Merck
CN

THRB

thyroid hormone receptor, beta

别名:
C-ERBA-2, C-ERBA-BETA, ERBA2, GRTH, NR1A2, PRTH, THR1, THRB1, THRB2
物种:
Human THRB (7068), Mouse Thrb (21834), Rat Thrb (24831), Domestic Rabbit THRB (100303763), chicken THRB (396431), cow THRB (788329), domestic cat THRB (101084821), Horse THRB (100051615), dog THRB (403599), naked mole-rat Thrb (101719651) ...展开
UniProtKB ID:
P10828, B3KU79, P37243, Q13986, Q3KP35, Q6WGL2, Q9UD41
基因ID:
  • Human(7068) Summary: The protein encoded by this gene is a nuclear hormone receptor for triiodothyronine. It is one of the several receptors for thyroid hormone, and has been shown to mediate the biological activities of thyroid hormone. Knockout studies in mice suggest that the different receptors, while having certain extent of redundancy, may mediate different functions of thyroid hormone. Mutations in this gene are known to be a cause of generalized thyroid hormone resistance (GTHR), a syndrome characterized by goiter and high levels of circulating thyroid hormone (T3-T4), with normal or slightly elevated thyroid stimulating hormone (TSH). Several alternatively spliced transcript variants encoding the same protein have been observed for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(21834) thyroid hormone receptor beta
  • Rat(24831) thyroid hormone receptor beta
  • Domestic Rabbit(100303763) thyroid hormone receptor, beta
  • chicken(396431) thyroid hormone receptor, beta
  • cow(788329) thyroid hormone receptor, beta
  • domestic cat(101084821) thyroid hormone receptor, beta
  • Horse(100051615) thyroid hormone receptor, beta
  • dog(403599) thyroid hormone receptor, beta
  • naked mole-rat(101719651) thyroid hormone receptor, beta
  • domestic guinea pig(100721125) thyroid hormone receptor, beta
  • Zebrafish(30607) thyroid hormone receptor beta

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Small Molecule - Agonist

货号
说明
物种
T-073
L-甲状腺素（T4） 溶液, 100 μg/mL in methanol with 0.1N NH3, ampule of 1 mL, certified reference material, Cerilliant®,
物种
human
T-074
3,3′,5-三碘-L-甲状腺原氨酸（T3） 溶液, 100 μg/mL in methanol with 0.1N NH3, ampule of 1 mL, certified reference material, Cerilliant®,
物种
human

Small Molecule - Antagonist

货号
说明
物种
T2877
3,3′,5-三碘代-L-甲状腺原氨酸, ≥95% (HPLC), powder,
物种
rat, human
T7650
替拉曲可, ≥90%,
物种
rat, human

Antibodies

货号
说明
物种反应性
应用
ABN25
Anti-Thyroid Hormone Receptor β-1 Antibody, from rabbit, purified by affinity chromatography,
物种反应性
human, mouse, rat
应用
western blot
SAB4502969
Anti-Thyroid Hormone Receptor β, N-Terminal antibody produced in rabbit, affinity isolated antibody,
物种反应性
human, mouse, rat
应用
ELISA
immunohistochemistry
western blot
HPA061035
Anti-THRB antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
物种反应性
human
应用
immunofluorescence
SAB2501038
Anti-THRB antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
物种反应性
canine, human, mouse, rat
应用
ELISA
western blot
SAB4504736
Anti-phospho-TR-β1 (pSer142) antibody produced in rabbit, affinity isolated antibody,
物种反应性
human, mouse, rat
应用
ELISA
western blot

Small Molecule - Blocker

货号
说明
物种
T2877
3,3′,5-三碘代-L-甲状腺原氨酸, ≥95% (HPLC), powder,
物种
rat, human

Proteins

货号
说明
物种
SRP2020
TR, β 1 isoform human, recombinant, expressed in E. coli, ≥70% (SDS-PAGE),
物种
human

esiRNA

货号
说明
物种
EHU083461
MISSION® esiRNA, targeting human THRB,
物种
human