CN
MAPK10
mitogen-activated protein kinase 10
别名:
JNK3, JNK3A, PRKM10, SAPK1b, p493F12, p54bSAPK
物种:
Human MAPK10 (5602), Mouse Mapk10 (26414), Rat Mapk10 (25272), Horse MAPK10 (100052608), Domestic Rabbit MAPK10 (100337999), domestic guinea pig Mapk10 (100718766), Zebrafish mapk10 (569698), sheep MAPK10 (101120665), dog MAPK10 (478464), domestic cat MAPK10 (101101463) ...展开
UniProtKB ID:
基因ID:
- Human(5602) Summary: The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This protein is a neuronal-specific form of c-Jun N-terminal kinases (JNKs). Through its phosphorylation and nuclear localization, this kinase plays regulatory roles in the signaling pathways during neuronal apoptosis. Beta-arrestin 2, a receptor-regulated MAP kinase scaffold protein, is found to interact with, and stimulate the phosphorylation of this kinase by MAP kinase kinase 4 (MKK4). Cyclin-dependent kianse 5 can phosphorylate, and inhibit the activity of this kinase, which may be important in preventing neuronal apoptosis. Four alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
- Mouse(26414) mitogen-activated protein kinase 10
- Rat(25272) mitogen activated protein kinase 10
- Horse(100052608) mitogen-activated protein kinase 10
- Domestic Rabbit(100337999) mitogen-activated protein kinase 10
- domestic guinea pig(100718766) mitogen-activated protein kinase 10
- Zebrafish(569698) mitogen-activated protein kinase 10
- sheep(101120665) mitogen-activated protein kinase 10
- dog(478464) mitogen-activated protein kinase 10
- domestic cat(101101463) mitogen-activated protein kinase 10
- naked mole-rat(101712980) mitogen-activated protein kinase 10
- cow(537631) mitogen-activated protein kinase 10
- chicken(422592) mitogen-activated protein kinase 10
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Antibodies
货号
说明
物种反应性
应用
ANTI-MAPK10 antibody produced in mouse, clone 3A3-1A8, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
ELISA
western blot
western blot
Anti-MAPK10 antibody produced in rabbit, affinity isolated antibody,
物种反应性
human, mouse, rat
应用
ELISA
western blot
western blot
Monoclonal Anti-MAPK10 antibody produced in mouse, clone 3B9, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
ELISA
western blot
western blot
Anti-JNK3/SAPK1b Antibody, clone C05T, rabbit monoclonal, culture supernatant, clone C05T, from rabbit,
物种反应性
human, rat
应用
western blot
Small Molecule - Inhibitor
Proteins
货号
说明
物种
JNK3/SAPK1b Protein, active, 10 µg, Active, N-terminal His6 tagged, recombinant, full length human JNK3/SAPK1b, for use in Kinase Assays.,
物种
human
JNK3/SAPK1b Protein, inactive, 50 g, Unactive, N-terminal His6-tagged recombinant human JNK3/SAPK1b, for use in Kinase Assays.,
物种
human
JNK3, active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
物种
human
esiRNA
货号
说明
物种