Merck
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PDGFRB

platelet-derived growth factor receptor, beta polypeptide

别名:
CD140B, IBGC4, IMF1, JTK12, PDGFR, PDGFR-1, PDGFR1
物种:
UniProtKB ID:
基因ID:
  • Human(5159) Summary: This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the translocation, ETV6, leukemia gene, results in chronic myeloproliferative disorder with eosinophilia. [provided by RefSeq, Jul 2008]
  • Mouse(18596) platelet derived growth factor receptor, beta polypeptide
  • Rat(24629) platelet derived growth factor receptor, beta polypeptide
  • domestic guinea pig(100726506) platelet-derived growth factor receptor, beta polypeptide
  • naked mole-rat(101721151) platelet-derived growth factor receptor, beta polypeptide
  • Zebrafish(559529) platelet-derived growth factor receptor beta
  • chicken(770488) platelet-derived growth factor receptor, beta polypeptide
  • dog(442985) platelet-derived growth factor receptor, beta polypeptide
  • domestic cat(101084600) platelet-derived growth factor receptor, beta polypeptide
  • cow(527165) platelet-derived growth factor receptor, beta polypeptide
  • Domestic Rabbit(100342872) platelet-derived growth factor receptor, beta polypeptide
  • sheep(101122783) platelet-derived growth factor receptor, beta polypeptide

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ELISA

货号
说明
物种
小鼠PDGF-BB ELISA, for serum, plasma and cell culture supernatants,
物种
mouse
恒河猴PDGF R beta ELISA, for serum, plasma and cell culture supernatants,
物种
磷酸酪氨酸PDGFRB /血小板源性生长因子受体β ELISA试剂盒, ,
物种
human

Antibodies

货号
说明
物种反应性
应用
Anti-PDGFRB antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunofluorescence
western blot
Anti-PDGFR β antibody produced in rabbit, affinity isolated antibody,
物种反应性
human, mouse, rat
应用
ELISA
immunofluorescence

immunohistochemistry

western blot
Anti-PDGF Receptor β antibody produced in rabbit, affinity isolated antibody,
物种反应性
human, mouse, rat
应用
ELISA
immunofluorescence

immunohistochemistry

western blot
Monoclonal Anti-CD140b antibody produced in mouse, clone 18A2, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
flow cytometry
Monoclonal Anti-PDGFRB antibody produced in mouse, clone 4C12, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
ELISA
immunoprecipitation (IP)

proximity ligation assay

western blot

Small Molecule - Inhibitor

货号
说明
物种
2-苯基苯并咪唑, 97%,
物种
human
伊马替尼, ,
物种
human
SU 5416, ≥98% (HPLC),
物种
human, mouse
酪氨酸激酶抑制剂A9, solid,
物种
mouse, human
帕唑帕尼, ,
物种
human

Proteins

货号
说明
物种
PDGFRβ Protein, active, 50 µg, Active, recombinant human PDGF Receptor β, residues 557-end, containing an N-terminal His6-tag, for use in Kinase Assays.,
物种
human
PDGFRb/CD140b human, recombinant, expressed in HEK 293 cells, ≥95% (SDS-PAGE),
物种
human
PDGFRb active human, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE),
物种
human
PDGFRβ(557-end), active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
物种
human

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting human PDGFRB,
物种
human