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Merck
CN

DRD4

dopamine receptor D4

别名:
D4DR
物种:
Human DRD4 (1815), Mouse Drd4 (13491), Rat Drd4 (25432), naked mole-rat Drd4 (101708437), dog DRD4 (448805), domestic guinea pig Drd4 (100733356), dog DRD4 (607223), chicken DRD4 (423016)
UniProtKB ID:
P21917, B0M0J7, Q7Z7Q5, Q8NGM5
基因ID:
  • Human(1815) Summary: This gene encodes the D4 subtype of the dopamine receptor. The D4 subtype is a G-protein coupled receptor which inhibits adenylyl cyclase. It is a target for drugs which treat schizophrenia and Parkinson disease. Mutations in this gene have been associated with various behavioral phenotypes, including autonomic nervous system dysfunction, attention deficit/hyperactivity disorder, and the personality trait of novelty seeking. This gene contains a polymorphic number (2-10 copies) of tandem 48 nt repeats; the sequence shown contains four repeats. [provided by RefSeq, Jul 2008]
  • Mouse(13491) dopamine receptor D4
  • Rat(25432) dopamine receptor D4
  • naked mole-rat(101708437) dopamine receptor D4
  • dog(448805) dopamine receptor D4
  • domestic guinea pig(100733356) dopamine receptor D4
  • dog(607223) dopamine receptor D4
  • chicken(423016) dopamine receptor D4

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Small Molecule - Agonist

产品编号
说明
物种
A1237
普拉克索 二盐酸盐, >98% (HPLC), powder,
物种
human
PHR1633
盐酸罗匹尼罗, Pharmaceutical Secondary Standard; Certified Reference Material,
物种
human
1605205
罗匹尼罗 盐酸盐, United States Pharmacopeia (USP) Reference Standard,
物种
human
Y0001773
罗匹尼罗 盐酸盐, European Pharmacopoeia (EP) Reference Standard,
物种
human
Y0002019
峰鉴别3用罗匹尼罗, European Pharmacopoeia (EP) Reference Standard,
物种
human

Small Molecule - Antagonist

产品编号
说明
物种
L131
L-745,870 hydrochloride, ,
物种
human
U115
U-101958 maleate salt, solid,
物种
human
L135
L-741,626, ≥98% (HPLC),
物种
human
C-904
氯丙嗪盐酸盐标准液 盐酸盐, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®,
物种
human
31679
氯丙嗪 盐酸盐, VETRANAL®, analytical standard,
物种
human

Antibodies

产品编号
说明
物种反应性
应用
MABN125
Anti-DRD4 Antibody, clone 2B9, clone 2B9, from mouse,
物种反应性
human, mouse, rat
应用
immunocytochemistry
western blot
AB1787P
Anti-Dopamine D4 Receptor Antibody, extracellular domain, Chemicon®, from rabbit,
物种反应性
mouse
应用
ELISA
western blot
HPA062682
Anti-Drd4 Antibody Produced In Rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunofluorescence
324405
Anti-Dopamine D4 Receptor Rabbit pAb, lyophilized, Calbiochem®,
物种反应性
human, rat
应用

Small Molecule - Inhibitor

产品编号
说明
物种
D052
GBR 12909 二盐酸盐, solid, ≥98% (HPLC),
物种
human
A-123
Amoxapine, 1.0 mg/mL in methanol, certified reference material, Cerilliant®,
物种
human
1031401
Amoxapine, United States Pharmacopeia (USP) Reference Standard,
物种
human
PHR1841
阿莫沙平, Pharmaceutical Secondary Standard; Certified Reference Material,
物种
human
A129
Amoxapine, ,
物种
human

Small Molecule - Metabolite

产品编号
说明
物种
H3132
3-羟基-4-甲氧基苯乙胺 盐酸盐, ,
物种
human
M4251
3-甲氧基酪胺 盐酸盐, ≥95.5%, crystalline,
物种
human

Small Molecule - Mixed Agonist/Antagonist

产品编号
说明
物种
B9308
BP897, >98% (HPLC), solid,
物种
human, rat
H1512
氟哌啶醇, powder,
物种
human, rat
C6305
氯氮平标准液, ,
物种
human, rat

Small Molecule - Precursor

产品编号
说明
物种
D9628
左旋多巴, ≥98% (TLC),
物种
mouse, human, rat
D9503
3,4-二羟基- DL- 苯丙氨酸, ,
物种
mouse, human, rat

Proteins

产品编号
说明
物种
AG222
Dopamine D4 Receptor, control peptide for AB1789/AB1789P, ,
物种
rat

esiRNA

产品编号
说明
物种
EMU028911
MISSION® esiRNA, targeting mouse Drd4,
物种
mouse