CN
PRKCA
protein kinase C, alpha
别名:
AAG6, PKC-alpha, PKCA, PRKACA
物种:
Human PRKCA (5578), Mouse Prkca (18750), Rat Prkca (24680), Horse PRKCA (100063318), dog PRKCA (490904), Domestic Rabbit PRKCA (100037720), domestic cat PRKCA (101086433), sheep PRKCA (101110074), Zebrafish prkca (497384), chicken PRKCA (417430) ...展开
UniProtKB ID:
基因ID:
- Human(5578) Summary: Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This kinase has been reported to play roles in many different cellular processes, such as cell adhesion, cell transformation, cell cycle checkpoint, and cell volume control. Knockout studies in mice suggest that this kinase may be a fundamental regulator of cardiac contractility and Ca(2+) handling in myocytes. [provided by RefSeq, Jul 2008]
- Mouse(18750) protein kinase C, alpha
- Rat(24680) protein kinase C, alpha
- Horse(100063318) protein kinase C, alpha
- dog(490904) protein kinase C, alpha
- Domestic Rabbit(100037720) protein kinase C, alpha
- domestic cat(101086433) protein kinase C, alpha
- sheep(101110074) protein kinase C, alpha
- Zebrafish(497384) protein kinase C, alpha
- chicken(417430) protein kinase C, alpha
- cow(282001) protein kinase C, alpha
- domestic guinea pig(100302324) protein kinase C, alpha
- domestic guinea pig(100713627) protein kinase C, alpha
- naked mole-rat(101716044) protein kinase C, alpha
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Small Molecule - Activator
货号
说明
物种
Small Molecule - Agonist
货号
说明
物种
Antibodies
货号
说明
物种反应性
应用
Anti-Protein kinase C antibody, Mouse monoclonal, clone MC5, purified from hybridoma cell culture,
物种反应性
bovine, chicken, fish, human, mouse, rabbit, rat
应用
immunocytochemistry
immunofluorescence
immunoprecipitation (IP)
western blot
immunofluorescence
immunoprecipitation (IP)
western blot
Anti-phospho-PKCα (Ser657/Tyr658) Antibody, Upstate®, from rabbit,
物种反应性
human, rabbit, rat
应用
ELISA
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Anti-PKC-PAN antibody produced in rabbit, affinity isolated antibody,
物种反应性
human, mouse, rat
应用
ELISA
immunofluorescence
immunohistochemistry
western blot
immunofluorescence
immunohistochemistry
western blot
Anti-Phospho-PKC (pan) (βII Ser660) antibody produced in rabbit, ,
物种反应性
human, mouse, rat
应用
western blot
Anti-phospho-PKC α (pTyr657) antibody produced in rabbit, affinity isolated antibody,
物种反应性
human
应用
western blot
Small Molecule - Inhibitor
货号
说明
物种
PKC/CaMK Inhibitor Cocktail, The PKC/CaMK Inhibitor Cocktail controls the biological activity of PKC/CaMK. This small molecule/inhibitor is primarily used for Biochemicals applications.,
物种
human
Proteins
货号
说明
物种
PKCα Protein, active, 10 µg, Active, recombinant, full-length human PKCα, containing N-terminal His6 tag. For use in Kinase Assays.,
物种
human
PKC-α，活性，GST 标记 from Xanopus sp., PRECISIO®, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
物种
Protein kinase Cα isozyme human, ≥70% (SDS-PAGE), recombinant, expressed in baculovirus infected insect cells, buffered aqueous glycerol solution,
物种
human