Merck
CN

GRIN1

glutamate receptor, ionotropic, N-methyl D-aspartate 1

别名:
GluN1, MRD8, NMDA1, NMDAR1, NR1
物种:
UniProtKB ID:
基因ID:
  • Human(2902) Summary: The protein encoded by this gene is a critical subunit of N-methyl-D-aspartate receptors, members of the glutamate receptor channel superfamily which are heteromeric protein complexes with multiple subunits arranged to form a ligand-gated ion channel. These subunits play a key role in the plasticity of synapses, which is believed to underlie memory and learning. Cell-specific factors are thought to control expression of different isoforms, possibly contributing to the functional diversity of the subunits. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2008]
  • Mouse(14810) glutamate receptor, ionotropic, NMDA1 (zeta 1)
  • Rat(24408) glutamate receptor, ionotropic, N-methyl D-aspartate 1
  • naked mole-rat(101720185) glutamate receptor, ionotropic, N-methyl D-aspartate 1
  • Horse(100059861) glutamate receptor, ionotropic, N-methyl D-aspartate 1
  • chicken(404296) glutamate receptor, ionotropic, N-methyl D-aspartate 1
  • sheep(443281) glutamate receptor, ionotropic, N-methyl D-aspartate 1
  • cow(100336579) glutamate receptor, ionotropic, N-methyl D-aspartate 1
  • domestic guinea pig(100301989) glutamate receptor, ionotropic, NMDA1 (zeta 1)
  • dog(494007) glutamate receptor, ionotropic, N-methyl D-aspartate 1

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Small Molecule - Agonist

货号
说明
物种
D -丝氨酸, ≥98% (TLC),
物种
human
精胺 四盐酸盐, powder or crystals,
物种
human
牛磺酸, ≥99%,
物种
human, rat
N-甲基- D -天冬氨酸, ≥98% (TLC), solid,
物种
human, rat
N-Acetyl-Asp-Glu, ≥97% (TLC),
物种
mouse, human, rat

Small Molecule - Allosteric Modulator

货号
说明
物种
阿坎酸钙, ≥98% (HPLC), powder,
物种
human
阿坎酸钙, United States Pharmacopeia (USP) Reference Standard, monograph mol wt. 400.48 (C10H20CaN2O8S2),
物种
human
阿坎酸钙, British Pharmacopoeia (BP) Reference Standard,
物种
human

Small Molecule - Antagonist

货号
说明
物种
MDL 105,519, ≥98% (HPLC), solid,
物种
rat, human
CP-101,606, ≥98% (HPLC),
物种
human
艾芬地尔 (+)-酒石酸盐, ,
物种
human
魁蛤素 硫酸盐, ,
物种
human
(±)-CPP, solid,
物种
rat, human

Antibodies

货号
说明
物种反应性
应用
抗-NMDAR1 兔抗, affinity isolated antibody,
物种反应性
human, mouse, rat
应用
ELISA
immunofluorescence

immunohistochemistry

western blot
Monoclonal Anti-Glun1-Nr1 antibody produced in mouse, clone S308-48, purified immunoglobulin,
物种反应性
human, mouse, rat
应用
immunocytochemistry
immunohistochemistry

western blot
Anti-NMDA Receptor 1/GRIN1 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
物种反应性
human, mouse
应用
ELISA
immunofluorescence
Anti-GRIN1 (Ab-897) antibody produced in rabbit, affinity isolated antibody,
物种反应性
human, mouse, rat
应用
immunofluorescence
Anti-NMDAR1 antibody produced in rabbit, affinity isolated antibody,
物种反应性
human, mouse, rat
应用
ELISA
immunohistochemistry

western blot

Small Molecule - Blocker

货号
说明
物种
N-(3,3-Diphenylpropyl)glycinamide, >98% (HPLC), solid,
物种
human
胍丁胺 硫酸盐, ≥97%, powder,
物种
human
奥芬那君 盐酸盐, ≥98.0% (AT),
物种
human
奥芬那君 盐酸盐, European Pharmacopoeia (EP) Reference Standard,
物种
human
奥芬那君 盐酸盐, European Pharmacopoeia (EP) Reference Standard,
物种
human

Small Molecule - Inhibitor

货号
说明
物种
牛磺酸, ≥99%,
物种
human, rat
喷他脒 羟乙基磺酸盐, powder,
物种
human
奥芬那君 盐酸盐, ≥98.0% (AT),
物种
human
奥芬那君 盐酸盐, European Pharmacopoeia (EP) Reference Standard,
物种
human
奥芬那君 盐酸盐, European Pharmacopoeia (EP) Reference Standard,
物种
human

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting human GRIN1,
物种
human
MISSION® esiRNA, targeting mouse Grin1,
物种
mouse