CN
PLAU
plasminogen activator, urokinase
别名:
ATF, BDPLT5, QPD, UPA, URK, u-PA
物种:
Human PLAU (5328), Mouse Plau (18792), Rat Plau (25619), cow PLAU (281408), dog PLAU (403426), domestic guinea pig Plau (100726129), Domestic Rabbit PLAU (100008633), chicken PLAU (396424), domestic cat PLAU (101098338), naked mole-rat Plau (101717852)
UniProtKB ID:
基因ID:
- Human(5328) Summary: This gene encodes a serine protease involved in degradation of the extracellular matrix and possibly tumor cell migration and proliferation. A specific polymorphism in this gene may be associated with late-onset Alzheimer's disease and also with decreased affinity for fibrin-binding. This protein converts plasminogen to plasmin by specific cleavage of an Arg-Val bond in plasminogen. Plasmin in turn cleaves this protein at a Lys-Ile bond to form a two-chain derivative in which a single disulfide bond connects the amino-terminal A-chain to the catalytically active, carboxy-terminal B-chain. This two-chain derivative is also called HMW-uPA (high molecular weight uPA). HMW-uPA can be further processed into LMW-uPA (low molecular weight uPA) by cleavage of chain A into a short chain A (A1) and an amino-terminal fragment. LMW-uPA is proteolytically active but does not bind to the uPA receptor. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2009]
- Mouse(18792) plasminogen activator, urokinase
- Rat(25619) plasminogen activator, urokinase
- cow(281408) plasminogen activator, urokinase
- dog(403426) plasminogen activator, urokinase
- domestic guinea pig(100726129) plasminogen activator, urokinase
- Domestic Rabbit(100008633) plasminogen activator, urokinase
- chicken(396424) plasminogen activator, urokinase
- domestic cat(101098338) plasminogen activator, urokinase
- naked mole-rat(101717852) plasminogen activator, urokinase
- sheep(100302501) plasminogen activator, urokinase
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Antibodies
货号
说明
物种反应性
应用
Anti-PLAU antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunofluorescence
immunohistochemistry
immunohistochemistry
Anti-Plasminogen Activator/PLAU antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
物种反应性
human
应用
ELISA
western blot
western blot
Anti-Urokinase Antibody, NT fragment, clone 10D.7.2, clone 10D.7.2, Chemicon®, from mouse,
物种反应性
human
应用
ELISA
western blot
western blot
Anti-PLAU antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunohistochemistry
Anti-Urokinase Antibody, NT fragment, clone 2G6.2, clone 2G6.2, Chemicon®, from mouse,
物种反应性
human
应用
ELISA
western blot
western blot
Kits
货号
说明
物种
uPA活性检测试剂盒, The uPA Activity Assay Kit provides a quick, efficient & sensitive system for evaluation of uPA activity & for screening of uPA inhibitors.,
物种
human
PAI Activity Assay, The PAI Activity Assay Kit provides a quick, efficient & sensitive system for evaluation of inhibition of uPA activity by PAI & for screening of uPA inhibitors.,
物种
human
Proteins
货号
说明
物种
esiRNA
货号
说明
物种