Merck
CN

PARP1

poly (ADP-ribose) polymerase 1

别名:
ADPRT, ADPRT 1, ADPRT1, ARTD1, PARP, PARP-1, PPOL, pADPRT-1
物种:
Human PARP1 (142), Mouse Parp1 (11545), Rat Parp1 (25591), Thale Cress PARP1 (817690), chicken PARP1 (396199), Zebrafish parp1 (560788), sheep PARP1 (100135697), domestic cat PARP1 (101081434), Horse PARP1 (100058523), dog PARP1 (490385) ...展开
UniProtKB ID:
P09874, B1ANJ4, Q8IUZ9
基因ID:
  • Human(142) Summary: This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes. [provided by RefSeq, Jul 2008]
  • Mouse(11545) poly (ADP-ribose) polymerase family, member 1
  • Rat(25591) poly (ADP-ribose) polymerase 1
  • Thale Cress(817690) poly [ADP-ribose] polymerase 2
  • chicken(396199) poly (ADP-ribose) polymerase 1
  • Zebrafish(560788) poly (ADP-ribose) polymerase family, member 1
  • sheep(100135697) poly (ADP-ribose) polymerase 1
  • domestic cat(101081434) poly (ADP-ribose) polymerase 1
  • Horse(100058523) poly (ADP-ribose) polymerase 1
  • dog(490385) poly (ADP-ribose) polymerase 1
  • domestic guinea pig(100733925) poly (ADP-ribose) polymerase 1
  • naked mole-rat(101703207) poly (ADP-ribose) polymerase 1
  • cow(286764) poly (ADP-ribose) polymerase 1

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Antibodies

货号
说明
物种反应性
应用
MABC547
抗-聚ADP-核糖抗体，克隆10H, clone 10H, from mouse,
物种反应性
human
应用
immunofluorescence
immunoprecipitation (IP)
western blot
WH0000142M1
Monoclonal Anti-PARP1 antibody produced in mouse, clone 3G4, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
ELISA
immunofluorescence
western blot
HPA045168
Anti-PARP1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunofluorescence
immunohistochemistry
western blot
SAB4500487
Anti-PARP (Cleaved-Asp214) antibody produced in rabbit, affinity isolated antibody,
物种反应性
human, mouse
应用
ELISA
western blot
PLA0184
Rabbit anti-PARP1 Antibody, Affinity Purified, Powered by Bethyl Laboratories, Inc.,
物种反应性
human
应用
western blot

Small Molecule - Inhibitor

货号
说明
物种
135828
苯甲酰胺, 99%,
物种
human
A0788
3-氨基苯甲酰胺, ≥99% (TLC),
物种
mouse
399337
苯甲酰胺, purified by sublimation, ≥99.5%,
物种
human
299634
6-(5H)-菲啶酮, technical grade,
物种
human
N0636
烟酰胺, BioReagent, suitable for cell culture, suitable for insect cell culture,
物种
human

Proteins

货号
说明
物种
SRP0192
PARP1 Active human, recombinant, expressed in baculovirus infected insect cells, ≥80% (SDS-PAGE),
物种
human
AMAB90959
单克隆抗-PARP1 小鼠抗, Prestige Antibodies® Powered by Atlas Antibodies, clone CL2220, purified immunoglobulin, buffered aqueous glycerol solution,
物种
human
P0996
PARP-1 人, recombinant, expressed in E. coli,
物种
human
AMAB90960
Monoclonal Anti-PARP1, Prestige Antibodies® Powered by Atlas Antibodies, clone CL2209, purified immunoglobulin, buffered aqueous glycerol solution,
物种
human

esiRNA

货号
说明
物种
EHU050101
MISSION® esiRNA, targeting human PARP1,
物种
human
EMU014921
MISSION® esiRNA, targeting mouse Parp1,
物种
mouse