Merck
CN

MMP8

matrix metallopeptidase 8 (neutrophil collagenase)

别名:
CLG1, HNC, MMP-8, PMNL-CL
物种:
UniProtKB ID:
基因ID:
  • Human(4317) Summary: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the enzyme encoded by this gene is stored in secondary granules within neutrophils and is activated by autolytic cleavage. Its function is degradation of type I, II and III collagens. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. [provided by RefSeq, Jul 2008]
  • Mouse(17394) matrix metallopeptidase 8
  • Rat(63849) matrix metallopeptidase 8
  • domestic guinea pig(100724670) matrix metallopeptidase 8 (neutrophil collagenase)
  • naked mole-rat(101716969) matrix metallopeptidase 8 (neutrophil collagenase)
  • sheep(101120601) matrix metallopeptidase 8 (neutrophil collagenase)
  • domestic cat(101080995) matrix metallopeptidase 8 (neutrophil collagenase)
  • Horse(100069005) matrix metallopeptidase 8 (neutrophil collagenase)
  • cow(100336575) matrix metallopeptidase 8 (neutrophil collagenase)
  • dog(489429) matrix metallopeptidase 8 (neutrophil collagenase)

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ELISA

货号
说明
物种
人类 MMP-8 ELISA 试剂盒, for serum, plasma, conditioned medium, urine,
物种
human
大鼠MMP-8 ELISA试剂盒, for serum, plasma, cell culture supernatant,
物种
mouse

Antibodies

货号
说明
物种反应性
应用
Anti-MMP8 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution, Ab1,
物种反应性
human
应用
immunohistochemistry
Anti-MMP8 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution, Ab2,
物种反应性
human
应用
immunohistochemistry

Small Molecule - Inhibitor

货号
说明
物种
α-六噻吩, ,
物种
human, rat
PD166793 hydrate, ≥98% (HPLC),
物种
human, rat, mouse
马立马司他, ≥98% (HPLC),
物种
human, rat, mouse
CP-101537, ≥98% (HPLC),
物种
human, rat, mouse
CP-471474, ≥98% (HPLC),
物种
human, rat, mouse

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting human MMP8,
物种
human