Merck
CN

IL6R

interleukin 6 receptor

别名:
CD126, IL-6R-1, IL-6RA, IL6Q, IL6RA, IL6RQ, gp80
物种:
UniProtKB ID:
基因ID:
  • Human(3570) Summary: This gene encodes a subunit of the interleukin 6 (IL6) receptor complex. Interleukin 6 is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in the immune response. The IL6 receptor is a protein complex consisting of this protein and interleukin 6 signal transducer (IL6ST/GP130/IL6-beta), a receptor subunit also shared by many other cytokines. Dysregulated production of IL6 and this receptor are implicated in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer. Alternatively spliced transcript variants encoding distinct isoforms have been reported. A pseudogene of this gene is found on chromosome 9.[provided by RefSeq, May 2011]
  • Rat(24499) interleukin 6 receptor
  • domestic guinea pig(100730490) interleukin 6 receptor
  • domestic cat(101085689) interleukin 6 receptor
  • Zebrafish(100135755) interleukin 6 receptor
  • dog(612271) interleukin 6 receptor
  • cow(507359) interleukin 6 receptor
  • sheep(101103369) interleukin 6 receptor
  • naked mole-rat(101704925) interleukin 6 receptor

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

货号
说明
物种反应性
应用
Monoclonal Anti-IL6R antibody produced in mouse, clone 1E11, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
ELISA
western blot
Anti-IL6R antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
western blot
Monoclonal Anti-IL6R antibody produced in mouse, clone 2G6, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
ELISA
western blot
Anti-CD126 Antibody, clone B-R6, clone B-R6, Chemicon®, from mouse,
物种反应性
human
应用
ELISA
flow cytometry

immunohistochemistry

immunoprecipitation (IP)

Proteins

货号
说明
物种
IL-6受体 人, recombinant, expressed in CHO cells, ≥95% (SDS-PAGE), ≥95% (HPLC), suitable for cell culture,
物种
human

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting human IL6R,
物种
human