Merck
CN

NFATC1

nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1

别名:
NF-ATC, NFAT2, NFATc
物种:
UniProtKB ID:
基因ID:
  • Human(4772) Summary: The product of this gene is a component of the nuclear factor of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation, and an inducible nuclear component. Proteins belonging to this family of transcription factors play a central role in inducible gene transcription during immune response. The product of this gene is an inducible nuclear component. It functions as a major molecular target for the immunosuppressive drugs such as cyclosporin A. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. Different isoforms of this protein may regulate inducible expression of different cytokine genes. [provided by RefSeq, Jul 2013]
  • Mouse(18018) nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 1
  • Rat(100361818) nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
  • Zebrafish(568315) nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
  • dog(483925) nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
  • Domestic Rabbit(100352378) nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
  • domestic guinea pig(100730044) nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
  • cow(511224) nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
  • sheep(101108097) nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
  • naked mole-rat(101697946) nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
  • Horse(100065378) nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
  • chicken(420815) nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
  • domestic cat(101101259) nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1

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Small Molecule - Antagonist

货号
说明
物种
2,2′:5′,2′′:5′′,2′′′-四噻吩, 96%,
物种
human, rat, mouse

Antibodies

货号
说明
物种反应性
应用
Anti-NFATc1 Antibody, clone 7A6, clone 7A6, from mouse,
物种反应性
human, mouse
应用
flow cytometry
immunofluorescence

western blot
Anti-NFATc1 Antibody, clone 1O16 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
物种反应性
human
应用
ELISA
affinity binding assay

immunocytochemistry

immunohistochemistry

western blot
Anti-NFAT2 Antibody, clone 4I9P10, Rabbit Monoclonal, ,
物种反应性
mouse
应用
western blot
Anti-NFATC1 (ab1) antibody produced in rabbit, affinity isolated antibody,
物种反应性
human
应用
immunohistochemistry
western blot
Anti-NFATC1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
物种反应性
human
应用
immunofluorescence

Small Molecule - Inhibitor

货号
说明
物种
NFAT 抑制剂, >96% (HPLC), solid,
物种
mouse, human
2,2′:5′,2′′:5′′,2′′′-四噻吩, 96%,
物种
human, rat, mouse

Proteins

货号
说明
物种
NFATC1, GST tagged human, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
物种
human

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting mouse Nfatc1,
物种
mouse
MISSION® esiRNA, targeting human NFATC1,
物种
human