Merck
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VEGFA

vascular endothelial growth factor A

Synonyms:
MVCD1, VEGF, VPF
Species:
UniProtKB ID:
Gene ID:
  • Human(7422) Summary: This gene is a member of the PDGF/VEGF growth factor family and encodes a protein that is often found as a disulfide linked homodimer. This protein is a glycosylated mitogen that specifically acts on endothelial cells and has various effects, including mediating increased vascular permeability, inducing angiogenesis, vasculogenesis and endothelial cell growth, promoting cell migration, and inhibiting apoptosis. Elevated levels of this protein is linked to POEMS syndrome, also known as Crow-Fukase syndrome. Mutations in this gene have been associated with proliferative and nonproliferative diabetic retinopathy. Alternatively spliced transcript variants, encoding either freely secreted or cell-associated isoforms, have been characterized. There is also evidence for the use of non-AUG (CUG) translation initiation sites upstream of, and in-frame with the first AUG, leading to additional isoforms. [provided by RefSeq, Jul 2008]
  • Mouse(22339) vascular endothelial growth factor A
  • Rat(83785) vascular endothelial growth factor A
  • domestic cat(493845) vascular endothelial growth factor A
  • cow(281572) vascular endothelial growth factor A
  • sheep(443103) vascular endothelial growth factor A
  • Goat(100860957) vascular endothelial growth factor A
  • Domestic Rabbit(100008899) vascular endothelial growth factor A
  • domestic guinea pig(100713483) vascular endothelial growth factor A
  • domestic guinea pig(100462897) vascular endothelial growth factor A
  • naked mole-rat(101702403) vascular endothelial growth factor A
  • chicken(395909) vascular endothelial growth factor A
  • dog(403802) vascular endothelial growth factor A
  • Horse(100033839) vascular endothelial growth factor A

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ELISA

Product Number
Description
Species
Mouse VEGF ELISA Kit, for serum, plasma, cell culture supernatant,
Species
mouse
Ovine VEGF-A ELISA, for serum, plasma and cell culture supernatants,
Species
sheep
Canine VEGFA / Vascular Endothelial Growth Factor A ELISA Kit, ,
Species
dog
Porcine VEGF-A ELISA Kit, for cell culture supernatants, plasma, and serum samples,
Species
Bovine VEGF-A ELISA, for serum, plasma and cell culture supernatants,
Species
cow

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-VEGF Antibody, clone JH, clone JH, Upstate®, from mouse,
Species Reactivity
human, mouse, rabbit, rat
Application
immunohistochemistry
Anti-VEGF Antibody, Alexa Fluor 488 Conjugate, from rabbit, ALEXA FLUOR 488,
Species Reactivity
human, nonhuman primates, rat
Application
immunocytochemistry
Anti-VEGF 165b Antibody, clone 56/1, clone 56/1, 1 mg/mL, from mouse,
Species Reactivity
human, mouse, rat
Application
ELISA
immunohistochemistry

western blot
Anti-VEGF Antibody, from rabbit, purified by affinity chromatography,
Species Reactivity
human, mouse, primate, rat
Application
immunohistochemistry
western blot
Anti-VEGF Receptor-3 Antibody, extracellular domain, clone 9D9F9, ascites fluid, clone 9D9F9, Chemicon®,
Species Reactivity
human
Application
flow cytometry
immunofluorescence

immunohistochemistry

immunoprecipitation (IP)

western blot

Small Molecule - Inhibitor

Product Number
Description
Species
Tranilast, ≥98% (HPLC), powder,
Species
human

Proteins

Product Number
Description
Species
VEGF164 from mouse, recombinant, expressed in HEK 293 cells, ≥95% (SDS-PAGE),
Species
mouse
VEGF Protein, Human recombinant, The human recombinant VEGF Protein is available in a 10 µg format.,
Species
human
VEGF165 from rat, recombinant, expressed in E. coli, ≥98% (SDS-PAGE),
Species
rat

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human VEGFA,
Species
human
MISSION® esiRNA, targeting mouse Vegfa,
Species
mouse