Merck
CN

HTR2B

5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled

别名:
5-HT(2B), 5-HT2B
物种:
UniProtKB ID:
基因ID:
  • Human(3357) Summary: This gene encodes one of the several different receptors for 5-hydroxytryptamine (serotonin) that belongs to the G-protein coupled receptor 1 family. Serotonin is a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. Serotonin receptors mediate many of the central and peripheral physiologic functions of serotonin, including regulation of cardiovascular functions and impulsive behavior. Population and family-based analyses of a minor allele (glutamine-to-stop substitution, designated Q20*) which blocks expression of this protein, and knockout studies in mice, suggest a role for this gene in impulsivity. However, other factors, such as elevated testosterone levels, may also be involved. [provided by RefSeq, Oct 2011]
  • Mouse(15559) 5-hydroxytryptamine (serotonin) receptor 2B
  • Rat(29581) 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
  • chicken(395581) 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
  • Zebrafish(751784) 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
  • dog(403881) 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
  • cow(407135) 5-hydroxytryptamine (serotonin) receptor 2B
  • Horse(100057052) 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
  • domestic cat(101095762) 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
  • Domestic Rabbit(100343392) 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
  • sheep(101106827) 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
  • naked mole-rat(101699201) 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
  • domestic guinea pig(100135546) 5-hydroxytryptamine (serotonin) receptor 2B

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Small Molecule - Agonist

货号
说明
物种
BW 723C86, ≥98% (HPLC),
物种
human
(±)-DOI 盐酸盐, ≥98% (HPLC), solid,
物种
human
α-甲基血清素 马来酸盐, ≥98% (HPLC),
物种
human
去甲替林 盐酸盐, ≥98% (HPLC), powder,
物种
human
5-甲氧色胺 盐酸盐, crystalline,
物种
human

Small Molecule - Allosteric Modulator

货号
说明
物种
DCEBIO, ≥98% (HPLC), solid,
物种
human

Small Molecule - Antagonist

货号
说明
物种
酮色林 (+)-酒石酸盐, ≥97%, solid,
物种
human
环苯扎林 盐酸盐, ,
物种
human
赛庚啶 盐酸盐 倍半水合物, ≥98% (TLC), solid,
物种
human
Octoclothepin 马来酸盐, solid,
物种
human
4,4′-二甲氧基三苯甲基氯, ≥97.0% (HPLC),
物种
rat, human

Antibodies

货号
说明
物种反应性
应用
抗-HTR2B 兔抗, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunofluorescence
immunohistochemistry
Anti-HTR2B antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
物种反应性
human
应用
immunofluorescence
Monoclonal Anti-HTR2B antibody produced in mouse, clone 4F3, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
ELISA
Anti-HTR2B antibody produced in rabbit, affinity isolated antibody,
物种反应性
human
应用
ELISA
immunofluorescence

western blot
Anti-5-HT-2B antibody produced in rabbit, affinity isolated antibody,
物种反应性
human
应用
ELISA
immunofluorescence

immunohistochemistry

western blot

Small Molecule - Blocker

货号
说明
物种
三甲丙咪嗪标准液 马来酸盐, ≥98% (TLC), powder,
物种
human

Small Molecule - Inhibitor

货号
说明
物种
去甲替林 盐酸盐, ≥98% (HPLC), powder,
物种
human
Amoxapine, ,
物种
human
R-(−)-Fluoxetine hydrochloride, >98% (HPLC), solid,
物种
human
氟西汀 盐酸盐, solid,
物种
human
氢溴酸西酞普兰 氢溴酸盐, ≥98% (HPLC),
物种
human

Small Molecule - Ligand

货号
说明
物种
Nω-Methyl-5-hydroxy­trypt­amine oxalate salt, ≥90% (HPLC),
物种
human

Small Molecule - Metabolite

货号
说明
物种
5-羟基吲哚-3-乙酸, ≥98% (HPLC), crystalline,
物种
human

Small Molecule - Mixed Agonist/Antagonist

货号
说明
物种
米非司酮, ≥98%,
物种
human, mouse, rat
氯氮平标准液, ,
物种
human, rat

Small Molecule - Precursor

货号
说明
物种
5-羟基L-色氨酸, powder,
物种
human

Proteins

货号
说明
物种
PrEST Antigen HTR2B, Prestige Antigens Powered by Atlas Antibodies, buffered aqueous solution,
物种
human

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting human HTR2B,
物种
human