Merck
CN

PRNP

prion protein

别名:
ASCR, AltPrP, CD230, CJD, GSS, KURU, PRIP, PrP, PrP27-30, PrP33-35C, PrPc, p27-30
物种:
UniProtKB ID:
基因ID:
  • Human(5621) Summary: The protein encoded by this gene is a membrane glycosylphosphatidylinositol-anchored glycoprotein that tends to aggregate into rod-like structures. The encoded protein contains a highly unstable region of five tandem octapeptide repeats. This gene is found on chromosome 20, approximately 20 kbp upstream of a gene which encodes a biochemically and structurally similar protein to the one encoded by this gene. Mutations in the repeat region as well as elsewhere in this gene have been associated with Creutzfeldt-Jakob disease, fatal familial insomnia, Gerstmann-Straussler disease, Huntington disease-like 1, and kuru. An overlapping open reading frame has been found for this gene that encodes a smaller, structurally unrelated protein, AltPrp. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2012]
  • Mouse(19122) prion protein
  • Rat(24686) prion protein
  • domestic cat(493886) prion protein
  • chicken(396452) prion protein
  • Horse(100065904) prion protein
  • naked mole-rat(101710391) prion protein
  • cow(281427) prion protein
  • domestic guinea pig(100714701) prion protein
  • sheep(493887) prion protein
  • Domestic Rabbit(100345744) prion protein
  • dog(485783) prion protein

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Small Molecule - Antagonist

货号
说明
物种
吩嗪, 98%,
物种
human
卡马西平, meets USP testing specifications,
物种
rat, human
氟哌啶醇, powder,
物种
human, rat

Antibodies

货号
说明
物种反应性
应用
抗朊病毒蛋白抗体,a.a.109-112,克隆3F4, clone 3F4, Chemicon®, from mouse,
物种反应性
hamster, human
应用
ELISA
immunohistochemistry

immunoprecipitation (IP)

western blot
Anti-Prion Protein Antibody, clone 3D0J9, Rabbit Monoclonal, ,
物种反应性
human, rat
应用
western blot
Anti-Prion Protein Antibody, clone POM1, clone POM1, from mouse,
物种反应性
human, mouse
应用
immunofluorescence
immunohistochemistry

immunoprecipitation (IP)

western blot
Anti-PRNP antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunohistochemistry
Anti-PrP, clone DRM2-118 Antibody, clone DRM2-118, from mouse,
物种反应性
bovine, hamster, human, mouse, porcine, rat, sheep
应用
ELISA
immunohistochemistry

western blot

Proteins

货号
说明
物种
Prion Protein, recombinant, ,
物种
cow
Prion Protein Fragment 106-126 Human, ≥90% (HPLC), solid,
物种
human
Prion Protein Fragment 106-126 Scrambled Human, ≥85% (HPLC), solid,
物种
human

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting human PRNP,
物种
human