Merck
CN

CNR2

cannabinoid receptor 2 (macrophage)

别名:
CB-2, CB2, CX5
物种:
Human CNR2 (1269), Mouse Cnr2 (12802), Rat Cnr2 (57302), chicken CNR2 (428232), Horse CNR2 (100071536), domestic cat CNR2 (101100234), dog CNR2 (612289), cow CNR2 (539769), sheep CNR2 (101119188), domestic guinea pig Cnr2 (100721528)
UniProtKB ID:
P34972, Q4VBK8, Q5JRH7, Q6B0G7, Q6NSY0
基因ID:
  • Human(1269) Summary: The cannabinoid delta-9-tetrahydrocannabinol is the principal psychoactive ingredient of marijuana. The proteins encoded by this gene and the cannabinoid receptor 1 (brain) (CNR1) gene have the characteristics of a guanine nucleotide-binding protein (G-protein)-coupled receptor for cannabinoids. They inhibit adenylate cyclase activity in a dose-dependent, stereoselective, and pertussis toxin-sensitive manner. These proteins have been found to be involved in the cannabinoid-induced CNS effects (including alterations in mood and cognition) experienced by users of marijuana. The cannabinoid receptors are members of family 1 of the G-protein-coupled receptors. [provided by RefSeq, Jul 2008]
  • Mouse(12802) cannabinoid receptor 2 (macrophage)
  • Rat(57302) cannabinoid receptor 2 (macrophage)
  • chicken(428232) cannabinoid receptor 2 (macrophage)
  • Horse(100071536) cannabinoid receptor 2 (macrophage)
  • domestic cat(101100234) cannabinoid receptor 2 (macrophage)
  • dog(612289) cannabinoid receptor 2 (macrophage)
  • cow(539769) cannabinoid receptor 2 (macrophage)
  • sheep(101119188) cannabinoid receptor 2 (macrophage)
  • domestic guinea pig(100721528) cannabinoid receptor 2 (macrophage)
  • Zebrafish(795246) cannabinoid receptor 2

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Small Molecule - Agonist

货号
说明
物种
W102
( R )-(+)-WIN 55,212-2 甲磺酸盐, ≥98% (HPLC),
物种
human
A9719
花生四烯酸-2′-氯乙酰胺 水合物, ≥97% (HPLC), oil,
物种
rat, mouse
O0383
油酰单乙醇胺, ~98% (TLC),
物种
human, mouse, rat

Small Molecule - Antagonist

货号
说明
物种
A6226
AM251, >98% (HPLC), solid,
物种
mouse, rat
291781
棕榈酸异丙酯, technical grade, 90%,
物种
human, rat
W515604
棕榈酸异丙酯, ≥90%,
物种
human, rat
A9719
花生四烯酸-2′-氯乙酰胺 水合物, ≥97% (HPLC), oil,
物种
rat, mouse
P5177
棕榈酸甲酯, ≥99% (capillary GC),
物种
human, rat

Antibodies

货号
说明
物种反应性
应用
SAB4500346
Anti-CNR2 antibody produced in rabbit, affinity isolated antibody,
物种反应性
human
应用
ELISA
western blot
WH0001269M1
Monoclonal Anti-CNR2 antibody produced in mouse, clone 3C7, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
ELISA
immunofluorescence
western blot
C1358
Anti-Cannabinoid Receptor 2 antibody produced in rabbit, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human, rat
应用
immunocytochemistry
western blot

Small Molecule - Mixed Agonist/Antagonist

货号
说明
物种
P0359
棕榈酰, ,
物种
human, rat
C1112
CP-55940, >98% (HPLC), powder,
物种
human, rat

esiRNA

货号
说明
物种
EHU120781
MISSION® esiRNA, targeting human CNR2,
物种
human