Merck
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POLD2

polymerase (DNA directed), delta 2, accessory subunit

别名:
物种:
UniProtKB ID:
基因ID:
  • Human(5425) Summary: This gene encodes the 50-kDa catalytic subunit of DNA polymerase delta. DNA polymerase delta possesses both polymerase and 3' to 5' exonuclease activity and plays a critical role in DNA replication and repair. The encoded protein is required for the stimulation of DNA polymerase delta activity by the processivity cofactor proliferating cell nuclear antigen (PCNA). Expression of this gene may be a marker for ovarian carcinomas. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 5. [provided by RefSeq, Mar 2012]
  • Mouse(18972) polymerase (DNA directed), delta 2, regulatory subunit
  • Rat(289758) polymerase (DNA directed), delta 2, accessory subunit
  • domestic cat(101095089) polymerase (DNA directed), delta 2, accessory subunit
  • dog(482686) polymerase (DNA directed), delta 2, accessory subunit
  • cow(281991) polymerase (DNA directed), delta 2, regulatory subunit 50kDa
  • sheep(101117838) polymerase (DNA directed), delta 2, accessory subunit
  • Domestic Rabbit(100358263) polymerase (DNA directed), delta 2, accessory subunit
  • domestic guinea pig(100727561) polymerase (DNA directed), delta 2, accessory subunit
  • naked mole-rat(101722261) polymerase (DNA directed), delta 2, accessory subunit
  • chicken(100859398) polymerase (DNA directed), delta 2, accessory subunit
  • Thale Cress(818812) DNA polymerase delta subunit 2
  • Zebrafish(796456) polymerase (DNA directed), delta 2, regulatory subunit

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Antibodies

货号
说明
物种反应性
应用
Anti-POLD2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human, mouse, rat
应用
immunofluorescence
immunohistochemistry

western blot
Anti-POLD2 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
western blot
Anti-DNA polymerase δ p50 antibody, Rat monoclonal, clone PDK 7B4, purified from hybridoma cell culture,
物种反应性
human
应用
immunocytochemistry
immunoprecipitation (IP)

western blot

Small Molecule - Inhibitor

货号
说明
物种
胞嘧啶 β-D-呋喃阿拉伯糖苷, Vetec, reagent grade, 90%,
物种
human
胞嘧啶β-D-呋喃阿拉伯糖苷 盐酸盐, crystalline,
物种
human
阿糖胞苷, Pharmaceutical Secondary Standard; Certified Reference Material,
物种
human
阿糖胞苷, European Pharmacopoeia (EP) Reference Standard,
物种
human
阿糖胞嘧啶, United States Pharmacopeia (USP) Reference Standard,
物种
human

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting mouse Pold2,
物种
mouse
MISSION® esiRNA, targeting human POLD2,
物种
human