CN
PRKACA
protein kinase, cAMP-dependent, catalytic, alpha
别名:
PKACA
物种:
Human PRKACA (5566), Mouse Prkaca (18747), Rat Prkaca (25636), naked mole-rat Prkaca (101707235), sheep PRKACA (443094), domestic guinea pig Prkaca (100735694), dog PRKACA (403556), Horse PRKACA (100064302), cow PRKACA (282322), domestic cat PRKACA (101090494)
UniProtKB ID:
基因ID:
- Human(5566) Summary: cAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP-dependent protein kinase, which transduces the signal through phosphorylation of different target proteins. The inactive kinase holoenzyme is a tetramer composed of two regulatory and two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits have been identified in humans. The protein encoded by this gene is a member of the Ser/Thr protein kinase family and is a catalytic subunit of cAMP-dependent protein kinase. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008]
- Mouse(18747) protein kinase, cAMP dependent, catalytic, alpha
- Rat(25636) protein kinase, cAMP-dependent, catalytic, alpha
- naked mole-rat(101707235) protein kinase, cAMP-dependent, catalytic, alpha
- sheep(443094) protein kinase, cAMP-dependent, catalytic, alpha
- domestic guinea pig(100735694) protein kinase, cAMP-dependent, catalytic, alpha
- dog(403556) protein kinase, cAMP-dependent, catalytic, alpha
- Horse(100064302) protein kinase, cAMP-dependent, catalytic, alpha
- cow(282322) protein kinase, cAMP-dependent, catalytic, alpha
- domestic cat(101090494) protein kinase, cAMP-dependent, catalytic, alpha
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Antibodies
货号
说明
物种反应性
应用
Anti-PKA α antibody produced in rabbit, affinity isolated antibody,
物种反应性
human, mouse, rat
应用
ELISA
immunofluorescence
immunohistochemistry
western blot
immunofluorescence
immunohistochemistry
western blot
Anti-phospho-PKA α/β CAT (pThr197) antibody produced in rabbit, affinity isolated antibody,
物种反应性
human, mouse
应用
immunohistochemistry
western blot
western blot
Anti-PRKACA antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
物种反应性
human
应用
immunofluorescence
western blot
western blot
Anti-PKA C-α Antibody, clone 2E17 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
物种反应性
human, mouse, rat
应用
affinity binding assay
immunocytochemistry
immunohistochemistry
western blot
immunocytochemistry
immunohistochemistry
western blot
ANTI-PKA C-ALPHA/PKA C-BETA(N-TERMINAL) antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
物种反应性
human, mouse
应用
immunohistochemistry
western blot
western blot
Small Molecule - Inhibitor
货号
说明
物种
Protein Kinase A inhibitor fragment 14-22, myristoylated trifluoroacetate salt, ≥90% (HPLC), lyophilized powder,
物种
mouse, rat, human