Merck
CN

SLC6A4

solute carrier family 6 (neurotransmitter transporter), member 4

别名:
5-HTT, 5-HTTLPR, 5HTT, HTT, OCD1, SERT, SERT1, hSERT
物种:
UniProtKB ID:
基因ID:
  • Human(6532) Summary: This gene encodes an integral membrane protein that transports the neurotransmitter serotonin from synaptic spaces into presynaptic neurons. The encoded protein terminates the action of serotonin and recycles it in a sodium-dependent manner. This protein is a target of psychomotor stimulants, such as amphetamines and cocaine, and is a member of the sodium:neurotransmitter symporter family. A repeat length polymorphism in the promoter of this gene has been shown to affect the rate of serotonin uptake and may play a role in sudden infant death syndrome, aggressive behavior in Alzheimer disease patients, and depression-susceptibility in people experiencing emotional trauma. [provided by RefSeq, Jul 2008]
  • Mouse(15567) solute carrier family 6 (neurotransmitter transporter, serotonin), member 4
  • Rat(25553) solute carrier family 6 (neurotransmitter transporter), member 4
  • domestic guinea pig(100135619) solute carrier family 6 (neurotransmitter transporter, serotonin), member 4
  • naked mole-rat(101705584) solute carrier family 6 (neurotransmitter transporter, serotonin), member 4
  • Domestic Rabbit(100340600) solute carrier family 6 (neurotransmitter transporter, serotonin), member 4
  • Domestic Rabbit(100351801) solute carrier family 6 (neurotransmitter transporter, serotonin), member 4
  • dog(491184) solute carrier family 6 (neurotransmitter transporter, serotonin), member 4
  • domestic cat(101091163) solute carrier family 6 (neurotransmitter transporter, serotonin), member 4
  • Horse(100053721) solute carrier family 6 (neurotransmitter transporter, serotonin), member 4
  • cow(282365) solute carrier family 6 (neurotransmitter transporter, serotonin), member 4
  • chicken(404747) solute carrier family 6 (neurotransmitter transporter, serotonin), member 4

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Small Molecule - Antagonist

货号
说明
物种
N -乙基马来酰亚胺, BioUltra, ≥99.0% (HPLC),
物种
human
N -乙基马来酰亚胺, purum p.a., ≥99.0% (HPLC),
物种
human
N -乙基马来酰亚胺, BioXtra, ≥98% (HPLC),
物种
human
4-苄基吡啶, 98%,
物种
rat
二苯基-4-吡啶基甲烷, 99%,
物种
rat

Antibodies

货号
说明
物种反应性
应用
Anti-Serotonin transporter Antibody, clone 5T7M2, Rabbit Monoclonal, ,
物种反应性
human, rat
应用
immunofluorescence
western blot
Anti-SLC6A4/5HTT/SERT antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
物种反应性
human
应用
ELISA
western blot
Anti-Serotonin Transporter (N-terminal) antibody produced in rabbit, ~1.5 mg/mL, affinity isolated antibody, buffered aqueous solution,
物种反应性
human
应用
western blot
Anti-Serotonin (5-HT) Transporter (602-622) Rabbit pAb, lyophilized, Calbiochem®,
物种反应性
mouse, rat
应用
Anti-SLC6A4 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
物种反应性
human, mouse
应用
western blot

Small Molecule - Inhibitor

货号
说明
物种
氟西汀盐酸盐, Pharmaceutical Secondary Standard; Certified Reference Material,
物种
human
帕罗西汀, Pharmaceutical Secondary Standard; Certified Reference Material,
物种
human
氢溴酸西酞普兰, Pharmaceutical Secondary Standard; Certified Reference Material,
物种
human
氟西汀 盐酸盐 溶液, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®,
物种
human
氯米帕明, Pharmaceutical Secondary Standard; Certified Reference Material,
物种
human

Proteins

货号
说明
物种
PrEST Antigen SLC6A4, Prestige Antigens Powered by Atlas Antibodies, buffered aqueous solution,
物种
human

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting human SLC6A4,
物种
human