CN

DRD4

dopamine receptor D4

别名:

D4DR

物种:

Human DRD4 (1815), Mouse Drd4 (13491), Rat Drd4 (25432), naked mole-rat Drd4 (101708437), dog DRD4 (448805), domestic guinea pig Drd4 (100733356), dog DRD4 (607223), chicken DRD4 (423016)

UniProtKB ID:

P21917, B0M0J7, Q7Z7Q5, Q8NGM5

基因ID:

Human(1815) Summary: This gene encodes the D4 subtype of the dopamine receptor. The D4 subtype is a G-protein coupled receptor which inhibits adenylyl cyclase. It is a target for drugs which treat schizophrenia and Parkinson disease. Mutations in this gene have been associated with various behavioral phenotypes, including autonomic nervous system dysfunction, attention deficit/hyperactivity disorder, and the personality trait of novelty seeking. This gene contains a polymorphic number (2-10 copies) of tandem 48 nt repeats; the sequence shown contains four repeats. [provided by RefSeq, Jul 2008]
Mouse(13491) dopamine receptor D4
Rat(25432) dopamine receptor D4
naked mole-rat(101708437) dopamine receptor D4
dog(448805) dopamine receptor D4
domestic guinea pig(100733356) dopamine receptor D4
dog(607223) dopamine receptor D4
chicken(423016) dopamine receptor D4

产品 (81)
同行评审论文 (518)

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Small Molecule - Agonist

货号

说明

物种

P233

PD 168,077 maleate salt, powder,

物种

human

普拉克索二盐酸盐, >98% (HPLC), powder,

物种

human

盐酸罗匹尼罗, Pharmaceutical Secondary Standard; Certified Reference Material,

物种

human

罗匹尼罗盐酸盐, European Pharmacopoeia (EP) Reference Standard,

物种

human

罗匹尼罗盐酸盐, United States Pharmacopeia (USP) Reference Standard,

物种

human

Small Molecule - Antagonist

货号

说明

物种

L131

L-745,870 hydrochloride, ,

物种

human

U115

U-101958 maleate salt, solid,

物种

human

L135

L-741,626, ≥98% (HPLC),

物种

human

氯丙嗪盐酸盐, VETRANAL^®, analytical standard,

物种

human

氯丙嗪盐酸盐, meets USP testing specifications,

物种

human

Antibodies

货号

说明

物种反应性

应用

Anti-Dopamine D4 Receptor Antibody, extracellular domain, Chemicon^®, from rabbit,

物种反应性

mouse

应用

ELISA
western blot

Anti-DRD4 Antibody, clone 2B9, clone 2B9, from mouse,

物种反应性

human, mouse, rat

应用

immunocytochemistry
western blot

Anti-Dopamine D₄ Receptor Rabbit pAb, lyophilized, Calbiochem^®,

物种反应性

human, rat

应用

Small Molecule - Inhibitor

货号

说明

物种

D052

GBR 12909 二盐酸盐, solid, ≥98% (HPLC),

物种

human

Amoxapine, 1.0 mg/mL in methanol, certified reference material, Cerilliant^®,

物种

human

阿莫沙平, Pharmaceutical Secondary Standard; Certified Reference Material,

物种

human

Amoxapine, United States Pharmacopeia (USP) Reference Standard,

物种

human

A129

Amoxapine, ,

物种

human

Small Molecule - Metabolite

货号

说明

物种

3-羟基-4-甲氧基苯乙胺盐酸盐, ,

物种

human

3-甲氧基酪胺盐酸盐, ≥95.5%, crystalline,

物种

human

Small Molecule - Mixed Agonist/Antagonist

货号

说明

物种

BP897, >98% (HPLC), solid,

物种

human, rat

氟哌啶醇, powder,

物种

human, rat

氯氮平标准液, ,

物种

human, rat

Small Molecule - Precursor

货号

说明

物种

左旋多巴, ≥98% (TLC),

物种

mouse, human, rat

3,4-二羟基- DL- 苯丙氨酸, ,

物种

mouse, human, rat

Proteins

货号

说明

物种

Dopamine D4 Receptor, control peptide for AB1789/AB1789P, ,

物种

rat

esiRNA

货号

说明

物种

MISSION^® esiRNA, targeting mouse Drd4,

物种

mouse