Merck
CN

HRAS

Harvey rat sarcoma viral oncogene homolog

别名:
C-BAS/HAS, C-H-RAS, C-HA-RAS1, CTLO, H-RASIDX, HAMSV, HRAS1, K-RAS, N-RAS, RASH1
物种:
UniProtKB ID:
基因ID:
  • Human(3265) Summary: This gene belongs to the Ras oncogene family, whose members are related to the transforming genes of mammalian sarcoma retroviruses. The products encoded by these genes function in signal transduction pathways. These proteins can bind GTP and GDP, and they have intrinsic GTPase activity. This protein undergoes a continuous cycle of de- and re-palmitoylation, which regulates its rapid exchange between the plasma membrane and the Golgi apparatus. Mutations in this gene cause Costello syndrome, a disease characterized by increased growth at the prenatal stage, growth deficiency at the postnatal stage, predisposition to tumor formation, mental retardation, skin and musculoskeletal abnormalities, distinctive facial appearance and cardiovascular abnormalities. Defects in this gene are implicated in a variety of cancers, including bladder cancer, follicular thyroid cancer, and oral squamous cell carcinoma. Multiple transcript variants, which encode different isoforms, have been identified for this gene. [provided by RefSeq, Jul 2008]
  • Rat(293621) Harvey rat sarcoma virus oncogene
  • dog(403735) v-Ha-ras Harvey rat sarcoma viral oncogene homolog
  • cow(100298939) v-Ha-ras Harvey rat sarcoma viral oncogene homolog
  • naked mole-rat(101716053) v-Ha-ras Harvey rat sarcoma viral oncogene homolog
  • chicken(396229) v-Ha-ras Harvey rat sarcoma viral oncogene homolog
  • domestic guinea pig(100735038) v-Ha-ras Harvey rat sarcoma viral oncogene homolog
  • sheep(101104357) v-Ha-ras Harvey rat sarcoma viral oncogene homolog

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Small Molecule - Antagonist

货号
说明
物种
鸟苷5′-三磷酸 钠盐 水合物, ≥95% (HPLC), powder,
物种
human
肌苷 5′-三磷酸盐 三钠盐, ≥95%,
物种
human
鸟苷5′-三磷酸 钠盐 溶液, HPLC purified, aqueous solution for RNA polymerase transcription,
物种
human
2′,3′-双脱氧鸟苷 5′-三磷酸 钠盐, ≥90% (HPLC),
物种
human
Erastin, ≥98% (HPLC),
物种
mouse, rat, human

Antibodies

货号
说明
物种反应性
应用
Monoclonal Anti-HRAS antibody produced in mouse, clone H-RAS-03,
物种反应性
human
应用
western blot
Anti-HRAS antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
proximity ligation assay
western blot
Anti-H-Ras Antibody, clone 3B13 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
物种反应性
human, mouse, rat
应用
ELISA
affinity binding assay

western blot
Anti-Ha-Ras Antibody, clone MC57, rabbit monoclonal, culture supernatant, clone MC57, from rabbit,
物种反应性
human, mouse, rat
应用
western blot
Anti-c-H-Ras (Ab-1) Mouse mAb (F235-1.7.1), liquid, clone F235-1.7.1, Calbiochem®,
物种反应性
human, mouse, rat
应用

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting human HRAS,
物种
human