CN
HEXA
hexosaminidase A (alpha polypeptide)
别名:
TSD
物种:
Human HEXA (3073), Mouse Hexa (15211), Rat Hexa (300757), chicken HEXA (415320), Zebrafish hexa (323613), domestic guinea pig Hexa (100712955), naked mole-rat Hexa (101718368), domestic cat HEXA (101091627), dog HEXA (487633), Horse HEXA (100063584) ...展开
UniProtKB ID:
基因ID:
- Human(3073) Summary: This gene encodes the alpha subunit of the lysosomal enzyme beta-hexosaminidase that, together with the cofactor GM2 activator protein, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Beta-hexosaminidase is composed of two subunits, alpha and beta, which are encoded by separate genes. Both beta-hexosaminidase alpha and beta subunits are members of family 20 of glycosyl hydrolases. Mutations in the alpha or beta subunit genes lead to an accumulation of GM2 ganglioside in neurons and neurodegenerative disorders termed the GM2 gangliosidoses. Alpha subunit gene mutations lead to Tay-Sachs disease (GM2-gangliosidosis type I). [provided by RefSeq, Jul 2009]
- Mouse(15211) hexosaminidase A
- Rat(300757) hexosaminidase A
- chicken(415320) hexosaminidase A (alpha polypeptide)
- Zebrafish(323613) hexosaminidase A (alpha polypeptide)
- domestic guinea pig(100712955) hexosaminidase A (alpha polypeptide)
- naked mole-rat(101718368) hexosaminidase A (alpha polypeptide)
- domestic cat(101091627) hexosaminidase A (alpha polypeptide)
- dog(487633) hexosaminidase A (alpha polypeptide)
- Horse(100063584) hexosaminidase A (alpha polypeptide)
- sheep(100145856) hexosaminidase A (alpha polypeptide)
- cow(504468) hexosaminidase A (alpha polypeptide)
- Domestic Rabbit(100008950) hexosaminidase A (alpha polypeptide)
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ELISA
货号
说明
物种
Antibodies
货号
说明
物种反应性
应用
Anti-HEXA (C-terminal) antibody produced in rabbit, affinity isolated antibody,
物种反应性
bovine, canine, guinea pig, horse, human, mouse, pig, rabbit, sheep
应用
immunohistochemistry
western blot
western blot
Anti-HEXA antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunofluorescence
Anti-HEXA antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
western blot
Monoclonal Anti-HEXA antibody produced in mouse, clone 3D1, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
ELISA
immunofluorescence
western blot
immunofluorescence
western blot
Small Molecule - Inhibitor
esiRNA
货号
说明
物种