pig(100727059) calcium/calmodulin-dependent protein kinase II alpha
- Horse(100071654) calcium/calmodulin-dependent protein kinase II alpha
- chicken(374175) calcium/calmodulin-dependent protein kinase II alpha
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Small Molecule - Antagonist
货号
说明
物种
Antibodies
货号
说明
物种反应性
应用
抗-CAMK2 兔抗, affinity isolated antibody,
物种反应性
human, mouse, rat
应用
ELISA
immunofluorescence
immunohistochemistry
western blot
immunofluorescence
immunohistochemistry
western blot
Monoclonal Anti-CaM Kinase IIα (CaMKIIα) antibody produced in mouse, clone 6G9, purified immunoglobulin, buffered aqueous solution,
物种反应性
mouse, rat
应用
immunofluorescence
western blot
western blot
抗-CaM激酶II抗体，α 亚基，克隆6G9, clone 6G9, Upstate®, from mouse,
物种反应性
bovine, rat
应用
immunohistochemistry
western blot
western blot
Monoclonal Anti-CAMK2A antibody produced in mouse, clone 2C4, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
ELISA
immunofluorescence
western blot
immunofluorescence
western blot
Anti-phospho-CaM Kinase II Antibody, α subunit, (Thr286), clone 22B1, clone 22B1, Upstate®, from mouse,
物种反应性
rat
应用
western blot
Small Molecule - Inhibitor
Proteins
esiRNA
Small Molecule - Substrate
货号
说明
物种