Merck
CN

ESR2

estrogen receptor 2 (ER beta)

别名:
ER-BETA, ESR-BETA, ESRB, ESTRB, Erb, NR3A2
物种:
UniProtKB ID:
基因ID:
  • Human(2100) Summary: This gene encodes a member of the family of estrogen receptors and superfamily of nuclear receptor transcription factors. The gene product contains an N-terminal DNA binding domain and C-terminal ligand binding domain and is localized to the nucleus, cytoplasm, and mitochondria. Upon binding to 17beta-estradiol or related ligands, the encoded protein forms homo- or hetero-dimers that interact with specific DNA sequences to activate transcription. Some isoforms dominantly inhibit the activity of other estrogen receptor family members. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been fully characterized. [provided by RefSeq, Jul 2008]
  • Mouse(13983) estrogen receptor 2 (beta)
  • Rat(25149) estrogen receptor 2 (ER beta)
  • dog(403639) estrogen receptor 2 (ER beta)
  • chicken(395575) estrogen receptor 2 (ER beta)
  • domestic guinea pig(100731304) estrogen receptor 2 (ER beta)
  • Domestic Rabbit(100346748) estrogen receptor 2 (ER beta)
  • domestic cat(101086317) estrogen receptor 2 (ER beta)
  • Horse(100033964) estrogen receptor 2 (ER beta)
  • cow(281146) estrogen receptor 2 (ER beta)
  • Goat(100860823) estrogen receptor 2 (ER beta)
  • sheep(443066) estrogen receptor 2 (ER beta)

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Small Molecule - Activator

货号
说明
物种
β-烟酰胺腺嘌呤二核苷酸 水合物, ≥96.5% (HPLC), ≥96.5% (spectrophotometric assay), from yeast,
物种
human
β-烟酰胺腺嘌呤二核苷酸 水合物, ≥99%,
物种
human
β-烟酰胺腺嘌呤二核苷酸, pkg of 10 mg (per vial),
物种
human
β-烟酰胺腺嘌呤二核苷酸 水合物, ≥95% (HPLC),
物种
human
β-烟酰胺腺嘌呤二核苷酸 水合物, BioUltra, ≥98%, from yeast,
物种
human

Small Molecule - Agonist

货号
说明
物种
ERB-041, ≥98% (HPLC),
物种
human
4-{1-Ethyl-2-[4-(phosphonooxy)phenyl]-1-butenyl}phenyl dihydrogen phosphate, ,
物种
human

Small Molecule - Allosteric Modulator

货号
说明
物种
Estramustine sodium phosphate, ,
物种
human

Small Molecule - Antagonist

货号
说明
物种
氟维司群, Vetec, reagent grade, >98%,
物种
human
4,4′-二羟基联苯, 97%,
物种
human
氰基联苯酚, 97%,
物种
human
香豆雌酚, ≥95.0% (HPLC),
物种
mouse, human, rat
香豆雌酚, BioReagent, suitable for fluorescence, ≥97.5% (HPLC),
物种
mouse, human, rat

Antibodies

货号
说明
物种反应性
应用
单克隆抗 ESR2 小鼠抗, ,
物种反应性
human, monkey, mouse
应用
ChIP
dot blot

flow cytometry

immunocytochemistry

immunofluorescence

immunohistochemistry

western blot
抗-雌激素受体-β 兔抗, affinity isolated antibody,
物种反应性
human, mouse, rat
应用
ELISA
immunofluorescence

western blot
抗雌激素受体β抗体,克隆68-4,兔单克隆, clone 68-4, Upstate®, from rabbit,
物种反应性
human
应用
immunoprecipitation (IP)
western blot
Anti-ESR2 antibody produced in rabbit, affinity isolated antibody,
物种反应性
human
应用
western blot
Anti-ESR2 antibody produced in rabbit, affinity isolated antibody,
物种反应性
bovine, human, mouse, pig, rat
应用
western blot

Cell Lines

货号
说明
物种
MCF10A CELLS ESR2 (-/-), ,
物种
human

Small Molecule - Mixed Agonist/Antagonist

货号
说明
物种
β-雌二醇, BioReagent, powder, suitable for cell culture,
物种
human, mouse, rat
β-雌二醇, ≥98%,
物种
human, mouse, rat
米非司酮, ≥98%,
物种
human, mouse, rat

esiRNA

货号
说明
物种
MISSION® 长非编码 esiRNA, targeting human ESR2,
物种
human