Merck
CN

HDAC4

histone deacetylase 4

别名:
AHO3, BDMR, HA6116, HD4, HDAC-4, HDAC-A, HDACA
物种:
UniProtKB ID:
基因ID:
  • Human(9759) Summary: Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3. [provided by RefSeq, Jul 2008]
  • Mouse(208727) histone deacetylase 4
  • Rat(363287) histone deacetylase 4
  • Zebrafish(568877) histone deacetylase 4
  • chicken(374207) histone deacetylase 4
  • sheep(101108012) histone deacetylase 4
  • fruit fly(32278) CG1770 gene product from transcript CG1770-RG
  • cow(517559) histone deacetylase 4
  • domestic guinea pig(100713301) histone deacetylase 4
  • naked mole-rat(101696612) histone deacetylase 4
  • dog(607662) histone deacetylase 4
  • domestic cat(101093384) histone deacetylase 4

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Antibodies

货号
说明
物种反应性
应用
Anti-HDAC4 (Ab-632) antibody produced in rabbit, affinity isolated antibody,
物种反应性
human, mouse, rat
应用
immunofluorescence
western blot
Anti-HDAC4 Antibody, serum, from rabbit,
物种反应性
human
应用
ChIP
immunocytochemistry

immunoprecipitation (IP)

western blot
Anti-HDAC4 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
物种反应性
human
应用
immunofluorescence
Anti-HDAC4 Antibody, clone 9A6E2, Rabbit Monoclonal, ,
物种反应性
human
应用
western blot
Anti-HDAC4 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunofluorescence
immunohistochemistry

western blot

Small Molecule - Inhibitor

货号
说明
物种
罗咪酯肽, ≥98% (HPLC),
物种
human
CI−994, ≥98% (HPLC), powder,
物种
human

Proteins

货号
说明
物种
HDAC-4 human, recombinant, expressed in baculovirus infected insect cells, ≥50% (SDS-PAGE),
物种
human

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting mouse Hdac4,
物种
mouse
MISSION® esiRNA, targeting human HDAC4,
物种
human