CN

DRD3

dopamine receptor D3

别名:

D3DR, ETM1, FET1

物种:

Human DRD3 (1814), Mouse Drd3 (13490), Rat Drd3 (29238), Zebrafish drd3 (282554), chicken DRD3 (770757), Horse DRD3 (100061160), domestic cat DRD3 (101092878), dog DRD3 (487984), sheep DRD3 (101103110), cow DRD3 (537043) ...展开

UniProtKB ID:

P35462, A1A4V5, Q4VBM8

基因ID:

Human(1814) Summary: This gene encodes the D3 subtype of the five (D1-D5) dopamine receptors. The activity of the D3 subtype receptor is mediated by G proteins which inhibit adenylyl cyclase. This receptor is localized to the limbic areas of the brain, which are associated with cognitive, emotional, and endocrine functions. Genetic variation in this gene may be associated with susceptibility to hereditary essential tremor 1. Alternative splicing of this gene results in transcript variants encoding different isoforms, although some variants may be subject to nonsense-mediated decay (NMD). [provided by RefSeq, Jul 2008]
Mouse(13490) dopamine receptor D3
Rat(29238) dopamine receptor D3
Zebrafish(282554) dopamine receptor D3
chicken(770757) dopamine receptor D3
Horse(100061160) dopamine receptor D3
domestic cat(101092878) dopamine receptor D3
dog(487984) dopamine receptor D3
sheep(101103110) dopamine receptor D3
cow(537043) dopamine receptor D3
naked mole-rat(101713857) dopamine receptor D3
domestic guinea pig(100716075) dopamine receptor D3

产品 (97)
同行评审论文 (220)

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Small Molecule - Agonist

货号

说明

物种

L-Dopa乙酯, ≥98% (HPLC),

物种

human

左旋多巴, certified reference material, TraceCERT^®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland,

物种

human

(±)-7-Hydroxy-2-(di-n-propylamino)tetralin hydrobromide, ,

物种

human

吡贝地尔马来酸盐, ,

物种

human

cis-8-Hydroxy-3-(n-propyl)-1,2,3a,4,5,9b-hexahydro-1H-benz[e]indole hydrobromide, ≥98% (HPLC), solid,

物种

human

Small Molecule - Antagonist

货号

说明

物种

Oxatomide, ≥99%,

物种

human

U116

U-99194 maleate salt, ≥98% (HPLC), solid,

物种

human

L135

L-741,626, ≥98% (HPLC),

物种

human

氯丙嗪盐酸盐, VETRANAL^®, analytical standard,

物种

human

氯丙嗪盐酸盐, meets USP testing specifications,

物种

human

Antibodies

货号

说明

物种反应性

应用

Anti-DRD3 / DOPAMINE antibody produced in rabbit, affinity isolated antibody,

物种反应性

dog, hamster, horse, human, monkey, mouse, pig

应用

immunohistochemistry

Anti-Dopamine Receptor D3 (DRD3) Antibody, clone 5L1P4, Rabbit Monoclonal, ,

物种反应性

human, rat

应用

western blot

Anti-Dopamine D3 Receptor Antibody, cytoplasmic domain, Chemicon^®, from rabbit,

物种反应性

human

应用

ELISA
immunohistochemistry
western blot

抗-多巴胺D3受体抗体，胞浆域, Chemicon^®, from rabbit,

物种反应性

mouse, rat

应用

ELISA
immunohistochemistry
western blot

Anti-Dopamine D₃ Receptor Rabbit pAb, lyophilized, Calbiochem^®,

物种反应性

human, rat

应用

Small Molecule - Inhibitor

货号

说明

物种

D052

GBR 12909 二盐酸盐, solid, ≥98% (HPLC),

物种

human

Amoxapine, 1.0 mg/mL in methanol, certified reference material, Cerilliant^®,

物种

human

阿莫沙平, Pharmaceutical Secondary Standard; Certified Reference Material,

物种

human

Amoxapine, United States Pharmacopeia (USP) Reference Standard,

物种

human

A129

Amoxapine, ,

物种

human

Small Molecule - Metabolite

货号

说明

物种

3-羟基-4-甲氧基苯乙胺盐酸盐, ,

物种

human

3-甲氧基酪胺盐酸盐, ≥95.5%, crystalline,

物种

human

Small Molecule - Mixed Agonist/Antagonist

货号

说明

物种

BP897, >98% (HPLC), solid,

物种

human, rat

氟哌啶醇, powder,

物种

human, rat

氯氮平标准液, ,

物种

human, rat

Small Molecule - Precursor

货号

说明

物种

左旋多巴, ≥98% (TLC),

物种

mouse, human, rat

3,4-二羟基- DL- 苯丙氨酸, ,

物种

mouse, human, rat

Proteins

货号

说明

物种

D181

D₃ Dopamine Receptor from rat, recombinant, expressed in E. coli, membrane suspension,

物种

rat

esiRNA

货号

说明

物种

MISSION^® esiRNA, targeting human DRD3,

物种

human