Merck
CN

HTR2A

5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled

别名:
5-HT2A, HTR2
物种:
Human HTR2A (3356), Mouse Htr2a (15558), Rat Htr2a (29595), dog HTR2A (403882), naked mole-rat Htr2a (101708395), Horse HTR2A (100009685), chicken HTR2A (428070), domestic guinea pig Htr2a (100135545), domestic cat HTR2A (101081108), cow HTR2A (407230)
UniProtKB ID:
P28223, B2RAC5, B4DZ79, F5GWE8, Q5T8C0
基因ID:
  • Human(3356) Summary: This gene encodes one of the receptors for serotonin, a neurotransmitter with many roles. Mutations in this gene are associated with susceptibility to schizophrenia and obsessive-compulsive disorder, and are also associated with response to the antidepressant citalopram in patients with major depressive disorder (MDD). MDD patients who also have a mutation in intron 2 of this gene show a significantly reduced response to citalopram as this antidepressant downregulates expression of this gene. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]
  • Mouse(15558) 5-hydroxytryptamine (serotonin) receptor 2A
  • Rat(29595) 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
  • dog(403882) 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
  • naked mole-rat(101708395) 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
  • Horse(100009685) 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
  • chicken(428070) 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
  • domestic guinea pig(100135545) 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
  • domestic cat(101081108) 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
  • cow(407230) 5-hydroxytryptamine (serotonin) receptor 2A

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Small Molecule - Agonist

货号
说明
物种
D101
（±）-DOI 盐酸盐, ≥98% (HPLC), solid,
物种
human
A-119
阿立哌唑 溶液, 1.0 mg/mL (50:50 Methanol/Water with 1% 1N HCl), ampule of 1 mL, certified reference material, Cerilliant®,
物种
human
M110
α-甲基血清素 马来酸盐, ≥98% (HPLC),
物种
human
N7261
去甲替林 盐酸盐, ≥98% (HPLC), powder,
物种
human
T6154
曲唑酮 盐酸盐, ≥99% (HPLC), powder,
物种
human

Small Molecule - Allosteric Modulator

货号
说明
物种
D9190
DCEBIO, ≥98% (HPLC), solid,
物种
human

Small Molecule - Antagonist

货号
说明
物种
PHR1724
氟哌啶醇, Pharmaceutical Secondary Standard; Certified Reference Material,
物种
human
M3324
M100907, ≥98% (HPLC),
物种
human
H-030
Haloperidol solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
物种
human
D206709
2,2-二苯基乙胺, 96%,
物种
rat
1303002
氟哌啶醇, United States Pharmacopeia (USP) Reference Standard,
物种
human

Antibodies

货号
说明
物种反应性
应用
MABN1595
抗-5-羟色胺受体2A/HTR2A抗体，克隆9B11.1, clone 9B11.1, from mouse,
物种反应性
human, mouse, rat
应用
immunohistochemistry
western blot
PC176
Anti-Serotonin 2A (5-HT2A) Receptor (22-41) Rabbit pAb, liquid, Calbiochem®,
物种反应性
mouse, rat, sheep
应用
SAB2101106
Anti-HTR2A antibody produced in rabbit, affinity isolated antibody,
物种反应性
human
应用
western blot
SAB4501474
Anti-5-HT-2A antibody produced in rabbit, affinity isolated antibody,
物种反应性
human
应用
ELISA
immunofluorescence
immunohistochemistry
SAB4301791
抗-HTR2A, affinity isolated antibody,
物种反应性
human, rat
应用
immunohistochemistry
western blot

Small Molecule - Blocker

货号
说明
物种
T6154
曲唑酮 盐酸盐, ≥99% (HPLC), powder,
物种
human
P1793
匹莫齐特, ,
物种
human, mouse, rat
T3146
三甲丙咪嗪标准液 马来酸盐, ≥98% (TLC), powder,
物种
human

Small Molecule - Inhibitor

货号
说明
物种
T-030
Trazodone hydrochloride solution, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®,
物种
human
BP591
盐酸曲唑酮杂质标准品, British Pharmacopoeia (BP) Reference Standard,
物种
human
BP590
曲唑酮 盐酸盐, British Pharmacopoeia (BP) Reference Standard,
物种
human
1673500
曲唑酮 盐酸盐, United States Pharmacopeia (USP) Reference Standard,
物种
human
N5536
Nefazodone hydrochloride, ≥98% (HPLC), solid,
物种
human

Small Molecule - Ligand

货号
说明
物种
M1514
Nω-Methyl-5-hydroxy­trypt­amine oxalate salt, ≥90% (HPLC),
物种
human

Small Molecule - Metabolite

货号
说明
物种
H8876
5-羟基吲哚-3-乙酸, ≥98% (HPLC), crystalline,
物种
human

Small Molecule - Mixed Agonist/Antagonist

货号
说明
物种
M8046
米非司酮, ≥98%,
物种
human, mouse, rat
H1512
氟哌啶醇, powder,
物种
human, rat
C6305
氯氮平标准液, ,
物种
human, rat

Small Molecule - Precursor

货号
说明
物种
H9772
5-羟基L-色氨酸, powder,
物种
human

esiRNA

货号
说明
物种
EMU023531
MISSION® esiRNA, targeting mouse Htr2a,
物种
mouse